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  • Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function
    [作者:Yona, S; Lin, HH; Dri, P; Davies, JQ; Hayhoe, RPG; Lewis, SM; Heinsbroek, SEM; Brown, KA; Perretti, M; Hamann, J; Treacher, DF; Gordon, S; Stacey, M,期刊:FASEB Journal, 页码:741-751 , 文章类型: Article,,卷期:2008年22-3]
  • At present, similar to 150 different members of the adhesion-G protein-coupled receptor (GPCR) family have been identified in metazoans. Surprisingly, very little is known about their function, although they all possess ...
  • Dose translation from animal to human studies revisited
    [作者:Reagan-Shaw, S; Nihal, M; Ahmad, N,期刊:FASEB Journal, 页码:659-661 , 文章类型: Article,,卷期:2008年22-3]
  • As new drugs are developed, it is essential to appropriately translate the drug dosage from one animal species to another. A misunderstanding appears to exist regarding the appropriate method for allometric dose translat...