- Impaired skeletal muscle development and function in male, but not female, genomic androgen receptor knockout mice
[作者：MacLean, HE; Chiu, WSM; Notini, AJ; Axell, AM; Davey, RA; McManus, JF; Ma, C; Plant, DR; Lynch, GS; Zajac, JD,期刊：FASEB Journal, 页码：2676-2689 , 文章类型： Article，,卷期：2008年22-8]
- To identify mechanisms of anabolic androgen action in muscle, we generated male and female genomic androgen receptor (AR) knockout (ARKO) mice, and characterized muscle mass, contractile function, and gene expression. Mu...
- The Wilms' tumor suppressor Wt1 activates transcription of the erythropoietin receptor in hematopoietic progenitor cells
[作者：Kirschner, KM; Hagen, P; Hussels, CS; Ballmaier, M; Scholz, H; Dame, C,期刊：FASEB Journal, 页码：2690-2701 , 文章类型： Article，,卷期：2008年22-8]
- The Wilms' tumor protein Wt1 is required for embryonic development and has been implicated in hematologic disorders. Since Wt1 deficiency may compromise the proliferation and differentiation of erythroid progenitor cells...
- IFN-gamma enhances neurogenesis in wild-type mice and in a mouse model of Alzheimer's disease
[作者：Baron, R; Nemirovsky, A; Harpaz, I; Cohen, H; Owens, T; Monsonego, A,期刊：FASEB Journal, 页码：2843-2852 , 文章类型： Article，,卷期：2008年22-8]
- The generation of new neurons and glia from a precursor stem cell appears to take place in the adult brain. However, new neurons generated in the dentate gyrus decline sharply with age and to an even greater extent in ne...
- Exercise-induced protection against myocardial apoptosis and necrosis: MnSOD, calcium-handling proteins, and calpain
[作者：French, JP; Hamilton, KL; Quindry, JC; Lee, Y; Upchurch, PA; Powers, SK,期刊：FASEB Journal, 页码：2862-2871 , 文章类型： Article，,卷期：2008年22-8]
- Exercise provides protection against myocardial ischemia-reperfusion (IR) injury. Understanding the mechanisms of this protection may lead to new interventions for the prevention and/or treatment of heart disease. Althou...
- AP-2 alpha and AP-2 gamma regulate tumor progression via specific genetic programs
[作者：Orso, F; Penna, E; Cimino, D; Astanina, E; Maione, F; Valdembri, D; Giraudo, E; Serini, G; Sismondi, P; De Bortoli, M; Taverna, D,期刊：FASEB Journal, 页码：2702-2714 , 文章类型： Article，,卷期：2008年22-8]
- The events occurring during tumor formation and progression display similarities to some of the steps in embryonic morphogenesis. The family of AP-2 proteins consists of five different transcription factors ( alpha,beta,...
- M protein-mediated plasminogen binding is essential for the virulence of an invasive Streptococcus pyogenes isolate
[作者：Sanderson-Smith, ML; Dinkla, K; Cole, JN; Cork, AJ; Maamary, PG; McArthur, JD; Chhatwal, GS; Walker, MJ,期刊：FASEB Journal, 页码：2715-2722 , 文章类型： Article，,卷期：2008年22-8]
- The human protease plasmin plays a crucial role in the capacity of the group A streptococcus (GAS; Streptococus pyogenes) to initiate invasive disease. The GAS strain NS88.2 was isolated from a case of bacteremia from th...
- A protein complex in the brush-border membrane explains a Hartnup disorder allele
[作者：Kowalczuk, S; Broer, A; Tietze, N; Vanslambrouck, JM; Rasko, JEJ; Broer, S,期刊：FASEB Journal, 页码：2880-2887 , 文章类型： Article，,卷期：2008年22-8]
- Protein absorption in the intestine is mediated by proteases and brush-border peptidases together with peptide and amino acid transporters. Neutral amino acids are generated by a variety of aminopeptidases and carboxypep...
- Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier
[作者：Hartz, AMS; Bauer, B; Block, ML; Hong, JS; Miller, DS,期刊：FASEB Journal, 页码：2723-2733 , 文章类型： Article，,卷期：2008年22-8]
- Here, we report that diesel exhaust particles (DEPs), a major constituent of urban air pollution, affect blood-brain barrier function at the tissue, cellular, and molecular levels. Isolated rat brain capillaries exposed ...
- Association of glycosylphosphatidylinositol-anchored protein with retroviral particles
[作者：Metzner, C; Mostegl, MM; Gunzburg, WH; Salmons, B; Dangerfield, JA,期刊：FASEB Journal, 页码：2734-2739 , 文章类型： Article，,卷期：2008年22-8]
- We describe for the first time the association of glycosylphosphatidylinositol (GPI)-anchored proteins with retroviral and lentiviral particles, similar to a process well established for cells, termed "painting." The aim...
- Calcium-permeable AMPA receptors containing Q/R-unedited GluR2 direct human neural progenitor cell differentiation to neurons
[作者：Whitney, NP; Peng, H; Erdmann, NB; Tian, C; Monaghan, DT; Zheng, JC,期刊：FASEB Journal, 页码：2888-2900 , 文章类型： Article，,卷期：2008年22-8]
- We identify calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors on human neural progenitor cells (NPCs) and present a physiological role in neurogenesis. RNA editing of the GluR2 s...
- Protein ubiquitination is modulated by O-GlcNAc glycosylation
[作者：Guinez, C; Mir, AM; Dehennaut, V; Cacan, R; Harduin-Lepers, A; Michalski, JC; Lefebvre, T,期刊：FASEB Journal, 页码：2901-2911 , 文章类型： Article，,卷期：2008年22-8]
- During the past two decades, O-GlcNAc modification of cytosolic and nuclear proteins has been intensively studied. Nevertheless, the function of this post-translational modification remains unclear. It has been recently ...
- Evidence for defective mesolimbic dopamine exocytosis in obesity-prone rats
[作者：Geiger, BM; Behr, GG; Frank, LE; Caldera-Siu, AD; Beinfeld, MC; Kokkotou, EG; Pothos, EN,期刊：FASEB Journal, 页码：2740-2746 , 文章类型： Article，,卷期：2008年22-8]
- The association between dietary obesity and mesolimbic systems that regulate hedonic aspects of feeding is currently unresolved. In the present study, we examined differences in baseline and stimulated central dopamine l...
- Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells
[作者：Spadaro, M; Caorsi, C; Ceruti, P; Varadhachary, A; Forni, G; Pericle, F; Giovarelli, M,期刊：FASEB Journal, 页码：2747-2757 , 文章类型： Article，,卷期：2008年22-8]
- Lactoferrin (LF) is an important protein component of the innate immune system that is broadly distributed within the body fluids. LF is endowed with multiple biological activities. Talactoferrin (TLF), a recombinant hum...
- Sarcoplasmic reticulum calcium uptake and speed of relaxation are depressed in nebulin-free skeletal muscle
[作者：Ottenheijm, CAC; Fong, C; Vangheluwe, P; Wuytack, F; Babu, GJ; Periasamy, M; Witt, CC; Labeit, S; Granzier, H,期刊：FASEB Journal, 页码：2912-2919 , 文章类型： Article，,卷期：2008年22-8]
- Previous work suggested that altered Ca2+ homeostasis might contribute to dysfunction of nebulin-free muscle, as gene expression analysis revealed that the sarco(endo) plasmic reticulum Ca2+-ATPase (SERCA)-inhibitor sarc...
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