- Detection of migration of locally implanted AC133(+) stem cells by cellular magnetic resonance imaging with histological findings
[作者:Arbab, AS; Janic, B; Knight, RA; Anderson, SA; Pawelczyk, E; Rad, AM; Read, EJ; Pandit, SD; Frank, JA,期刊:FASEB Journal, 页码:3234-3246 , 文章类型: Article,,卷期:2008年22-9]
- This study investigated the factors responsible for migration and homing of magnetically labeled AC133(+) cells at the sites of active angiogenesis in tumor. AC133(+) cells labeled with ferumoxide-protamine sulfate were ...
- Chaperone displacement from mutant cystic fibrosis transmembrane conductance regulator restores its function in human airway epithelia
[作者:Sun, F; Mi, ZB; Condliffe, SB; Bertrand, CA; Gong, XY; Lu, XL; Zhang, RL; Latoche, JD; Pilewski, JM; Robbins, PD; Frizzell, RA,期刊:FASEB Journal, 页码:3255-3263 , 文章类型: Article,,卷期:2008年22-9]
- Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause cystic fibrosis (CF). The most common mutation, Delta F508, omits the phenylalanine residue at position 508 in the first nucleotide b...
- VEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinase
[作者:Wright, GL; Maroulakou, IG; Eldridge, J; Liby, TL; Sridharan, V; Tsichlis, PN; Muise-Helmericks, RC,期刊:FASEB Journal, 页码:3264-3275 , 文章类型: Article,,卷期:2008年22-9]
- The growth factor, vascular endothelial growth factor (VEGF), induces angiogenesis and promotes endothelial cell (EC) proliferation. Affymetrix gene array analyses show that VEGF stimulates the expression of a cluster of...
- Differential expression of 5 '-UTR splice variants of the adenosine A(2A) receptor gene in human granulocytes: identification, characterization, and functional impact on activation
[作者:Kreth, S; Ledderose, C; Kaufmann, I; Groeger, G; Thiel, M,期刊:FASEB Journal, 页码:3276-3286 , 文章类型: Article,,卷期:2008年22-9]
- A key step in the pathogenesis of sepsis is the excessive and uncontrolled activation of polymorphonuclear neutrophils (PMNs). An inflammation-controlling function of adenosine receptors has been presumed; however, their...
- Suppressor of cytokine signaling 1 inhibits IFN-gamma inflammatory signaling in human keratinocytes by sustaining ERK1/2 activation
[作者:Madonna, S; Scarponi, C; De Pita, O; Albanesi, C,期刊:FASEB Journal, 页码:3287-3297 , 文章类型: Article,,卷期:2008年22-9]
- IFN-gamma is a pleiotropic cytokine importantly involved in the development of skin inflammatory responses. Epidermal keratinocytes are extremely susceptible to IFN-gamma action, but, once transduced with the suppressors...
- Identification of molecular determinants of channel gating in the transient receptor potential box of vanilloid receptor I
[作者:Valente, P; Garcia-Sanz, N; Gomis, A; Fernandez-Carvajal, A; Fernandez-Ballester, G; Viana, F; Belmonte, C; Ferrer-Montiel, A,期刊:FASEB Journal, 页码:3298-3309 , 文章类型: Article,,卷期:2008年22-9]
- Transient receptor potential vanilloid receptor subtype I (TRPV1) is an ion channel gated by physical and chemical stimuli that belongs to the TRPV protein family. TRPV receptors contain a highly conserved, 6-mer segment...
- A peptide inhibitor of the urokinase/urokinase receptor system inhibits alteration of the blood-retinal barrier in diabetes
[作者:Navaratna, D; Menicucci, G; Maestas, J; Srinivasan, R; McGuire, P; Das, A,期刊:FASEB Journal, 页码:3310-3317 , 文章类型: Article,,卷期:2008年22-9]
- One of the major complications of diabetes is the alteration of the blood-retinal barrier, leading to retinal edema and consequent vision loss. The aim of this study was to evaluate the role of the urokinase plasminogen ...
- Nongenomic actions of estradiol compared with estrone and estriol in pituitary tumor cell signaling and proliferation
[作者:Watson, CS; Jeng, YJ; Kochukov, MY,期刊:FASEB Journal, 页码:3328-3336 , 文章类型: Article,,卷期:2008年22-9]
- Physiological estrogens, including estrone (E-1), estradiol (E-2), and estriol (E-3), fluctuate with life stage, suggesting specific roles for them in biological and disease processes. We compared their non-genomic signa...
- Dual role of the arginine methyltransferase CARM1 in the regulation of c-Fos target genes
[作者:Fauquier, L; Duboe, C; Jore, C; Trouche, D; Vandel, L,期刊:FASEB Journal, 页码:3337-3347 , 文章类型: Article,,卷期:2008年22-9]
- Fos proteins, the prototypic members of basic region-leucine zipper ( bZIP) transcription factors, bind to other bZIP proteins to form the activator protein-1 (AP-1) complex, which regulates the expression of a plethora ...
- Human tumor nanoparticles induce apoptosis of pancreatic cancer cells
[作者:Ristorcelli, E; Beraud, E; Verrando, P; Villard, C; Lafitte, D; Sbarra, V; Lombardo, D; Verine, A,期刊:FASEB Journal, 页码:3358-3369 , 文章类型: Article,,卷期:2008年22-9]
- Exosomes are vesicles secreted by most hematopoietic cells on fusion of multivesicular endosomes with the plasma membrane. Many studies have reported that exosomes may also be released by tumor cells. Exosomes are believ...
- T-cell-mediated and antigen-dependent differentiation of human monocyte into different dendritic cell subsets: a feedback control of Th1/Th2 responses
[作者:Mariotti, S; Sargentini, V; Marcantonio, C; Todero, E; Teloni, R; Gagliardi, MC; Ciccaglione, AR; Nisini, R,期刊:FASEB Journal, 页码:3370-3379 , 文章类型: Article,,卷期:2008年22-9]
- It is well established that human monocytes differentiate into dendritic cells (DCs) when cultured with certain cytokine cocktails, such as granulocyte-macrophage colony-stimulating factor and interleukin-4. Conversely, ...
- A carbon monoxide-releasing molecule (CORM-3) abrogates polymorphonuclear granulocyte-induced activation of endothelial cells and mast cells
[作者:Masini, E; Vannacci, A; Failli, P; Mastroianni, R; Giannini, L; Vinci, MC; Uliva, C; Motterlini, R; Mannaioni, PF,期刊:FASEB Journal, 页码:3380-3388 , 文章类型: Article,,卷期:2008年22-9]
- We hypothesized that circulating polymorphonuclear granulocytes (PMNs), vascular endothelial cells (ECs), and perivascular mast cells (MCs) may initiate and sustain the inflammatory response through the generation of the...
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