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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue [作者：Qi, JZ; Gong, JY; Zhao, TJ; Zhao, J; Lam, P; Ye, J; Li, JZ; Wu, JW; Zhou, HM; Li, P,期刊：EMBO journal, 页码：1537-1548 , 文章类型： Article，,卷期：2008年27-11] We previously showed that Cidea(-/-)mice are resistant to diet-induced obesity through the upregulation of energy expenditure. The AMP-activated protein kinase (AMPK), consisting of catalytic a subunit and regulatory sub... FAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapse [作者：Bechara, A; Nawabi, H; Moret, F; Yaron, A; Weaver, E; Bozon, M; Abouzid, K; Guan, JL; Tessier-Lavigne, M; Lemmon, V; Castellani, V,期刊：EMBO journal, 页码：1549-1562 , 文章类型： Article，,卷期：2008年27-11] Axonal receptors for class 3 semaphorins (Sema3s) are heterocomplexes of neuropilins (Nrps) and Plexin-As signalling coreceptors. In the developing cerebral cortex, the Ig superfamily cell adhesion molecule L1 associates... Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation [作者：Weber, A; Marquardt, J; Elzi, D; Forster, N; Starke, S; Glaum, A; Yamada, D; Defossez, PA; Delrow, J; Eisenman, RN; Christiansen, H; Eilers, M,期刊：EMBO journal, 页码：1563-1574 , 文章类型： Article，,卷期：2008年27-11] In response to stimuli that activate p53, cells can undergo either apoptosis or cell cycle arrest, depending on the precise pattern of p53 target genes that is activated. We show here that Zbtb4, a transcriptional repres... Yeast Rap1 contributes to genomic integrity by activating DNA damage repair genes [作者：Tomar, RS; Zheng, S; Brunke-Reese, D; Wolcott, HN; Reese, JC,期刊：EMBO journal, 页码：1575-1584 , 文章类型： Article，,卷期：2008年27-11] Rap1 (repressor-activator protein 1) is a multifunctional protein that controls telomere function, silencing and the activation of glycolytic and ribosomal protein genes. We have identified a novel function for Rap1, reg... A Wingless and Notch double-repression mechanism regulates G1-S transition in the Drosophila wing [作者：Herranz, H; Perez, L; Martin, FA; Milan, M,期刊：EMBO journal, 页码：1633-1645 , 文章类型： Article，,卷期：2008年27-11] The control of tissue growth and patterning is orchestrated in various multicellular tissues by the coordinated activity of the signalling molecules Wnt/Wingless (Wg) and Notch, and mutations in these pathways can cause ... Inter-kingdom conservation of mechanism of nonsense-mediated mRNA decay [作者：Kerenyi, Z; Merai, Z; Hiripi, L; Benkovics, A; Gyula, P; Lacomme, C; Barta, E; Nagy, F; Silhavy, D,期刊：EMBO journal, 页码：1585-1595 , 文章类型： Article，,卷期：2008年27-11] Nonsense-mediated mRNA decay (NMD) is a quality control system that degrades mRNAs containing premature termination codons. Although NMD is well characterized in yeast and mammals, plant NMD is poorly understood. We have... 3 ' adenylation determines mRNA abundance and monitors completion of RNA editing in T-brucei mitochondria [作者：Etheridge, RD; Aphasizheva, I; Gershon, PD; Aphasizhev, R,期刊：EMBO journal, 页码：1596-1608 , 文章类型： Article，,卷期：2008年27-11] Expression of the mitochondrial genome in protozoan parasite Trypanosoma brucei is controlled post-transcriptionally and requires extensive U-insertion/deletion mRNA editing. In mitochondrial extracts, 3' adenylation rep... Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes [作者：Pisarev, AV; Kolupaeva, VG; Yusupov, MM; Hellen, CUT; Pestova, TV,期刊：EMBO journal, 页码：1609-1621 , 文章类型： Article，,卷期：2008年27-11] The position of mRNA on 40S ribosomal subunits in eukaryotic initiation complexes was determined by UV crosslinking using mRNAs containing uniquely positioned 4-thiouridines. Crosslinking of mRNA positions (+)11 to ribos... Molecular mechanism and structure of Trigger Factor bound to the translating ribosome [作者：Merz, F; Boehringer, D; Schaffitzel, C; Preissler, S; Hoffmann, A; Maier, T; Rutkowska, A; Lozza, J; Ban, N; Bukau, B; Deuerling, E,期刊：EMBO journal, 页码：1622-1632 , 文章类型： Article，,卷期：2008年27-11] Ribosome-associated chaperone Trigger Factor (TF) initiates folding of newly synthesized proteins in bacteria. Here, we pinpoint by site-specific crosslinking the sequence of molecular interactions of Escherichia coli TF...