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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共10条记录   The RNA acetyltransferase driven by ATP hydrolysis synthesizes N-4-acetylcytidine of tRNA anticodon [作者：Ikeuchi, Y; Kitahara, K; Suzuki, T,期刊：EMBO journal, 页码：2194-2203 , 文章类型： Article，,卷期：2008年27-16] The wobble base of Escherichia coli elongator tRNA(Met) is modified to N-4-acetylcytidine (ac(4)C), which is thought to ensure the precise recognition of the AUG codon by preventing misreading of near-cognate AUA codon. ... Dissecting beta-ring assembly pathway of the mammalian 20S proteasome [作者：Hirano, Y; Kaneko, T; Okamoto, K; Bai, M; Yashiroda, H; Furuyama, K; Kato, K; Tanaka, K; Murata, S,期刊：EMBO journal, 页码：2204-2213 , 文章类型： Article，,卷期：2008年27-16] The 20S proteasome is the catalytic core of the 26S proteasome. It comprises four stacked rings of seven subunits each, alpha(1-7)beta(1-7)beta(1-7)alpha(1-7). Recent studies indicated that proteasome-specific chaperones... Arabidopsis MAP kinase 4 regulates gene expression through transcription factor release in the nucleus [作者：Qiu, JL; Fiil, BK; Petersen, K; Nielsen, HB; Botanga, CJ; Thorgrimsen, S; Palma, K; Suarez-Rodriguez, MC; Sandbech-Clausen, S; Lichota, J; Brodersen, P; Grasser, KD; Mattsson, O; Glazebrook, J; Mundy, J; Petersen, M,期刊：EMBO journal, 页码：2214-2221 , 文章类型： Article，,卷期：2008年27-16] Plant and animal perception of microbes through pathogen surveillance proteins leads to MAP kinase signalling and the expression of defence genes. However, little is known about how plant MAP kinases regulate specific ge... DNA binding to RecD: role of the 1B domain in SF1B helicase activity [作者：Saikrishnan, K; Griffiths, SP; Cook, N; Court, R; Wigley, DB,期刊：EMBO journal, 页码：2222-2229 , 文章类型： Article，,卷期：2008年27-16] The molecular mechanism of superfamily 1B alpha helicases remains unclear. We present here the crystal structure of the RecD2 helicase from Deinococcus radiodurans at 2.2-angstrom resolution. The structure reveals the fo... Bacterial actin: architecture of the ParMRC plasmid DNA partitioning complex [作者：Salje, J; Lowe, J,期刊：EMBO journal, 页码：2230-2238 , 文章类型： Article，,卷期：2008年27-16] The R1 plasmid employs ATP-driven polymerisation of the actin-like protein ParM to move newly replicated DNA to opposite poles of a bacterial cell. This process is essential for ensuring accurate segregation of the low-c... Structure of the Roc-COR domain tandem of C-tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase [作者：Gotthardt, K; Weyand, M; Kortholt, A; Van Haastert, PJM; Wittinghofer, A,期刊：EMBO journal, 页码：2239-2249 , 文章类型： Article，,卷期：2008年27-16] Ras of complex proteins (Roc) belongs to the superfamily of Ras-related small G-proteins that always occurs in tandem with the C-terminal of Roc (COR) domain. This Roc-COR tandem is found in the bacterial and eukaryotic ... Cryo-electron microscopy reveals a novel DNA-binding site on the MCM helicase [作者：Costa, A; van Duinen, G; Medagli, B; Chong, J; Sakakibara, N; Kelman, Z; Nair, SK; Patwardhan, A; Onesti, S,期刊：EMBO journal, 页码：2250-2258 , 文章类型： Article，,卷期：2008年27-16] The eukaryotic MCM2-7 complex is recruited at origins of replication during the G1 phase and acts as the main helicase at the replication fork during the S phase of the cell cycle. To characterize the interplay between t... Structural basis for inhibition of homologous recombination by the RecX protein [作者：Ragone, S; Maman, JD; Furnham, N; Pellegrini, L,期刊：EMBO journal, 页码：2259-2269 , 文章类型： Article，,卷期：2008年27-16] The RecA/RAD51 nucleoprotein filament is central to the reaction of homologous recombination (HR). Filament activity must be tightly regulated in vivo as unrestrained HR can cause genomic instability. Our mechanistic und... Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling (vol 27, pg 1919, 2008) [作者：Ikenoue, T; Inoki, K; Yang, Q; Zhou, XM; Guan, KL,期刊：EMBO journal, 页码：2270-2270 , 文章类型： Correction，,卷期：2008年27-16] Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis [作者：Joshi, J; Fernandez-Marcos, PJ; Galvez, A; Amanchy, R; Linares, JF; Duran, A; Pathrose, P; Leitges, M; Canamero, M; Collado, M; Salas, C; Serrano, M; Moscat, J; Diaz-Meco, MT,期刊：EMBO journal, 页码：2181-2193 , 文章类型： Article，,卷期：2008年27-16] The atypical PKC-interacting protein, Par-4, inhibits cell survival and tumorigenesis in vitro, and its genetic inactivation in mice leads to reduced lifespan, enhanced benign tumour development and low-frequency carcino...