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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共12条记录   VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P-2 in yeast and mouse [作者：Jin, N; Chow, CY; Liu, L; Zolov, SN; Bronson, R; Davisson, M; Petersen, JL; Zhang, YL; Park, S; Duex, JE; Goldowitz, D; Meisler, MH; Weisman, LS,期刊：EMBO journal, 页码：3221-3234 , 文章类型： Article，,卷期：2008年27-24] The signalling lipid PI(3,5)P-2 is generated on endosomes and regulates retrograde traffic to the trans-Golgi network. Physiological signals regulate rapid, transient changes in PI(3,5)P-2 levels. Mutations that lower PI... Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly [作者：Tanenbaum, ME; Macrek, L; Galjart, N; Medema, RH,期刊：EMBO journal, 页码：3235-3245 , 文章类型： Article，,卷期：2008年27-24] Bipolar spindle assembly critically depends on the microtubule plus-end-directed motor Eg5 that binds antiparallel microtubules and slides them in opposite directions. As such, Eg5 can produce the necessary outward force... Control of WHITE COLLAR localization by phosphorylation is a critical step in the circadian negative feedback process [作者：Cha, J; Chang, SS; Huang, GC; Cheng, P; Liu, Y,期刊：EMBO journal, 页码：3246-3255 , 文章类型： Article，,卷期：2008年27-24] Reversible protein phosphorylation has critical functions in the eukaryotic circadian negative feedback loops. In Neurospora, the FREQUENCY protein closes the circadian negative feedback loop by promoting the phosphoryla... Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1 [作者：Yasukawa, T; Kamura, T; Kitajima, S; Conaway, RC; Conaway, JW; Aso, T,期刊：EMBO journal, 页码：3256-3266 , 文章类型： Article，,卷期：2008年27-24] The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II (pol II) by suppressing transient pausing of the pol II at many sites along the DNA. Elongin is composed of a transcriptionally act... Common thiolation mechanism in the biosynthesis of tRNA thiouridine and sulphur-containing cofactors [作者：Shigi, N; Sakaguchi, Y; Asai, S; Suzuki, T; Watanabe, K,期刊：EMBO journal, 页码：3267-3278 , 文章类型： Article，,卷期：2008年27-24] 2-Thioribothymidine (s(2)T), a modified uridine, is found at position 54 in transfer RNAs (tRNAs) from several thermophiles; s(2)T stabilizes the L-shaped structure of tRNA and is essential for growth at higher temperatu... Impediment of E. coli UvrD by DNA-destabilizing force reveals a strained-inchworm mechanism of DNA unwinding [作者：Sun, B; Wei, KJ; Zhang, B; Zhang, XH; Dou, SX; Li, M; Xi, XG,期刊：EMBO journal, 页码：3279-3287 , 文章类型： Article，,卷期：2008年27-24] Escherichia coli UvrD is a non-ring-shaped model helicase, displaying a 3'-5' polarity in DNA unwinding. Using a transverse magnetic tweezer and DNA hairpins, we measured the unwinding kinetics of UvrD at various DNA-des... A synaptic DEG/ENaC ion channel mediates learning in C. elegans by facilitating dopamine signalling [作者：Voglis, G; Tavernarakis, N,期刊：EMBO journal, 页码：3288-3299 , 文章类型： Article，,卷期：2008年27-24] An important component of learned behaviour is the ability to forecast positive or negative outcomes based on specific sensory cues. Predictive capacity is typically manifested by appropriate behavioural patterning. Howe... microRNA-122 stimulates translation of hepatitis C virus RNA [作者：Henke, JI; Goergen, D; Zheng, JF; Song, YT; Schuttler, CG; Fehr, C; Junemann, C; Niepmann, M,期刊：EMBO journal, 页码：3300-3310 , 文章类型： Article，,卷期：2008年27-24] Hepatitis C virus (HCV) is a positive strand RNA virus that propagates primarily in the liver. We show here that the liver-specific microRNA-122 (miR-122), a member of a class of small cellular RNAs that mediate post-tra... Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1 [作者：Terenzi, F; Saikia, P; Sen, GC,期刊：EMBO journal, 页码：3311-3321 , 文章类型： Article，,卷期：2008年27-24] Type I interferon (IFN) inhibits, by an unknown mechanism, the replication of human papillomaviruses (HPV), which are major human pathogens, Here, we present evidence that P56 (a protein), the expression of which is stro... Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM [作者：Li, W; Agirrezabala, X; Lei, JL; Bouakaz, L; Brunelle, JL; Ortiz-Meoz, RF; Green, R; Sanyal, S; Ehrenberg, M; Frank, J,期刊：EMBO journal, 页码：3322-3331 , 文章类型： Article，,卷期：2008年27-24] The accuracy of ribosomal translation is achieved by an initial selection and a proofreading step, mediated by EF-Tu, which forms a ternary complex with aminoacyl(aa)-tRNA. To study the binding modes of different aa-tRNA... EFC/F-BAR proteins and the N-WASP-WIP complex induce membrane curvature-dependent actin polymerization (vol 27, pg 2817, 2008) [作者：Takano, K; Toyooka, K; Suetsugu, S,期刊：EMBO journal, 页码：3332-3332 , 文章类型： Correction，,卷期：2008年27-24] Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration (vol 27, pg 3069, 2008) [作者：Blake, SM; Strasser, V; Andrade, N; Duit, S; Hofbauer, R; Schneider, WJ; Nimpf, J,期刊：EMBO journal, 页码：3332-3332 , 文章类型： Correction，,卷期：2008年27-24]