- Credneramides A and B: Neuromodulatory Phenethylamine and Isopentylamine Derivatives of a Vinyl Chloride-Containing Fatty Acid from cf. Trichodesmium sp nov.
[作者:Malloy, KL; Suyama, TL; Engene, N; Debonsi, H; Cao, ZY; Matainaho, T; Spadafora, C; Murray, TF; Gerwick, WH,期刊:Journal of natural products, 页码:60-66 , 文章类型: Article,,卷期:2012年75-1]
- Credneramides A (1) and B (2), two vinyl chloride-containing metabolites, were isolated from a Papua New Guinea collection of cf. Trichodesmium sp. nov. and expand a recently described class of vinyl chloride-containing ...
- Anti-inflammatory Mechanism of 15,16-Epoxy-3 alpha-hydroxylabda-8,13(16),14-trien-7-one via Inhibition of LPS-Induced Multicellular Signaling Pathways
[作者:Khan, S; Shehzad, O; Jin, HG; Woo, ER; Kang, SS; Baek, SW; Kim, J; Kim, YS,期刊:Journal of natural products, 页码:67-71 , 文章类型: Article,,卷期:2012年75-1]
- Phytochemical investigation of Leonurus japonicus has led to the isolation of a labdane diterpene derivative, 15,16-epoxy-3 alpha-hydroxylabda-8,13(16),14-trien-7-one (1), which was tested for its in vitro anti-inflammat...
- Drug-like Properties: Guiding Principles for the Design of Natural Product Libraries
[作者:Camp, D; Davis, RA; Campitelli, M; Ebdon, J; Quinn, RJ,期刊:Journal of natural products, 页码:72-81 , 文章类型: Article,,卷期:2012年75-1]
- While natural products or their derivatives and mimics have contributed around 50% of current drugs, there has been no approach allowing front-loading of chemical space compliant with lead- and drug-like properties. The ...
- 2-Arylbenzofuran, Flavonoid, and Tyrosinase Inhibitory Constituents of Morus yunnanensis
[作者:Hu, X; Wu, JW; Wang, M; Yu, MH; Zhao, QS; Wang, HY; Hou, AJ,期刊:Journal of natural products, 页码:82-87 , 文章类型: Article,,卷期:2012年75-1]
- Two novel 2-arylbenzofuran dimers, morusyunnansins A and B (1 and 2), two new biflavonoids, morusyunnansins C and D (3 and 4), two new flavans, morusyunnansins E and F (5 and 6), and four known flavans (7-10) were isolat...
- Benzyl Benzoate Glycoside and 3-Deoxy-D-manno-2-octulosonic Acid Derivatives from Solidago decurrens
[作者:Shiraiwa, K; Yuan, S; Fujiyama, A; Matsuo, Y; Tanaka, T; Jiang, ZH; Kouno, I,期刊:Journal of natural products, 页码:88-92 , 文章类型: Article,,卷期:2012年75-1]
- A new benzyl benzoate glycoside and five new 3-deoxy-D-manno-2-octulosonic acid derivatives were isolated from the entire plant of Solidago decurrens together with three known compounds. Their structures were established...
- Dihydroagarofuran Derivatives from the Dried Roots of Tripterygium wilfordii
[作者:Luo, YG; Zhou, M; Ye, Q; Pu, Q; Zhang, GL,期刊:Journal of natural products, 页码:98-102 , 文章类型: Article,,卷期:2012年75-1]
- Five new sesquiterpene derivatives, including dihydroagarofuran pyridine macrolides 1-4 and dihydroagarofuran ester 18, and 13 known dihydroagarofuran derivatives were isolated from the aqueous EtOH extract of the dried ...
- Cerinolactone, a Hydroxy-Lactone Derivative from Trichoderma cerinum
[作者:Vinale, F; Girona, IA; Nigro, M; Mazzei, P; Piccolo, A; Ruocco, M; Woo, S; Rosa, DR; Herrera, CL; Lorito, M,期刊:Journal of natural products, 页码:103-106 , 文章类型: Article,,卷期:2012年75-1]
- A novel metabolite, 3-hydroxy-5-(6-isopropyl-3-methylene-3,4,4a,5,6,7,8,8a-octahydronaphthalen-2-yl)dihydrofuran-2-one, trivially named cerinolactone (1), has been isolated from culture filtrates of Trichoderma cerinum t...
- JBIR-94 and JBIR-125, Antioxidative Phenolic Compounds from Streptomyces sp R56-07
[作者:Kawahara, T; Izumikawa, M; Otoguro, M; Yamamura, H; Hayakawa, M; Takagi, M; Shin-ya, K,期刊:Journal of natural products, 页码:107-110 , 文章类型: Article,,卷期:2012年75-1]
- Two phenolic compounds, JBIR-94 (1) and JBIR-125 (2), were isolated from the fermentation broth of strain R56-07, which was identified by phylogenetic methods as a novel species of Streptomyces. The structures of 1 and 2...
- Gliotoxin Analogues from a Marine-Derived Fungus, Penicillium sp., and Their Cytotoxic and Histone Methyltransferase Inhibitory Activities
[作者:Sun, Y; Takada, K; Takemoto, Y; Yoshida, M; Nogi, Y; Okada, S; Matsunaga, S,期刊:Journal of natural products, 页码:111-114 , 文章类型: Article,,卷期:2012年75-1]
- Seven gliotoxin-related compounds were isolated from the fungus Penicillium sp. strain JMF034, obtained from deep sea sediments of Suruga Bay, Japan. These included two new metabolites, bis(dethio)-10a-methylthio-3a-deox...
- Dactylomelatriol, a Biogenetically Intriguing Omphalane-Derived Marine Sesquiterpene
[作者:Diaz-Marrero, AR; de la Rosa, JM; Brito, I; Darias, J; Cueto, M,期刊:Journal of natural products, 页码:115-118 , 文章类型: Article,,卷期:2012年75-1]
- Dactylomelatriol (1), obtained from the sea hare Aplysia dactylomela, is the first naturally occurring omphalane-derived sesquiterpene from the marine environment. From this species the known chamigrene and modified bisa...
- Sesquiterpene Lactones from Anthemis melanolepis and Their Antibacterial and Cytotoxic Activities. Prediction of Their Pharmacokinetic Profile (vol 73, pg 242, 2010)
[作者:Saroglou, V; Karioti, A; Rancic, A; Dimas, K; Koukoulitsa, C; Zervou, M; Skaltsa, H,期刊:Journal of natural products, 页码:119-119 , 文章类型: Correction,,卷期:2012年75-1]
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- Chromophenazines from the Terrestrial Streptomyces sp Ank 315
[作者:Zendah, I; Riaz, N; Nasr, H; Frauendorf, H; Schuffler, A; Raies, A; Laatsch, H,期刊:Journal of natural products, 页码:2-8 , 文章类型: Article,,卷期:2012年75-1]
- The new chromophenazines A-F [9-methyl-5-(3'-methylbut-2'-enyl)-5H-benzo[a]phenazin-7-one (la), 9-methyl-5-(3'-methylbut-2'-enyl)-7-oxo-5,7-dihydrobenzo [a]phenazine-1-carboxylic acid (1b), 5-(3'-methylbut-2'-eny1)-7-oxo...
- Induction of Apoptosis in HL-60 Cells through the ROS-Mediated Mitochondrial Pathway by Ramentaceone from Drosera aliciae
[作者:Kawiak, A; Zawacka-Pankau, J; Wasilewska, A; Stasilojc, G; Bigda, J; Lojkowska, E,期刊:Journal of natural products, 页码:9-14 , 文章类型: Article,,卷期:2012年75-1]
- Ramentaceone (1) is a naphthoquinone constituent of Drosera aliciae that exhibits potent cytotoxic activity against various tumor cell lines. However, its molecular mechanism of cell death induction has still not been de...
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