- Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome
[作者：Moretti, A; Bellin, M; Welling, A; Jung, CB; Lam, JT; Bott-Flugel, L; Dorn, T; Goedel, A; Hohnke, C; Hofmann, F; Seyfarth, M; Sinnecker, D; Schomig, A; Laugwitz, KL,期刊：New England Journal of Medicine, 页码：1397-1409 , 文章类型： Article，,卷期：2010年363-15]
- Background: Long-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia. In long-QT syndrome...
- Severe Hypoglycemia and Risks of Vascular Events and Death
[作者：Zoungas, S; Patel, A; Chalmers, J; de Galan, BE; Li, QA; Billot, L; Woodward, M; Ninomiya, T; Neal, B; MacMahon, S; Grobbee, DE; Kengne, AP; Marre, M; Heller, S,期刊：New England Journal of Medicine, 页码：1410-1418 , 文章类型： Article，,卷期：2010年363-15]
- Background: Severe hypoglycemia may increase the risk of a poor outcome in patients with type 2 diabetes assigned to an intensive glucose-lowering intervention. We analyzed data from a large study of intensive glucose lo...
- Rolofylline, an Adenosine A(sub 1)-Receptor Antagonist, in Acute Heart Failure
[作者：Massie, BM; O'Connor, CM; Metra, M; Ponikowski, P; Teerlink, JR; Cotter, G; Weatherley, BD; Cleland, JGF; Givertz, MM; Voors, A; DeLucca, P; Mansoor, GA; Salerno, CM; Bloomfield, DM; Dittrich, HC,期刊：New England Journal of Medicine, 页码：1419-1428 , 文章类型： Article，,卷期：2010年363-15]
- Background: Worsening renal function, which is associated with adverse outcomes, often develops in patients with acute heart failure. Experimental and clinical studies suggest that counterregulatory responses mediated by...
- Brief Report: Dystrophin Immunity in Duchenne's Muscular Dystrophy
[作者：Mendell, JR; Campbell, K; Rodino-Klapac, L; Sahenk, Z; Shilling, C; Lewis, S; Bowles, D; Gray, S; Li, CW; Galloway, G; Malik, V; Coley, B; Clark, KR; Li, JA; Xiao, XA; Samulski, J; McPhee, SW; Samulski, RJ; Walker, CM,期刊：New England Journal of Medicine, 页码：1429-1437 , 文章类型： Article，,卷期：2010年363-15]
- We report on delivery of a functional dystrophin transgene to skeletal muscle in six patients with Duchenne's muscular dystrophy. Dystrophin-specific T cells were detected after treatment, providing evidence of transgene...
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