- Recent Advances in Molecular Approaches to Gut Microbiota in Inflammatory Bowel Disease
[作者:Andoh, A; Benno, Y; Kanauchi, O; Fujiyama, Y,期刊:Current Pharmaceutical Design, 页码:2066-2073 , 文章类型: Review,,卷期:2009年15-18]
Inflammatory bowel diseases [IBD], ulcerative colitis [UC] and Crohn's disease [CD], are chronic intestinal disorders of unknown etiology. UC and CD are heterogeneous diseases characterized by various genetic abnormal...
- Recent Understanding of Leukocytapheresis (LCAP) for the Treatment of Inflammatory Bowel Disease
[作者:Mitsuyama, K; Yamasaki, H; Kuwaki, K; Takedatsu, H; Sata, M,期刊:Current Pharmaceutical Design, 页码:2110-2119 , 文章类型: Review,,卷期:2009年15-18]
- Inflammatory bowel disease (IBD) is frequently associated with the infiltration of a large number of leukocytes into the bowel mucosa. Therefore, the removal of circulating leukocytes may be an attractive approach for th...
- HCN Pacemaker Channels and Pain: A Drug Discovery Perspective
[作者:Wickenden, AD; Maher, MP; Chaplan, SR,期刊:Current Pharmaceutical Design, 页码:2149-2168 , 文章类型: Review,,卷期:2009年15-18]
- This article reviews evidence that hyperpolarization-activated, cation nonselective (HCN) channels, the molecular basis of the I-h current, potentially represent valid targets for novel analgesic agents. I-h is a promine...
- The Intestinal Environment in Health and Disease - Recent Insights on the Potential of Intestinal Bacteria to Influence Human Health
[作者:Possemiers, S; Grootaert, C; Vermeiren, J; Gross, G; Marzorati, M; Verstraete, W; Van de Wiele, T,期刊:Current Pharmaceutical Design, 页码:2051-2065 , 文章类型: Review,,卷期:2009年15-18]
- The human intestine is colonized by a complex microbial ecosystem, which could be considered as a separate organ within the human host, having a coding capacity which exceeds the liver by a factor 100. On the one hand, t...
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