- Function and Frustration of Multi-Drug ABC Exporter Protein and Design of Model Proteins for Drug Delivery Using Protein Hydration Thermodynamics
[作者:Urry, DW; Urry, KD; Szaflarski, W; Nowicki, M; Zabel, M,期刊:Current Pharmaceutical Design, 页码:2833-2867 , 文章类型: Review,,卷期:2009年15-24]
- The mechanism is presented whereby simultaneous hydrolysis of two molecules of ATP in the ATP-binding cassette (ABC) exporter protein, Sav 1866, opens a transmembrane channel to pump drug out of the cell and confers drug...
- Therapeutic Neovascularization by the Implantation of Autologous Mononuclear Cells in Patients with Connective Tissue Diseases
[作者:Takahashi, M; Izawa, A; Ishigatsubo, Y; Fujimoto, K; Miyamoto, M; Horie, T; Aizawa, Y; Amano, J; Minota, S; Murohara, T; Matsubara, H; Ikeda, U,期刊:Current Pharmaceutical Design, 页码:2778-2783 , 文章类型: Review,,卷期:2009年15-24]
- Vasculopathy in patients with connective tissue diseases (CTDs), including systemic sclerosis (SSc) and systemic lupus erythematosus (SLE), is a serious complication that mainly affects small arteries and capillaries, re...
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