- Protein kinase C beta II and delta/theta play critical roles in bone morphogenic protein-4-stimulated osteoblastic differentiation of MC3T3-E1 cells
[作者:Park, KH; Han, DI; Rhee, YH; Jeong, SJ; Kim, SH; Park, YG,期刊:Biochemical and Biophysical Research Communications, 页码:7-12 , 文章类型: Article,,卷期:2010年403-1]
- Bone morphogenic protein-4 (BMP-4), one of TGF-beta superfamily, is involved in bone and cartilage development, specifically tooth and bone fracture repair. In the present study, the role of protein kinase C (PKC) was in...
- p73 regulates maintenance of neural stem cell
[作者:Agostini, M; Tucci, P; Chen, HL; Knight, RA; Bano, D; Nicotera, P; McKeon, F; Melino, G,期刊:Biochemical and Biophysical Research Communications, 页码:13-17 , 文章类型: Article,,卷期:2010年403-1]
- p73, a member of the p53 family, is a transcription factor that plays a key role in many biological processes. In the present study, we show that TAp73 is expressed in neural stem cells (NSC) and its expression increases...
- Gsdma3 is required for hair follicle differentiation in mice
[作者:Li, J; Zhou, Y; Yang, TA; Wang, N; Lian, XH; Yang, L,期刊:Biochemical and Biophysical Research Communications, 页码:18-23 , 文章类型: Article,,卷期:2010年403-1]
- Hair follicle differentiation is regulated by multiple signaling pathways. However, the known cellular and molecular mechanisms are limited. Gsdma3 is a novel murine gene and considered to be a mutation hotspot. Six muta...
- Ghrelin inhibits proliferation and increases T-type Ca2+ channel expression in PC-3 human prostate carcinoma cells
[作者:Diaz-Lezama, N; Hernandez-Elvira, M; Sandoval, A; Monroy, A; Felix, R; Monjaraz, E,期刊:Biochemical and Biophysical Research Communications, 页码:24-29 , 文章类型: Article,,卷期:2010年403-1]
- Ghrelin is a multifunctional peptide hormone with roles in growth hormone release, food intake and cell proliferation. With ghrelin now recognized as important in neoplastic processes, the aim of this report is to presen...
- Heme controls the regulation of protein tyrosine kinases Jak2 and Src
[作者:Yao, XA; Balamurugan, P; Arvey, A; Leslie, C; Zhang, L,期刊:Biochemical and Biophysical Research Communications, 页码:30-35 , 文章类型: Article,,卷期:2010年403-1]
- Protein tyrosine kinases play key roles in many molecular and cellular processes in diverse living organisms. Their proper functioning is crucial for the normal growth, development, and health in humans, whereas their dy...
- The relationship between GPR40 and lipotoxicity of the pancreatic beta-cells as well as the effect of pioglitazone
[作者:Wu, PW; Yang, LY; Shen, XM,期刊:Biochemical and Biophysical Research Communications, 页码:36-39 , 文章类型: Article,,卷期:2010年403-1]
- Free fatty acids (FFAs) acutely stimulate insulin secretion from pancreatic beta-cells, whereas impair beta-cell function following long term exposure. GPR40, a FFAs receptor, has been demonstrated to be activated by bot...
- Identification of a novel Vpr-binding compound that inhibits HIV-1 multiplication in macrophages by chemical array
[作者:Hagiwara, K; Murakami, T; Xue, GG; Shimizu, Y; Takeda, E; Hashimoto, Y; Honda, K; Kondoh, Y; Osada, H; Tsunetsugu-Yokota, Y; Aida, Y,期刊:Biochemical and Biophysical Research Communications, 页码:40-45 , 文章类型: Article,,卷期:2010年403-1]
- Although HIV-1 replication can be controlled by highly active anti-retroviral therapy (HAART) using protease and reverse transcriptase inhibitors, the development of multidrug-resistant viruses compromises the efficacy o...
- Static pressure accelerates ox-LDL-induced cholesterol accumulation via SREBP-1-mediated caveolin-1 downregulation in cultured vascular smooth muscle cells
[作者:Luo, DX; Xia, CL; Li, JM; Xiong, Y; Yuan, HY; Tang, ZW; Zeng, YX; Liao, DF,期刊:Biochemical and Biophysical Research Communications, 页码:52-58 , 文章类型: Article,,卷期:2010年403-1]
- Objective: To investigate the effect of static pressure on cholesterol accumulation in vascular smooth muscle cells (VSMCs) and its mechanism. Methods: Rat-derived VSMC cell line A10 treated with 50 mg/L ox-LDL and diffe...
- Angiogenic role of orexin-A via the activation of extracellular signal-regulated kinase in endothelial cells
[作者:Kim, MK; Park, HJ; Kim, SR; Choi, YK; Shin, HK; Jeon, JH; Jang, HO; Yun, I; Bae, SK; Bae, MK,期刊:Biochemical and Biophysical Research Communications, 页码:59-65 , 文章类型: Article,,卷期:2010年403-1]
- Orexin-A, a neuropeptide originally discovered in the hypothalamus, is found in peripheral organs, as well as in the central nervous system, and is involved in the regulation of food intake, energy homeostasis, and cardi...
- Effects of long term nitrite therapy on functional recovery in experimental ischemia model
[作者:Jung, KH; Chu, K; Lee, ST; Sunwoo, JS; Park, DK; Kim, JH; Kim, S; Lee, SK; Kim, M; Roh, JK,期刊:Biochemical and Biophysical Research Communications, 页码:66-72 , 文章类型: Article,,卷期:2010年403-1]
- Our data have shown that nitrite therapy can rescue the ischemic brain when injected <3 h after cerebral ischemic-reperfusion (I/R) injury and its effects can be prolonged to 4.5 h in combination with memantine. We inves...
- ATP6v0d2 deficiency increases bone mass, but does not influence ovariectomy-induced bone loss
[作者:Kim, T; Ha, H; Kim, N; Park, ES; Rho, J; Kim, EC; Lorenzo, J; Choi, Y; Lee, SH,期刊:Biochemical and Biophysical Research Communications, 页码:73-78 , 文章类型: Article,,卷期:2010年403-1]
- Bone homeostasis is maintained through the balanced action of bone-forming osteoblasts and bone-resorbing osteoclasts. Under pathological conditions or with age, excessive bone loss is often observed due to increased bon...
- Dissecting the cosubstrate structure requirements of the Staphylococcus aureus aminoglycoside resistance enzyme ANT(4 ')
[作者:Porter, VR; Green, KD; Zolova, OE; Houghton, JL; Garneau-Tsodikova, S,期刊:Biochemical and Biophysical Research Communications, 页码:85-90 , 文章类型: Article,,卷期:2010年403-1]
- Aminoglycosides are important antibiotics used against a wide range of pathogens. As a mechanism of defense, bacteria have evolved enzymes able to inactivate these drugs by regio-selectively adding a variety of functiona...
|