- The CRL2(LRR-1) ubiquitin ligase regulates cell cycle progression during C. elegans development
[作者:Merlet, J; Burger, J; Tavernier, N; Richaudeau, B; Gomes, JE; Pintard, L,期刊:Development, 页码:3857-3866 , 文章类型: Article,,卷期:2010年137-22]
- The molecular mechanisms that regulate cell cycle progression in a developmental context are poorly understood. Here, we show that the leucine-rich repeat protein LRR-1 promotes cell cycle progression during C. elegans d...
- A dual role for ErbB2 signaling in cardiac trabeculation
[作者:Liu, JD; Bressan, M; Hassel, D; Huisken, J; Staudt, D; Kikuchi, K; Poss, KD; Mikawa, T; Stainier, DYR,期刊:Development, 页码:3867-3875 , 文章类型: Article,,卷期:2010年137-22]
- Cardiac trabeculation is a crucial morphogenetic process by which clusters of ventricular cardiomyocytes extrude and expand into the cardiac jelly to form sheet-like projections. Although it has been suggested that cardi...
- Diffusion-based DNA target colocalization by thermodynamic mechanisms
[作者:Scialdone, A; Nicodemi, M,期刊:Development, 页码:3877-3885 , 文章类型: Article,,卷期:2010年137-22]
- In eukaryotic cell nuclei, a variety of DNA interactions with nuclear elements occur, which, in combination with intra- and inter-chromosomal cross-talks, shape a functional 3D architecture. In some cases they are organi...
- Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation
[作者:Gordon, EJ; Rao, S; Pollard, JW; Nutt, SL; Lang, RA; Harvey, NL,期刊:Development, 页码:3899-3910 , 文章类型: Article,,卷期:2010年137-22]
- Macrophages have been suggested to stimulate neo-lymphangiogenesis in settings of inflammation via two potential mechanisms: (1) acting as a source of lymphatic endothelial progenitor cells via the ability to transdiffer...
- RPK2 is an essential receptor-like kinase that transmits the CLV3 signal in Arabidopsis
[作者:Kinoshita, A; Betsuyaku, S; Osakabe, Y; Mizuno, S; Nagawa, S; Stahl, Y; Simon, R; Yamaguchi-Shinozaki, K; Fukuda, H; Sawa, S,期刊:Development, 页码:3911-3920 , 文章类型: Article,,卷期:2010年137-22]
- The shoot apical meristem (SAM) is the fundamental structure that is located at the growing tip and gives rise to all aerial parts of plant tissues and organs, such as leaves, stems and flowers. In Arabidopsis thaliana, ...
- Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors
[作者:Parsa, S; Kuremoto, K; Seidel, K; Tabatabai, R; MacKenzie, B; Yamaza, T; Akiyama, K; Branch, J; Koh, CJ; Al Alam, D; Klein, OD; Bellusci, S,期刊:Development, 页码:3743-3752 , 文章类型: Article,,卷期:2010年137-22]
- Rodent incisors regenerate throughout the lifetime of the animal owing to the presence of epithelial and mesenchymal stem cells in the proximal region of the tooth. Enamel, the hardest component of the tooth, is continuo...
- Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor
[作者:Seidel, K; Ahn, CP; Lyons, D; Nee, A; Ting, K; Brownell, I; Cao, T; Carano, RAD; Curran, T; Schober, M; Fuchs, E; Joyner, A; Martin, GR; de Sauvage, FJ; Klein, OD,期刊:Development, 页码:3753-3761 , 文章类型: Article,,卷期:2010年137-22]
- In many organ systems such as the skin, gastrointestinal tract and hematopoietic system, homeostasis is dependent on the continuous generation of differentiated progeny from stem cells. The rodent incisor, unlike human t...
- Changes in the nuclear deposition of histone H2A variants during pre-implantation development in mice
[作者:Nashun, B; Yukawa, M; Liu, HL; Akiyama, T; Aoki, F,期刊:Development, 页码:3785-3794 , 文章类型: Article,,卷期:2010年137-22]
- Histone H2A has several variants, and changes in chromatin composition associated with their replacement might involve chromatin structure remodeling. We examined the dynamics of the canonical histone H2A and its three v...
- Hox11 genes establish synovial joint organization and phylogenetic characteristics in developing mouse zeugopod skeletal elements
[作者:Koyama, E; Yasuda, T; Minugh-Purvis, N; Kinumatsu, T; Yallowitz, AR; Wellik, DM; Pacifici, M,期刊:Development, 页码:3795-3800 , 文章类型: Article,,卷期:2010年137-22]
- Hox11 genes are essential for zeugopod skeletal element development but their roles in synovial joint formation remain largely unknown. Here, we show that the elbow and knee joints of mouse embryos lacking all Hox11 para...
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