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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共20条记录   A Practical and Efficient Total Synthesis of Potent Insulinotropic (2S,3R,4S)-4-Hydroxyisoleucine through a Chiral N-Protected gamma-Keto-alpha-aminoester [作者：MARIN SANDRA DE LAMO; CATALA CEDRIC; KUMAR SREEKANTHA RATNA; VALLEIX ALAIN; WAGNER ALAIN; MIOSKOWSKI CHARLES,期刊：European Journal of Organic Chemistry, 页码：3985-3989 , 文章类型： Article，,卷期：2010年-21] (2S,3R,4S)-4-Hydroxyisoleucine, which exhibits remarkable insulinotropic activity, is expected to be a potent drug to treat type II diabetes. We propose herein a four-step synthesis of the enantiopure natural product on ... Convergent Synthesis and Biological Evaluation of Syringolin A and Derivatives as Eukaryotic 20S Proteasome Inhibitors [作者：CLERC JEROME; SCHELLENBERG BARBARA; GROLL MICHAEL; BACHMANN ANDRE S; HUBER ROBERT; DUDLER ROBERT; KAISER MARKUS,期刊：European Journal of Organic Chemistry, 页码：3991-4003 , 文章类型： Article，,卷期：2010年-21] A convergent synthesis of SylA was developed and consists of the synthesis of a fully functionalized macrocycle, which is subsequently coupled with a urea moiety. For cyclization, ring-closing metathesis of a conformatio... A Joint Experimental and Theoretical Investigation on Nonlinear Optical (NLO) Properties of a New Class of Push-Pull Spirobifluorene Compounds [作者：RIZZO FABIO; CAVAZZINI MARCO; RIGHETTO STEFANIA; DE ANGELIS FILIPPO; FANTACCI SIMONA; QUICI SILVIO,期刊：European Journal of Organic Chemistry, 页码：4004-4016 , 文章类型： Article，,卷期：2010年-21] A new class of push-pull spirobifluorene compounds 1-5 has been synthesized. The nonlinear optical (NLO) properties (first and second hyperpolarizability beta and gamma, respectively) of spirobifluorene derivatives have ... A General Methodology for the Enantioselective Synthesis of 1-Substituted Tetrahydroisoquinoline Alkaloids [作者：AMAT MERCEDES; ELIAS VIVIANE; LLOR NURIA; SUBRIZI FABIANA; MOLINS ELIES; BOSCH JOAN,期刊：European Journal of Organic Chemistry, 页码：4017-4026 , 文章类型： Article，,卷期：2010年-21] Starting from tricyclic lactam 2, which is easily accessible by cyclocondensation of delta-oxoester 1 with (R)-phenylglycinol, a three-step synthetic route to enantiopure 1-substituted tetra-hydroisoquinolines, including... The Chemical Behavior of 3,4-Benzocycloocten-1,5-diyne [作者：WERNER CHRISTIAN; HOPF HENNING; GRUNENBERG JOERG; JONES PETER G,期刊：European Journal of Organic Chemistry, 页码：4027-4034 , 文章类型： Article，,卷期：2010年-21] The title compound 3,4-benzocycloocten-1,5-diyne (1) is a highly reactive hydrocarbon that has been shown to undergo addition reactions with tetraphenyl-cyclopentadienone (tetracyclone) to the 2:1 adduct 6, with octacarb... Preparation of Highly Hindered Polyenynes [作者：KILICKIRAN PINAR; HOPF HENNING; DIX INA; JONES PETER G,期刊：European Journal of Organic Chemistry, 页码：4035-4045 , 文章类型： Article，,卷期：2010年-21] The terminal enynes 10-12 were prepared from the corresponding aldehydes 6-8 by applying conventional methods of acetylene chemistry. After exploratory study of the reactivity of these hydrocarbons (preparation of 13, 18... Preparation and Structure Determination of a Stable cis-Bis-sigma-homobenzene Derivative [作者：WULLBRANDT DIETER; HOPF HENNING; JONES PETER G,期刊：European Journal of Organic Chemistry, 页码：4046-4048 , 文章类型： Article，,卷期：2010年-21] By cyclopropanation of tetramethyl[2,2]paracyclophane 9 the tetramethylene adduct 10 has been prepared. This hydrocarbon is the first stable cis-bis-sigma-homobenzene for which a structure has been determined by X-ray di... Synthesis of a C-3-Symmetric Furyl-Cyclopeptide Platform with Anion Recognition Properties [作者：MOLINA LIDIA; MORENOCAVIJO ELENA; MORENOVARGAS ANTONIO J; CARMONA ANA T; ROBINA INMACULADA,期刊：European Journal of Organic Chemistry, 页码：4049-4055 , 文章类型： Article，,卷期：2010年-21] A new furyl amino acid derivative was trimerized to give a linear peptide and finally was cyclized. The newly generated cyclopeptide was subjected to a conformational study in order to be considered as a C-3-symmetric pl... Imidate-Phosphanes as Highly Versatile N,P Ligands and Their Application in Palladium-Catalyzed Asymmetric Allylic Alkylation Reactions [作者：NOEL TIMOTHY; BERT KATRIEN; VAN DER EYCKEN ERIK; VAN DER EYCKEN JOHAN,期刊：European Journal of Organic Chemistry, 页码：4056-4061 , 文章类型： Article，,卷期：2010年-21] Chiral imidate-phosphanes were developed as a new type of N,P ligands. These ligands are easily accessible through a one-step procedure starting from a commercially available chiral aminophosphane and an imidate precurso... A Urea-Linked Glucosamine Dimer as a Building Block for the Synthesis of Linear and Cyclic Neosaccharides [作者：CIRILLO LUIGI; SILIPO ALBA; BEDINI EMILIANO; PARRILLI MICHELANGELO,期刊：European Journal of Organic Chemistry, 页码：4062-4074 , 文章类型： Article，,卷期：2010年-21] A novel urea-linked glucosamine dimer was obtained through a modification of the standard oxazolidinone closure reaction on a 2,3-amino alcohol monomer and fully characterized by NMR spectroscopy and by molecular mechani... Stereocontrolled Synthesis of the Highly Functionalized Core Structure of Aurisides by Ring-Closing Metathesis [作者：BOURCET EMMANUEL; FACHE FABIENNE; PIVA OLIVIER,期刊：European Journal of Organic Chemistry, 页码：4075-4087 , 文章类型： Article，,卷期：2010年-21] Two approaches based on the ring-closing metathesis reaction have been explored for the synthesis of the core structure of the marine natural products, the aurisides. The second approach, accomplished in a stereocontroll... Aza-Michael Addition Reactions of Hydrazones with Activated Alkynes Catalyzed by Nitrogen-Containing Organic Bases [作者：YUAN ZHILIANG; WEI YIN; SHI MIN,期刊：European Journal of Organic Chemistry, 页码：4088-4097 , 文章类型： Article，,卷期：2010年-21] Several highly efficient DABCO (1,4-diazabicyclo[2.2.2]-octane)-catalyzed Michael-type reactions of hydrazones with activated alkynes are described in this paper. This aza-Michael addition reaction can be applied to diff... Asymmetric Aza-Morita-Baylis-Hillman Reactions of Alkyl Vinyl Ketones with N-Protected Imines or In Situ Generated N-Protected Imines [作者：GUAN XIAOYANG; WEI YIN; SHI MIN,期刊：European Journal of Organic Chemistry, 页码：4098-4105 , 文章类型： Article，,卷期：2010年-21] DABCO-catalyzed aza-MBH reactions of N-Boc imines with MVK and EVK have been thoroughly investigated in the paper. The asymmetric version of this aza-MBH reaction was also systematically investigated by using a chiral am... HOTf-Catalyzed Rearrangement of Methylenecyclopropane Aryl and Alkyl Alcohols [作者：TANG XIANGYING; SHI MIN,期刊：European Journal of Organic Chemistry, 页码：4106-4110 , 文章类型： Article，,卷期：2010年-21] An efficient method to synthesize multisubstituted naphthalene and cyclobutanol derivatives through ring opening/ring enlargement of readily available methylenecyclopropane diaryl alcohols or dialkyl- and monoalkyl- as w... 1,2-Oxazines as Building Blocks for Stereoselective Synthesis: Preparation of Oxygen-Substituted 1,2-Oxazines, either by Alcohol Addition or by Epoxidation, and Subsequent Hydrogenation Leading to 1,2-Amino Alcohols and Pyrrolidines [作者：ZIMMER REINHOLD; BUCHHOLZ MONIKA; COLLAS MARKUS; ANGERMANN JOERG; HOMANN KAI; REISSIG HANSULRICH,期刊：European Journal of Organic Chemistry, 页码：4111-4121 , 文章类型： Article，,卷期：2010年-21] Stereodefined oxygen-substituted 1,2-oxazines were prepared by three different routes. The cycloaddition of enol ethers such as 1 with alpha-nitrosoalkenes generated in situ gave the heterocycles 3 and 4. Acid-catalysed ... Synthetic Exploration of Oxacalix[2]arene[2]quinazolines [作者：VAN ROSSOM WIM; KISHORE LINGAM; ROBEYNS KOEN; VAN MEERVELT LUC; DEHAEN WIM; MAES WOUTER,期刊：European Journal of Organic Chemistry, 页码：4122-4129 , 文章类型： Article，,卷期：2010年-21] Oxacalix[2]arene[2]quinazoline macrocycles were prepared in good yields, as mixtures of syn and anti isomers, through nucleophilic aromatic substitution cyclocondensation reactions of 2,4-dichloroquinazolines and m-dihyd...