- Albumin-based nanoparticles as potential controlled release drug delivery systems
[作者:Elzoghby, AO; Samy, WM; Elgindy, NA,期刊:Journal of controlled release, 页码:168-182 , 文章类型: Review,,卷期:2012年157-2]
- Albumin, a versatile protein carrier for drug delivery, has been shown to be nontoxic, non-immunogenic, biocompatible and biodegradable. Therefore, it is ideal material to fabricate nanoparticles for drug delivery. Album...
- In vivo antitumor effect of cromolyn in PEGylated liposomes for pancreatic cancer
[作者:Kim, CE; Lim, SK; Kim, JS,期刊:Journal of controlled release, 页码:190-195 , 文章类型: Article,,卷期:2012年157-2]
- A PEGylated liposomal formulation of cromolyn, composed of dipalmitoylphosphatidylcholine (DPPC), dimyristoylphosphatidylcholine (DMPC), distearoylphosphatidylcholine (DSPC) and 1,2-distearoyl-sn-glycero-3-phospho-ethano...
- Improved in vivo delivery of m-THPC via pegylated liposomes for use in photodynamic therapy
[作者:Bovis, MJ; Woodhams, JH; Loizidou, M; Scheglmann, D; Bown, SG; MacRobert, AJ,期刊:Journal of controlled release, 页码:196-205 , 文章类型: Article,,卷期:2012年157-2]
- Pegylated liposomal nanocarriers have been developed with the aim of achieving improved uptake of the clinical PDT photosensitiser, m-THPC, into target tissues through increased circulation time and bioavailability. This...
- Improvement of CXCR4 tracer specificity for PET imaging
[作者:Jacobson, O; Weiss, ID; Szajek, LP; Niu, G; Ma, Y; Kiesewetter, DO; Peled, A; Eden, HS; Farber, JM; Chen, XY,期刊:Journal of controlled release, 页码:216-223 , 文章类型: Article,,卷期:2012年157-2]
- Tumors expressing the chemokine receptor CXCR4 have been reported to be more aggressive and to produce more metastatic seeding in specific organs, such as the bone marrow. However, evaluation of tumors for CXCR4 expressi...
- Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors
[作者:Sirsi, SR; Hernandez, SL; Zielinski, L; Blomback, H; Koubaa, A; Synder, M; Homma, S; Kandel, JJ; Yamashiro, DJ; Borden, MA,期刊:Journal of controlled release, 页码:224-234 , 文章类型: Article,,卷期:2012年157-2]
- Microbubble ultrasound contrast agents are being developed as image-guided gene carriers for targeted delivery in vivo. In this study, novel polyplex-microbubbles were synthesized, characterized and evaluated for systemi...
- Ultrasound-induced cavitation enhances the delivery and therapeutic efficacy of an oncolytic virus in an in vitro model
[作者:Bazan-Peregrino, M; Arvanitis, CD; Rifai, B; Seymour, LW; Coussios, CC,期刊:Journal of controlled release, 页码:235-242 , 文章类型: Article,,卷期:2012年157-2]
- We investigated whether ultrasound-induced cavitation at 0.5 MHz could improve the extravasation and distribution of a potent breast cancer-selective oncolytic adenovirus, AdEHE2F-Luc, to tumour regions that are remote f...
- Addition of ascorbic acid to the extracellular environment activates lipoplexes of a ferrocenyl lipid and promotes cell transfection
[作者:Aytar, BS; Muller, JPE; Golan, S; Hata, S; Takahashi, H; Kondo, Y; Talmon, Y; Abbott, NL; Lynn, DM,期刊:Journal of controlled release, 页码:249-259 , 文章类型: Article,,卷期:2012年157-2]
- The level of cell transfection mediated by lipoplexes formed using the ferrocenyl lipid bis(11-ferrocenylundecyl) dimethylammonium bromide (BFDMA) depends strongly on the oxidation state of the two ferrocenyl groups of t...
- Efficient skin permeation of soluble proteins via flexible and functional nano-carrier
[作者:Choi, WI; Lee, JH; Kim, JY; Kim, JC; Kim, YH; Tae, G,期刊:Journal of controlled release, 页码:272-278 , 文章类型: Article,,卷期:2012年157-2]
- In spite of several intrinsic and distinct advantages, a topical and transdermal administration of drugs has been limited mainly due to very low permeability of drugs across skin. Especially, it is generally regarded tha...
- EGFR-targeted stearoyl gemcitabine nanoparticles show enhanced anti-tumor activity
[作者:Sandoval, MA; Sloat, BR; Lansakara, DSP; Kumar, A; Rodriguez, BL; Kiguchi, K; DiGiovanni, J; Cui, ZR,期刊:Journal of controlled release, 页码:287-296 , 文章类型: Article,,卷期:2012年157-2]
- Previously, it was shown that a novel 4-(N)-stearoyl gemcitabine nanoparticle formulation was more effective than gemcitabine hydrochloride in controlling the growth of model mouse or human tumors pre-established in mice...
- Biophysical properties of chitosan/siRNA polyplexes: Profiling the polymer/siRNA interactions and bioactivity
[作者:Holzerny, P; Ajdini, B; Heusermann, W; Bruno, K; Schuleit, M; Meinel, L; Keller, M,期刊:Journal of controlled release, 页码:297-304 , 文章类型: Article,,卷期:2012年157-2]
- Chitosans are naturally occurring polymers widely used in life science to mediate intracellular uptake of nucleic acids such as siRNA. Four chitosans of fungal origin (Agaricus bisporus; molecular weights MW = 44, 63, 93...
|