- Hyperhomocysteinemia Increases beta-Amyloid by Enhancing Expression of gamma-Secretase and Phosphorylation of Amyloid Precursor Protein in Rat Brain
[作者：Zhang, CE; Wei, W; Liu, YH; Peng, JH; Tian, Q; Liu, GP; Zhang, Y; Wang, JZ,期刊：American Journal of Pathology, 页码：1481-1491 , 文章类型： Article，,卷期：2009年174-4]
- Hyperhomocysteinemia and beta-amyloid (A beta) overproduction are critical etiological and pathological factors in Alzheimer disease, respectively; however, the intrinsic link between them is still missing. Here, we foun...
- Kinase-Dependent and -Independent Roles of EphA2 in the Regulation of Prostate Cancer Invasion and Metastasis
[作者：Taddei, ML; Parri, M; Angelucci, A; Onnis, B; Bianchini, F; Giannoni, E; Raugei, G; Calorini, L; Rucci, N; Teti, A; Bologna, M; Chiarugi, P,期刊：American Journal of Pathology, 页码：1492-1503 , 文章类型： Article，,卷期：2009年174-4]
- Ligand-activated Eph tyrosine kinases regulate cellular repulsion, morphology, adhesion, and motility. EphA2 kinase is frequently up-regulated in several different types of cancers, including prostate, breast, colon, and...
- Monitoring of Urinary L-Type Fatty Acid-Binding Protein Predicts Histological Severity of Acute Kidney Injury
[作者：Negishi, K; Noiri, E; Doi, K; Maeda-Mamiya, R; Sugaya, T; Portilla, D; Fujita, T,期刊：American Journal of Pathology, 页码：1154-1159 , 文章类型： Article，,卷期：2009年174-4]
- The present study aimed to evaluate whether levels of urinary L-type fatty acid-binding protein (L-FABP) could be used to monitor histological injury in acute kidney injury (AKI) induced by cis-platinum (GP) injection an...
- RNA Interference-Mediated Inhibition of Erythropoietin Receptor Expression Suppresses Tumor Growth and Invasiveness in A2780 Human Ovarian Carcinoma Cells
[作者：Paragh, G; Kumar, SM; Rakosy, Z; Choi, SC; Xu, XW; Acs, G,期刊：American Journal of Pathology, 页码：1504-1514 , 文章类型： Article，,卷期：2009年174-4]
- Although recombinant human erythropoietin (rHuEpo) has revolutionized the treatment of anemia, recent clinical trials suggested that rHuEpo use may be associated with decreased survival in cancer patients. Although the e...
- Regulation of Prostate Cancer Progression by Galectin-3
[作者：Wang, Y; Nangia-Makker, P; Tait, L; Balan, V; Hogan, V; Pienta, KJ; Raz, A,期刊：American Journal of Pathology, 页码：1515-1523 , 文章类型： Article，,卷期：2009年174-4]
- Galectin-3, a beta-galactoside-binding protein, has been implicated in a variety of biological functions including cell proliferation, apoptosis, angiogenesis, tumor progression, and metastasis. The present study was und...
- Specific Detection of CD56 (NCAM) Isoforms for the Identification of Aggressive Malignant Neoplasms with Progressive Development
[作者：Gattenlohner, S; Stuhmer, T; Leich, E; Reinhard, M; Etschmann, B; Volker, HU; Rosenwald, A; Serfling, E; Bargou, RC; Ertl, G; Einsele, H; Muller-Hermelink, HK,期刊：American Journal of Pathology, 页码：1160-1171 , 文章类型： Article，,卷期：2009年174-4]
- Alternative splicing of transcripts from many cancer-associated genes is believed to play a major role in carcinogenesis as well as in tumor progression. Alternative splicing of one such gene, the neural cell adhesion mo...
- Alterations in Fatty Acid Utilization and an Impaired Antioxidant Defense Mechanism Are Early Events in Podocyte Injury A Proteomic Analysis
[作者：Mayrhofer, C; Krieger, S; Huttary, N; Chang, MWF; Grillari, J; Allmaier, G; Kerjaschki, D,期刊：American Journal of Pathology, 页码：1191-1202 , 文章类型： Article，,卷期：2009年174-4]
- Ultrastructural alterations of podocytes are closely associated with loss of glomerular filtration function. In the present study, we explored changes at the proteome level that paralleled the disturbances of podocyte ar...
- Gab2-Mediated Signaling Promotes Melanoma Metastasis
[作者：Horst, B; Gruvberger-Saal, SK; Hopkins, BD; Bordone, L; Yang, Y; Chernoff, KA; Uzoma, I; Schwipper, V; Liebau, J; Nowak, NJ; Brunner, G; Owens, D; Rimm, DL; Parsons, R; Celebi, JT,期刊：American Journal of Pathology, 页码：1524-1533 , 文章类型： Article，,卷期：2009年174-4]
- Metastatic melanoma is a disease with a poor prognosis that currently lacks effective treatments. Critical biological features of metastasis include acquisition of migratory competence, growth factor independence, and in...
- Urinary L-Type Fatty Acid-Binding Protein Can Reflect Renal Tubulointerstitial Injury
[作者：Tanaka, T; Doi, K; Maeda-Mamiya, R; Negishi, K; Portilla, D; Sugaya, T; Fujita, T; Noiri, E,期刊：American Journal of Pathology, 页码：1203-1211 , 文章类型： Article，,卷期：2009年174-4]
- This study aimed to elucidate the role of L-type fatty acid-binding protein (L-FABP) in renal tubulointerstitial injury using a mouse adenine-induced renal injury model. C57BL/6 mice fed excess dietary adenine for 6 week...
- GLUT1 Expression Is Increased in Hepatocellular Carcinoma and Promotes Tumorigenesis
[作者：Amann, T; Maegdefrau, U; Hartmann, A; Agaimy, A; Marienhagen, J; Weiss, TS; Stoeltzing, O; Warnecke, C; Scholmerich, J; Oefner, PJ; Kreutz, M; Bosserhoff, AK; Hellerbrand, C,期刊：American Journal of Pathology, 页码：1544-1552 , 文章类型： Article，,卷期：2009年174-4]
- Accelerated glycolysis is one of the biochemical characteristics of cancer cells. The glucose transporter isoform 1 (GLUT1) gene encodes a key rate-limiting factor in glucose transport into cancer cells. However, its exp...
- Experimental Autoimmune Vasculitis An Animal Model of Anti-neutrophil Cytoplasmic Autoantibody-Associated Systemic Vasculitis
[作者：Little, MA; Smyth, L; Salama, AD; Mukherjee, S; Smith, J; Haskard, D; Nourshargh, S; Cook, HT; Pusey, CD,期刊：American Journal of Pathology, 页码：1212-1220 , 文章类型： Article，,卷期：2009年174-4]
- The morbidity burden associated with anti-neutrophil cytoplasmic autoantibody-associated vasculitis is increasing, and many novel biological therapies are now entering the drug development pipeline. There is thus an urge...
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