- Practical and Scalable Synthesis of a Selective CCK1 Receptor Antagonist
[作者:MAPES CHRISTOPHER M; MANI NEELAKANDHA S; DENG XIAOHU; PANDIT CHENNAGIRI R; MCCLURE KELLY J; PIPPEL MARNA C W; SEHON CLARK A; GOMEZ LAURENT; SHINDE SHIRIN; BREITENBUCHER J GUY; JONES TODD K,期刊:Journal of Organic Chemistry, 页码:7950-7953 , 文章类型: Article,,卷期:2010年75-22]
- We describe a practical and scalable route to compound (Z)-1, a selective CCK1 receptor antagonist Notable features of this concise route are (1) a regioselective construction of the pyrazole core through the reaction of...
- A Concise Access to 3-Substituted 2-Pyrones
[作者:FREBAULT FREDERIC; OLIVEIRA MARIA TERESA; WOSTEFELD ECKHARD; MAULIDE NUNO,期刊:Journal of Organic Chemistry, 页码:7962-7965 , 文章类型: Article,,卷期:2010年75-22]
- The development of a modular synthesis of 3-substituted-2-pyrones is described The attainment of this strategy hinges on a new electrophilic pyrone derivative which can be readily prepared on a multigram scale and which ...
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