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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共27条记录   Insulin redirects differentiation from cardiogenic mesoderm and endoderm to neuroectoderm in differentiating human embryonic stem cells [作者：Freund, C; Oostwaard, DWV; Monshouwer-Kloots, J; van den Brink, S; van Rooijen, M; Xu, XQ; Zweigerdt, R; Mummery, C; Passier, R,期刊：Stem Cells, 页码：724-733 , 文章类型： Article，,卷期：2008年26-3] Human embryonic stem cells (hESC) can proliferate indefinitely while retaining the capacity to form derivatives of all three germ layers. We have reported previously that hESC differentiate into cardiomyocytes when cocul... Tex19, a mammalian-specific protein with a restricted expression in pluripotent stem cells and germ line [作者：Kuntz, S; Kieffer, E; Bianchetti, L; Lamoureux, N; Fuhrmann, G; Viville, S,期刊：Stem Cells, 页码：734-744 , 文章类型： Article，,卷期：2008年26-3] Although the properties of embryonic stem (ES) cells make these cells very attractive in the field of replacement therapy, the molecular mechanisms involved in the maintenance of their pluripotency are not fully characte... High-glucose-induced prostaglandin E-2 and peroxisome proliferator-activated receptor delta promote mouse embryonic stem cell proliferation [作者：Kim, YH; Han, HJ,期刊：Stem Cells, 页码：745-755 , 文章类型： Article，,卷期：2008年26-3] Peroxisome proliferator-activated receptor is a nuclear receptor that has been implicated in blastocyst implantation, cell cycle, and pathogenesis of diabetes. However, the signal cascades underlying this effect are larg... Heterozygous embryonic stem cell lines derived from nonhuman primate parthenotes [作者：Dighe, V; Clepper, L; Pedersen, D; Byrne, J; Ferguson, B; Gokhale, S; Penedo, MCT; Wolf, D; Mitalipov, S,期刊：Stem Cells, 页码：756-766 , 文章类型： Article，,卷期：2008年26-3] Monoparental parthenotes represent a potential source of histocompatible stem cells that should be isogenic with the oocyte donor and therefore suitable for use in cell or tissue replacement therapy. We generated five rh... Fibroblast growth factor 4 and its novel splice isoform have opposing effects on the maintenance of human embryonic stem cell self-renewal [作者：Mayshar, Y; Rom, E; Chumakov, I; Kronman, A; Yayon, A; Benvenisty, N,期刊：Stem Cells, 页码：767-774 , 文章类型： Article，,卷期：2008年26-3] Human embryonic stem cells (HESCs) are unique in their capacity to self-renew while remaining pluripotent. This undifferentiated state must be actively maintained by secreted factors. To identify autocrine factors that m... Mitochondrial DNA transmission and transcription after somatic cell fusion to one or more cytoplasts [作者：Bowles, EJ; Tecirlioglu, RT; French, AJ; Holland, MK; John, JCS,期刊：Stem Cells, 页码：775-782 , 文章类型： Article，,卷期：2008年26-3] Following fertilization, mitochondrial DNA is inherited from the oocyte and transmitted homoplasmically. However, following nuclear transfer, mitochondrial DNA can be transmitted from both the donor cell and recipient oo... Characterization of adult prostatic progenitor/stem cells exhibiting self-renewal and multilineage differentiation [作者：Barclay, WW; Axanova, LS; Chen, W; Romero, L; Maund, SL; Soker, S; Lees, CJ; Cramer, SD,期刊：Stem Cells, 页码：600-610 , 文章类型： Article，,卷期：2008年26-3] Demonstration of the hallmarks of stem cells, self-renewal and multilineage differentiation, is a challenge that has not been met for numerous tissues postulated to possess adult stem cells, including prostate tissue. Us... Widespread nonhematopoietic tissue distribution by transplanted human progenitor cells with high aldehyde dehydrogenase activity [作者：Hess, DA; Craft, TP; Wirthlin, L; Hohm, S; Zhou, P; Eades, WC; Creer, MH; Sands, MS; Nolta, JA,期刊：Stem Cells, 页码：611-620 , 文章类型： Article，,卷期：2008年26-3] Transplanted adult progenitor cells distribute to peripheral organs and can promote endogenous cellular repair in damaged tissues. However, development of cell-based regenerative therapies has been hindered by the lack o... Distinct effects of the soluble versus membrane-bound forms of the notch ligand delta-4 on human CD34(+)CD38(low) cell expansion and differentiation [作者：Lahmar, M; Catelain, C; Poirault, S; Dorsch, M; Villeval, JL; Vainchenker, W; Albagli, O; Lauret, E,期刊：Stem Cells, 页码：621-629 , 文章类型： Article，,卷期：2008年26-3] Although Notch ligands are considered to activate signaling through direct cell-cell contact, the existence of soluble forms has been demonstrated. However, their roles remain controversial: soluble forms have been repor... Identification of a novel putative gastrointestinal stem cell and adenoma stem cell marker, doublecortin and CaM kinase-like-1, following radiation injury and in adenomatous polyposis coli/multiple intestinal neoplasia mice [作者：May, R; Riehl, TE; Hunt, C; Sureban, SM; Anant, S; Houchen, CW,期刊：Stem Cells, 页码：630-637 , 文章类型： Article，,卷期：2008年26-3] In the gut, tumorigenesis arises from intestinal or colonic crypt stem cells. Currently, no definitive markers exist that reliably identify gut stem cells. Here, we used the putative stem cell marker doublecortin and CaM... Human dental pulp stem cells improve left ventricular function, induce angiogenesis, and reduce infarct size in rats with acute myocardial infarction [作者：Gandia, C; Arminan, A; Garcia-Verdugo, JM; Lledo, E; Ruiz, A; Minana, MD; Sanchez-Torrijos, J; Paya, R; Mirabet, V; Carbonell-Uberos, F; Llop, M; Montero, JA; Sepulveda, P,期刊：Stem Cells, 页码：638-645 , 文章类型： Article，,卷期：2008年26-3] Human dental pulp contains precursor cells termed dental pulp stem cells (DPSC) that show self-renewal and multilineage differentiation and also secrete multiple proangiogenic and antiapoptotic factors. To examine whethe... Repopulating activity of ex vivo-expanded murine hematopoietic stem cells resides in the CD48(-)c-Kit(+)Sca-1(+)lineage marker(-) cell population [作者：Noda, S; Horiguchi, K; Ichikawa, H; Miyoshia, H,期刊：Stem Cells, 页码：646-655 , 文章类型： Article，,卷期：2008年26-3] A better understanding of the biology of cultured hematopoietic stem cells (HSCs) is required to achieve ex vivo expansion of HSCs. In this study, clonal analysis of the surface phenotype and repopulating activity of ex ... Unique dielectric properties distinguish stem cells and their differentiated progeny [作者：Flanagan, LA; Lu, J; Wang, L; Marchenko, SA; Jeon, NL; Lee, AP; Monuki, ES,期刊：Stem Cells, 页码：656-665 , 文章类型： Article，,卷期：2008年26-3] The relatively new field of stem cell biology is hampered by a lack of sufficient means to accurately determine the phenotype of cells. Cell-type-specific markers, such as cell surface proteins used for flow cytometry or... Notch signaling through jagged-1 is necessary to initiate chondrogenesis in human bone marrow stromal cells but must be switched off to complete chondrogenesis [作者：Oldershaw, RA; Tew, SR; Russell, AM; Meade, K; Hawkins, R; McKay, TR; Brennan, KR; Hardingham, TE,期刊：Stem Cells, 页码：666-674 , 文章类型： Article，,卷期：2008年26-3] We investigated Notch signaling during chondrogenesis in human bone marrow stromal cells (hMSC) in three-dimensional cell aggregate culture. Expression analysis of Notch pathway genes in 14-day chondrogenic cultures show... Bone marrow-derived cells exhibiting lung epithelial cell characteristics are enriched in vivo using methylguanine DNA methyltransferase-mediated drug resistance [作者：Reese, JS; Roth, JC; Gerson, SL,期刊：Stem Cells, 页码：675-681 , 文章类型： Article，,卷期：2008年26-3] Previous studies have suggested that donor bone marrow-derived cells can differentiate into lung epithelial cells at low frequency. We investigated whether we could enrich the number of donor-derived hematopoietic cells ... Functional structure of adipocytes differentiated from human umbilical cord stroma-derived stem cells [作者：Karahuseyinoglu, S; Kocaefe, C; Balci, D; Erdemli, E; Can, A,期刊：Stem Cells, 页码：682-691 , 文章类型： Article，,卷期：2008年26-3] It has been previously demonstrated that human umbilical cord stroma-derived stem cells (HUCSCs) are competent to differentiate into adipocytes. However, controversies have arisen as to whether HUCSCs can become mature a...