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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共30条记录   Hedgehog serves as a mitogen and survival factor during embryonic stem cell neurogenesis [作者：Cai, C; Thorne, J; Grabel, L,期刊：Stem Cells, 页码：1097-1108 , 文章类型： Article，,卷期：2008年26-5] Hedgehog (Hh) signaling is involved in a wide range of important biological activities. Within the vertebrate central nervous system, Sonic Hedgehog (Shh) can act as a morphogen or mitogen that regulates the patterning, ... Epigenetic marking prepares human HOXA cluster for the activation during differentiation of pluripotent cells [作者：Atkinson, SP; Koch, CM; Clelland, GK; Willcox, S; Fowler, JC; Stewart, R; Lako, M; Dunham, I; Armstrong, L,期刊：Stem Cells, 页码：1174-1185 , 文章类型： Article，,卷期：2008年26-5] Activation of Hox gene clusters is an early event in embryonic development since individual members play important roles in patterning of the body axis. Their functions require precise control of spatiotemporal expressio... Functional network reconstruction reveals somatic stemness genetic maps and dedifferentiation-like transcriptome reprogramming induced by GATA2 [作者：Huang, TS; Hsieh, JY; Wu, YH; Jen, CH; Tsuang, YH; Chiou, SH; Partanen, J; Anderson, H; Jaatinen, T; Yu, YH; Wang, HW,期刊：Stem Cells, 页码：1186-1201 , 文章类型： Article，,卷期：2008年26-5] Somatic stem cell transplantation holds great promise in regenerative medicine. The best-characterized adult stem cells are mesenchymal stem cells (MSCs), neural stem cells (NSCs), and CD133(+) hematopoietic stem cells (... Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells [作者：Li, N; Singh, S; Cherukuri, P; Li, H; Yuan, ZQ; Ellisen, LW; Wang, BL; Robbins, D; Direnzo, J,期刊：Stem Cells, 页码：1253-1264 , 文章类型： Article，,卷期：2008年26-5] TP63 is required for preservation of epithelial regenerative stasis and regulates the activity of diverse genetic pathways; however, specific effector pathways are poorly understood. Data presented here indicate that rec... Hes1 regulates corneal development and the function of corneal epithelial stem/progenitor cells [作者：Nakamura, T; Ohtsuka, T; Sekiyama, E; Cooper, LJ; Kokubu, H; Fullwood, NJ; Barrandon, Y; Kageyama, R; Kinoshita, S,期刊：Stem Cells, 页码：1265-1274 , 文章类型： Article，,卷期：2008年26-5] Hes1, a major target gene in Notch signaling, regulates the fate and differentiation of various cell types in many developmental systems. To gain a novel insight into the role of Hes1 in corneal tissue, we performed gain... Evolution of the c-kit-positive cell response to pathological challenge in the myocardium [作者：Fransioli, J; Bailey, B; Gude, NA; Cottage, CT; Muraski, JA; Emmanuel, G; Wu, W; Alvarez, R; Rubio, M; Ottolenghi, S; Schaefer, E; Sussman, MA,期刊：Stem Cells, 页码：1315-1324 , 文章类型： Article，,卷期：2008年26-5] Cumulative evidence indicates that myocardium responds to growth or injury by recruitment of stem and/or progenitor cells that participate in repair and regenerative processes. Unequivocal identification of this populati... Alkaline phosphatase-positive colony formation is a sensitive, specific, and quantitative indicator of undifferentiated human embryonic stem cells [作者：O'Connor, MD; Kardel, MD; Iosfina, I; Youssef, D; Lu, M; Li, MM; Vercauteren, S; Nagy, A; Eaves, CJ,期刊：Stem Cells, 页码：1109-1116 , 文章类型： Article，,卷期：2008年26-5] Human embryonic stem cells (hESCs) can be maintained in vitro as immortal pluripotent cells but remain responsive to many differentiation-inducing signals. Investigation of the initial critical events involved in differe... Activation of Wnt signaling in hematopoietic regeneration [作者：Congdon, KL; Voermans, C; Ferguson, EC; Dimascio, LN; Uqoezwa, M; Zhao, C; Reya, T,期刊：Stem Cells, 页码：1202-1210 , 文章类型： Article，,卷期：2008年26-5] Hematopoietic stem cells (HSCs) respond to injury by rapidly proliferating and regenerating the hematopoietic system. Little is known about the intracellular programs that are activated within HSCs during this regenerati... Carboxypeptidase M expressed by human bone marrow cells cleaves the C-terminal lysine of stromal cell-derived factor-1 alpha: Another player in hematopoietic stem/progenitor cell mobilization? [作者：Marquez-Curtis, L; Jalili, A; Deiteren, K; Shirvaikar, N; Lambeir, AM; Janowska-Wieczorek, A,期刊：Stem Cells, 页码：1211-1220 , 文章类型： Article，,卷期：2008年26-5] Carboxypeptidase M (CPM) is a membrane-bound zinc-dependent protease that cleaves C-terminal basic residues, such as arginine or lysine, from peptides/proteins. We examined whether CPM is expressed by hematopoietic and s... Immunogenicity of human mesenchymal stem cells in HLA-class I-restricted T-Cell responses against viral or tumor-associated antigens [作者：Morandi, F; Raffaghello, L; Bianchi, G; Meloni, F; Salis, A; Millo, E; Ferrone, S; Barnaba, V; Pistoia, V,期刊：Stem Cells, 页码：1275-1287 , 文章类型： Article，,卷期：2008年26-5] Human mesenchymal stem cells (MSC) are immunosuppressive and poorly immunogenic but may act as antigen-presenting cells (APC) for CD4(+) T-cell responses; here we have investigated their ability to serve as APC for in vi... Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment [作者：Mylotte, LA; Duffy, AM; Murphy, M; O'Brien, T; Samali, A; Barry, F; Szegezdi, E,期刊：Stem Cells, 页码：1325-1336 , 文章类型： Article，,卷期：2008年26-5] The application of mesenchyrnal stem cells (MSCs) for myocardial repair following ischemic injury is of strong interest, but current knowledge regarding the survival and retention of differentiation potency of stem cells... Conditional stabilization of beta-catenin expands the pool of lung stem cells [作者：Reynolds, SD; Zemke, AC; Giangreco, A; Brockway, BL; Teisanu, RM; Drake, JA; Mariani, T; Di, PYP; Taketo, MM; Stripp, BR,期刊：Stem Cells, 页码：1337-1346 , 文章类型： Article，,卷期：2008年26-5] Maintenance of classic stem cell hierarchies is dependent upon stem cell self-renewal mediated in part by Wnt/beta-catenin regulation of the cell cycle. This function is critical in rapidly renewing tissues due to the ob... Efficient differentiation of functional hepatocytes from human embryonic stem cells [作者：Agarwal, S; Holton, KL; Lanza, R,期刊：Stem Cells, 页码：1117-1127 , 文章类型： Article，,卷期：2008年26-5] Differentiation of human embryonic stem cells (hESCs) to specific functional cell types can be achieved using methods that mimic in vivo embryonic developmental programs. Current protocols for generating hepatocytes from... A comparison of protocols used to generate insulin-producing cell clusters from mouse embryonic stem cells [作者：Boyd, AS; Wu, DC; Higashi, Y; Wood, KJ,期刊：Stem Cells, 页码：1128-1137 , 文章类型： Article，,卷期：2008年26-5] Embryonic stem cells (ESCs) have the capacity to generate a panoply of tissue types and may therefore provide an alternative source of tissue in regenerative medicine to treat potentially debilitating conditions like Typ... Induction of neurogenesis in nonconventional neurogenic regions of the adult central nervous system by niche astrocyte-produced signals [作者：Jiao, J; Chen, DF,期刊：Stem Cells, 页码：1221-1230 , 文章类型： Article，,卷期：2008年26-5] The central nervous system (CNS) of adult mammals regenerates poorly; in vivo, neurogenesis occurs only in two restricted areas, the hippocampal subgranular zone (SGZ) and the subventricular zone (SVZ). Neurogenic potent... Mobilization of hematopoietic progenitor cells by yeast-derived beta-glucan requires activation of matrix metalloproteinase-9 [作者：Cramer, DE; Wagner, S; Li, B; Liu, J; Hansen, R; Reca, R; Wu, W; Surma, EZ; Laber, DA; Ratajczak, MZ; Yan, J,期刊：Stem Cells, 页码：1231-1240 , 文章类型： Article，,卷期：2008年26-5] Poly-(1,6)-beta-D-glucopyranosyl-(1,3)-beta-D-glucopyranose (PGG) beta-glucan is a soluble yeast-derived polysaccharide that has previously been shown to induce hematopoietic progenitor cell (HPC) mobilization. However, ...