- Local delivery of granulocyte colony stimulating factor-mobilized CD34-positive progenitor cells using bioscaffold for modality of unhealing bone fracture
[作者:Mifune, Y; Matsumoto, T; Kawamoto, A; Kuroda, R; Shoji, T; Iwasaki, H; Kwon, SM; Miwa, M; Kurosaka, M; Asahara, T,期刊:Stem Cells, 页码:1395-1405 , 文章类型: Article,,卷期:2008年26-6]
- We recently reported that i.v. transplantation of adult human circulating CD34+ cells, an endothelial/hematopoietic progenitor-enriched cell population, contributes to fracture healing through the enhancement of vasculog...
- Comprehensive MicroRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence
[作者:Laurent, LC; Chen, J; Ulitsky, I; Mueller, FJ; Lu, C; Shamir, R; Fan, JB; Loring, JF,期刊:Stem Cells, 页码:1506-1516 , 文章类型: Article,,卷期:2008年26-6]
- Embryonic stem cells are unique among cultured cells in their ability to self-renew and differentiate into a wide diversity of cell types, suggesting that a specific molecular control network underlies these features. Hu...
- Sohlh2 knockout mice are male-sterile because of degeneration of differentiating type A spermatogonia
[作者:Hao, J; Yamamoto, M; Richardson, TE; Chapman, KM; Denard, BS; Hammer, RE; Zhao, GQ; Hamra, FK,期刊:Stem Cells, 页码:1587-1597 , 文章类型: Article,,卷期:2008年26-6]
- The spermatogenesis and oogenesis-specific transcription factor Sohlh2 is normally expressed only in premeiotic germ cells. In this study, Sohlh2 and several other germ cell transcripts were found to be induced in mouse ...
- Urokinase plasminogen activator and urokinase plasminogen activator receptor mediate human stem cell tropism to malignant solid tumors
[作者:Gutova, M; Najbauer, J; Frank, RT; Kendall, SE; Gevorgyan, A; Metz, MZ; Guevorkian, M; Edmiston, M; Zhao, D; Glackin, CA; Kim, SU; Aboody, KS,期刊:Stem Cells, 页码:1406-1413 , 文章类型: Article,,卷期:2008年26-6]
- Human neural and mesenchymal stem cells have been identified for cell-based therapies in regenerative medicine and as vehicles for delivering therapeutic agents to areas of injury and tumors. However, the signals require...
- Direct orthotopic transplantation of fresh surgical specimen preserves CD133(+) tumor cells in clinically relevant mouse models of medulloblastoma and glioma
[作者:Shu, Q; Wong, KK; Su, JM; Adesina, AM; Yu, LT; Tsang, YTM; Antalffy, BC; Baxter, P; Perlaky, L; Yang, JH; Dauser, RC; Chintagumpala, M; Blaney, SM; Lau, CC; Li, XN,期刊:Stem Cells, 页码:1414-1424 , 文章类型: Article,,卷期:2008年26-6]
- Recent identification of cancer stem cells in medulloblastoma (MB) and high-grade glioma has stimulated an urgent need for animal models that will not only replicate the biology of these tumors, but also preserve their c...
- Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease
[作者:Hedlund, E; Pruszak, J; Lardaro, T; Ludwig, W; Vinuela, A; Kim, KS; Isacson, O,期刊:Stem Cells, 页码:1526-1536 , 文章类型: Article,,卷期:2008年26-6]
- Both fetal ventral mesencephalic (VM) and embryonic stem (ES) cell-derived dopamine neurons have been used successfully to correct behavioral responses in animal models of Parkinson's disease. However, grafts derived fro...
- Autocrine fibroblast growth factor 2 increases the multipotentiality of human adipose-derived mesenchymal stem cells
[作者:Rider, DA; Dombrowski, C; Sawyer, AA; Ng, GHB; Leong, D; Hutmacher, DW; Nurcombe, V; Cool, SM,期刊:Stem Cells, 页码:1598-1608 , 文章类型: Article,,卷期:2008年26-6]
- Multipotent mesenchymal stem cells (MSCs), first identified in the bone marrow, have subsequently been found in many other tissues, including fat, cartilage, muscle, and bone. Adipose tissue has been identified as an alt...
- A putative role for RHAMM/HMMR as a negative marker of stem cell-containing population of human limbal epithelial cells
[作者:Ahmad, S; Kolli, S; Li, DQ; de Paiva, CS; Pryzborski, S; Dimmick, I; Armstrong, L; Figueiredo, FC; Lako, M,期刊:Stem Cells, 页码:1609-1619 , 文章类型: Article,,卷期:2008年26-6]
- The corneal epithelium is maintained by stem cells located at the periphery of the cornea in a region known as the limbus. Depletion of limbal stem cells (LSCs) results in limbal stem cell deficiency. Treatments for this...
- Sustained long-term engraftment and transgene expression of peripheral blood CD34(+) cells transduced with third-generation lentiviral vectors
[作者:Tesio, M; Gammaitoni, L; Gunetti, M; Leuci, V; Pignochino, Y; Jordaney, N; Capellero, S; Cammarata, C; Caione, L; Migliaretti, G; Fagioli, F; Tabilio, A; Aglietta, M; Piacibello, W,期刊:Stem Cells, 页码:1620-1627 , 文章类型: Article,,卷期:2008年26-6]
- As mobilized peripheral blood (MPB) represents an attractive cell source for gene therapy, we investigated the ability of third-generation lentiviral vectors (LVs) to transfer the enhanced green fluorescent protein gene ...
- Platelet-derived growth factor-D overexpression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells
[作者:Kong, DJ; Wang, ZW; Sarkar, SH; Li, YW; Banerjee, S; Saliganan, A; Kim, HRC; Cher, ML; Sarkar, FH,期刊:Stem Cells, 页码:1425-1435 , 文章类型: Article,,卷期:2008年26-6]
- The majority of human malignancies are believed to have epithelial origin, and the progression of cancer is often associated with a transient process named epithelial-mesenchymal transition (EMT). EMT is characterized by...
- Nucleofection mediates high-efficiency stable gene knockdown and transgene expression in human embryonic stem cells
[作者:Hohenstein, KA; Pyle, AD; Chern, JY; Lock, LF; Donovan, PJ,期刊:Stem Cells, 页码:1436-1443 , 文章类型: Article,,卷期:2008年26-6]
- High-efficiency genetic modification of human embryonic stem (hES) cells would enable manipulation of gene activity, routine gene targeting, and development of new human disease models and treatments. Chemical transfecti...
- Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages
[作者:Schenke-Layland, K; Rhodes, KE; Angelis, E; Butylkova, Y; Heydarkhan-Hagvall, S; Gekas, C; Zhang, R; Goldhaber, JI; Mikkola, HK; Plath, K; Maclellan, WR,期刊:Stem Cells, 页码:1537-1546 , 文章类型: Article,,卷期:2008年26-6]
- Forced expression of the four transcription factors Oct4, Sox2, c-Myc, and Klf4 is sufficient to confer a pluripotent state upon the murine fibroblast genome, generating induced pluripotent stem (iPS) cells. Although the...
- Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells
[作者:Huynh, HD; Iizuka, S; Kaba, M; Kirak, O; Zheng, J; Lodish, HF; Zhang, CC,期刊:Stem Cells, 页码:1628-1635 , 文章类型: Article,,卷期:2008年26-6]
- Successful hematopoietic stem cell (HSC) transplantation is often limited by the numbers of HSCs, and robust methods to expand HSCs ex vivo are needed. We previously showed that angiopoietin-like proteins (Angptls), a gr...
- Neuropeptide Y promotes neurogenesis in murine subventricular zone
[作者:Agasse, F; Bernardino, L; Kristiansen, H; Christiansen, SH; Ferreira, R; Silva, B; Grade, S; Woldbye, DPD; Malva, JO,期刊:Stem Cells, 页码:1636-1645 , 文章类型: Article,,卷期:2008年26-6]
- Stem cells of the subventricular zone (SVZ) represent a reliable source of neurons for cell replacement. Neuropeptide Y (NPY) promotes neurogenesis in the hippocampal subgranular layer and the olfactory epithelium and ma...
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