- Intra-bone marrow injection of donor bone marrow cells suspended in collagen gel retains injected cells in bone marrow, resulting in rapid hemopoietic recovery in mice
[作者:Shi, M; Adachi, Y; Shigematsu, A; Koike-Kiriyama, N; Feng, W; Yanai, S; Yunze, C; Lian, ZX; Li, J; Ikehara, S,期刊:Stem Cells, 页码:2211-2216 , 文章类型: Article,,卷期:2008年26-9]
- We have recently developed an innovative bone marrow transplantation (BMT) method, intra-bone marrow (IBM)-BMT, in which donor bone marrow cells (BMCs) are injected directly into the recipient bone marrow (BM), resulting...
- Chemoattractive activity of Sonic Hedgehog in the adult subventricular zone modulates the number of neural precursors reaching the olfactory bulb
[作者:Angot, E; Loulier, K; Nguyen-Ba-Charvet, KT; Gadeau, AP; Ruat, M; Traiffort, E,期刊:Stem Cells, 页码:2311-2320 , 文章类型: Article,,卷期:2008年26-9]
- The adult subventricular zone (SVZ) supports neural stem cell self-renewal and differentiation and continually gives rise to new neurons throughout adult life. The mechanisms orienting the migration of neuroblasts from t...
- Oxytocin controls differentiation of human mesenchymal stem cells and reverses osteoporosis
[作者:Elabd, C; Basillais, A; Beaupied, H; Breuil, V; Wagner, N; Scheideler, M; Zaragosi, LE; Massiera, F; Lemichez, E; Trajanoski, Z; Carle, G; Euller-Ziegler, L; Ailhaud, G; Benhamou, CL; Dani, C; Amri, EZ,期刊:Stem Cells, 页码:2399-2407 , 文章类型: Article,,卷期:2008年26-9]
- Osteoporosis constitutes a major worldwide public health burden characterized by enhanced skeletal fragility. Bone metabolism is the combination of bone resorption by osteoclasts and bone formation by osteoblasts. Wherea...
- Concise review: Mesenchymal stromal cells: Potential for cardiovascular repair
[作者:Psaltis, PJ; Zannettino, ACW; Worthley, SG; Gronthos, S,期刊:Stem Cells, 页码:2201-2210 , 文章类型: Review,,卷期:2008年26-9]
- Cellular therapy for cardiovascular disease heralds an exciting frontier of research. Mesenchymal stromal cells (MSCs) are present in adult tissues, including bone marrow and adipose, from which they can be easily isolat...
- Neural induction with Neurogenin1 increases the therapeutic effects of mesenchymal stem cells in the ischemic brain
[作者:Kim, SS; Yoo, SW; Park, TS; Ahn, SC; Jeong, HS; Kim, JW; Chang, DY; Cho, KG; Kim, SU; Huh, Y; Lee, JE; Lee, SY; Lee, YD; Suh-Kim, H,期刊:Stem Cells, 页码:2217-2228 , 文章类型: Article,,卷期:2008年26-9]
- Mesenchymal stem cells (MSCs) have been shown to ameliorate a variety of neurological dysfunctions. This effect is believed to be mediated by their paracrine functions, since these cells rarely differentiate into neurona...
- Therapeutic potential of mesenchymal stem cells producing interferon-alpha in a mouse melanoma lung metastasis model
[作者:Ren, CC; Kumar, S; Chanda, D; Chen, J; Mountz, JD; Ponnazhagan, S,期刊:Stem Cells, 页码:2332-2338 , 文章类型: Article,,卷期:2008年26-9]
- Adult stem cells represent a potential source for cell-based therapy of cancer. The present study evaluated the potential of bone marrow-derived mesenchymal stem cells (MSC), genetically modified to express interferon (I...
- TIS21(/BTG2) negatively regulates estradiol-stimulated expansion of hematopoietic stem cells by derepressing Akt phosphorylation and inhibiting mTOR signal transduction
[作者:Kim, BC; Ryu, MS; Oh, SP; Lim, IK,期刊:Stem Cells, 页码:2339-2348 , 文章类型: Article,,卷期:2008年26-9]
It has been known that 12-O-tetradecanoyl phorbol-13-acetate-inducible sequence 21 (TIS21), ortholog of human B-cell translocation gene 2, regulates expansions of stage- specific thymocytes and hematopoietic progenito...
- A novel stem cell source for vasculogenesis in ischemia: Subfraction of side population cells from dental pulp
[作者:Iohara, K; Zheng, L; Wake, H; Ito, M; Nabekura, J; Wakita, H; Nakamura, H; Into, T; Matsushita, K; Nakashima, M,期刊:Stem Cells, 页码:2408-2418 , 文章类型: Article,,卷期:2008年26-9]
- Cell therapy with stem cells and endothelial progenitor cells (EPCs) to stimulate vasculogenesis as a potential treatment for ischemic disease is an exciting area of research in regenerative medicine. EPCs are present in...
- In vivo osteoprogenitor potency of human stromal cells from different tissues does not correlate with expression of POU5F1 or its pseudogenes
[作者:Kaltz, N; Funari, A; Hippauf, S; Delorme, B; Noel, D; Riminucci, M; Jacobs, VR; Haupl, T; Jorgensen, C; Charbord, P; Peschel, C; Bianco, P; Oostendorp, RAJ,期刊:Stem Cells, 页码:2419-2424 , 文章类型: Article,,卷期:2008年26-9]
- Expression of "stemness" markers is widely used as a predictor of stem cell properties of mesenchymal stem cells (MSC). Here, we show that bone marrow-derived (BM)-MSC show stem cell-like behavior in vivo; that is, they ...
- Scalable selection of hepatocyte- and hepatocyte precursor-like cells from culture of differentiating transgenically modified murine embryonic stem cells
[作者:Drobinskaya, I; Linn, T; Saric, T; Bretzel, RG; Bohlen, H; Hescheler, J; Kolossov, E,期刊:Stem Cells, 页码:2245-2256 , 文章类型: Review,,卷期:2008年26-9]
- Potential therapeutic applications of embryonic stem cell (ESC)-derived hepatocytes are limited by their relatively low output in differentiating ESC cultures, as well as by the danger of contamination with tumorigenic u...
- Recombinant vitronectin is a functionally defined substrate that supports human embryonic stem cell self-renewal via alpha V beta 5 integrin
[作者:Braam, SR; Zeinstra, L; Litjens, S; Ward-van Oostwaard, D; van den Brink, S; van Laake, L; Lebrin, F; Kats, P; Hochstenbach, R; Passier, R; Sonnenberg, A; Mummery, CL,期刊:Stem Cells, 页码:2257-2265 , 文章类型: Article,,卷期:2008年26-9]
- Defined growth conditions are essential for many applications of human embryonic stem cells (hESC). Most defined media are presently used in combination with Matrigel, a partially defined extracellular matrix (ECM) extra...
- Fate mapping and lineage analyses demonstrate the production of a large number of striatal neuroblasts after transforming growth factor alpha and noggin striatal infusions into the dopamine-depleted striatum
[作者:de Chevigny, A; Cooper, O; Vinuela, A; Reske-Nielsen, C; Lagace, DC; Eisch, AJ; Isacson, O,期刊:Stem Cells, 页码:2349-2360 , 文章类型: Article,,卷期:2008年26-9]
- Infusion of transforming growth factor alpha (TGF alpha) into the adult dopamine (DA)-depleted striatum generates a local population of nestin(+)/proliferating cell nuclear antigen (PCNA)(+) newborn cells. The precise or...
- Tumor necrosis factor-alpha modulates survival, proliferation, and neuronal differentiation in neonatal subventricular zone cell cultures
[作者:Bernardino, L; Agasse, F; Silva, B; Ferreira, R; Grade, S; Malva, JO,期刊:Stem Cells, 页码:2361-2371 , 文章类型: Article,,卷期:2008年26-9]
- Tumor necrosis factor (TNF)-alpha has been reported to modulate brain injury, but remarkably, little is known about its effects on neurogenesis. We report that TNF-alpha strongly influences survival, proliferation, and n...
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