- PCM1-JAK2-fusion: a potential treatment target in myelodysplastic-myeloproliferative and other hemato-lymphoid neoplasms
[作者:Hoeller, S; Walz, C; Reiter, A; Dirnhofer, S; Tzankov, A,期刊:Expert Opinion on Therapeutic Targets, 页码:53-62 , 文章类型: Review,,卷期:2011年15-1]
- Importance of the field: Activating mutations of the JAK2 gene are of tumorigenic significance in myeloproliferative neoplasms. Translocations involving the JAK2 locus are of oncogenic importance in acute leukemias, myel...
- EGFR-PI3K-AKT-mTOR signaling in head and neck squamous cell carcinomas: attractive targets for molecular-oriented therapy
[作者:Freudlsperger, C; Burnett, JR; Friedman, JA; Kannabiran, VR; Chen, Z; Van Waes, C,期刊:Expert Opinion on Therapeutic Targets, 页码:63-74 , 文章类型: Review,,卷期:2011年15-1]
- Importance of the field: Recent advances in the understanding of the oncogenesis of head and neck squamous cell carcinomas (HNSCC) have revealed multiple dysregulated signaling pathways. One frequently altered axis is th...
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