- Japanese-US Common-Arm Analysis of Paclitaxel Plus Carboplatin in Advanced Non-Small-Cell Lung Cancer: A Model for Assessing Population-Related Pharmacogenomics
[作者：Gandara, DR; Kawaguchi, T; Crowley, J; Moon, J; Furuse, K; Kawahara, M; Teramukai, S; Ohe, Y; Kubota, K; Williamson, SK; Gautschi, O; Lenz, HJ; McLeod, HL; Lara, PN; Coltman, CA; Fukuoka, M; Saijo, N; Fukushima, M; Mack, PC,期刊：Journal of clinical oncology, 页码：3540-3546 , 文章类型： Article，,卷期：2009年27-21]
- Purpose To explore whether population-related pharmacogenomics contribute to differences in patient outcomes between clinical trials performed in Japan and the United States, given similar study designs, eligibility crit...
- Quality of Life After Pelvic Radiotherapy or Vaginal Brachytherapy for Endometrial Cancer: First Results of the Randomized PORTEC-2 Trial
[作者：Nout, RA; Putter, H; Jurgenliemk-Schulz, IM; Jobsen, JJ; Lutgens, LCHW; van der Steen-Banasik, EM; Mens, JWM; Slot, A; Kroese, MCS; van Bunningen, BNFM; Smit, VTHBM; Nijman, HW; van den Tol, PP; Creutzberg, CL,期刊：Journal of clinical oncology, 页码：3547-3556 , 文章类型： Article，,卷期：2009年27-21]
- Purpose Studies on quality of life (QOL) among women with endometrial cancer have shown that patients who undergo pelvic radiotherapy report lower role functioning and more diarrhea and fatigue. In the Post Operative Rad...
- Safety, Pharmacokinetics, and Antitumor Activity of AMG 386, a Selective Angiopoietin Inhibitor, in Adult Patients With Advanced Solid Tumors
[作者：Herbst, RS; Hong, D; Chap, L; Kurzrock, R; Jackson, E; Silverman, JM; Rasmussen, E; Sun, YN; Zhong, D; Hwang, YCY; Evelhoch, JL; Oliner, JD; Le, N; Rosen, LS,期刊：Journal of clinical oncology, 页码：3557-3565 , 文章类型： Article，,卷期：2009年27-21]
- Purpose AMG 386 is an investigational peptide-Fc fusion protein (ie, peptibody) that inhibits angiogenesis by preventing the interaction of angiopoietin-1 and angiopoietin-2 with their receptor, Tie2. This first-in-human...
- Expression of ER-alpha 36, a Novel Variant of Estrogen Receptor alpha, and Resistance to Tamoxifen Treatment in Breast Cancer
[作者：Shi, L; Dong, B; Li, ZW; Lu, YW; Tao, OY; Li, JF; Wang, TF; Fan, ZQ; Fan, T; Lin, BY; Wang, ZY; Xie, YT,期刊：Journal of clinical oncology, 页码：3423-3429 , 文章类型： Article，,卷期：2009年27-21]
- Purpose Recently, a 36-kDa variant of estrogen receptor alpha (ER-alpha 66), ER-alpha 36, has been identified and cloned. ER-alpha 36 predominantly localizes on the plasma membrane and in the cytoplasm and mediates a mem...
- Topoisomerase II alpha Amplification Does Not Predict Benefit From Dose-Intense Cyclophosphamide, Doxorubicin, and Fluorouracil Therapy in HER2-Amplified Early Breast Cancer: Results of CALGB 8541/150013
[作者：Harris, LN; Broadwater, G; Abu-Khalaf, M; Cowan, D; Thor, AD; Budman, D; Cirrincione, CT; Berry, DA; Winer, EP; Hudis, CA; Hayes, DF; Friedman, P; Ellis, M; Dressler, L,期刊：Journal of clinical oncology, 页码：3430-3436 , 文章类型： Article，,卷期：2009年27-21]
- Purpose We have demonstrated that patients with HER2-amplified tumors derive more benefit from higher doses of doxorubicin-containing chemotherapy (cyclophosphamide, doxorubicin, and fluorouracil [CAF]). Because topoisom...
- Elevated Biomarkers of Inflammation Are Associated With Reduced Survival Among Breast Cancer Patients
[作者：Pierce, BL; Ballard-Barbash, R; Bernstein, L; Baumgartner, RN; Neuhouser, ML; Wener, MH; Baumgartner, KB; Gilliland, FD; Sorensen, BE; McTiernan, A; Ulrich, CM,期刊：Journal of clinical oncology, 页码：3437-3444 , 文章类型： Article，,卷期：2009年27-21]
- Purpose Chronic inflammation is believed to contribute to the development and progression of breast cancer. Systemic C-reactive protein (CRP) and serum amyloid A (SAA) are measures of low-grade chronic inflammation and p...
- Adjuvant Hormonal Therapy Use Among Insured, Low-Income Women With Breast Cancer
[作者：Kimmick, G; Anderson, R; Camacho, F; Bhosle, M; Hwang, W; Balkrishnan, R,期刊：Journal of clinical oncology, 页码：3445-3451 , 文章类型： Article，,卷期：2009年27-21]
- Purpose Use of adjuvant hormonal therapy, which significantly decreases breast cancer mortality, has not been well described among poor women, who are at higher risk of cancer-related death. Here we explore use of adjuva...
- Impact of Androgen Deprivation Therapy on Cardiovascular Disease and Diabetes
[作者：Alibhai, SMH; Duong-Hua, M; Sutradhar, R; Fleshner, NE; Warde, P; Cheung, AM; Paszat, LF,期刊：Journal of clinical oncology, 页码：3452-3458 , 文章类型： Article，,卷期：2009年27-21]
- Purpose Use of androgen deprivation therapy (ADT) may be associated with an increased risk of diabetes mellitus but the risk of both acute myocardial infarction (AMI) and cardiovascular mortality remain controversial bec...
- Gleason Score and Lethal Prostate Cancer: Does 3+4=4+3?
[作者：Stark, JR; Perner, S; Stampfer, MJ; Sinnott, JA; Finn, S; Eisenstein, AS; Ma, J; Fiorentino, M; Kurth, T; Loda, M; Giovannucci, EL; Rubin, MA; Mucci, LA,期刊：Journal of clinical oncology, 页码：3459-3464 , 文章类型： Article，,卷期：2009年27-21]
- Purpose Gleason grading is an important predictor of prostate cancer (PCa) outcomes. Studies using surrogate PCa end points suggest outcomes for Gleason score (GS) 7 cancers vary according to the predominance of pattern ...
- Conversion to Resectability Using Hepatic Artery Infusion Plus Systemic Chemotherapy for the Treatment of Unresectable Liver Metastases From Colorectal Carcinoma
[作者：Kemeny, NE; Melendez, FDH; Capanu, M; Paty, PB; Fong, Y; Schwartz, LH; Jarnagin, WR; Patel, D; D'Angelica, M,期刊：Journal of clinical oncology, 页码：3465-3471 , 文章类型： Article，,卷期：2009年27-21]
- Purpose To determine the conversion to resectability in patients with unresectable liver metastases from colorectal cancer treated with hepatic arterial infusion (HAI) plus systemic oxaliplatin and irinotecan (CPT-11).Pa...
- Dasatinib in the Treatment of Chronic Myeloid Leukemia in Accelerated Phase After Imatinib Failure: The START A Trial
[作者：Apperley, JF; Cortes, JE; Kim, DW; Roy, L; Roboz, GJ; Rosti, G; Bullorsky, EO; Abruzzese, E; Hochhaus, A; Heim, D; de Souza, CA; Larson, RA; Lipton, JH; Khoury, HJ; Kim, HJ; Sillaber, C; Hughes, TP; Erben, P; Van Tornout, J; Stone, RM,期刊：Journal of clinical oncology, 页码：3472-3479 , 文章类型： Article，,卷期：2009年27-21]
- Purpose Patients with chronic myelogenous leukemia in accelerated phase (CML-AP) that is resistant or intolerant to imatinib have limited therapeutic options. Dasatinib, a potent inhibitor of BCR-ABL and SRC-family kinas...
- Dose-Modified Oral Chemotherapy in the Treatment of AIDS-Related Non-Hodgkin's Lymphoma in East Africa
[作者：Mwanda, WO; Orem, J; Fu, PF; Banura, C; Kakembo, J; Onyango, CA; Ness, A; Reynolds, S; Johnson, JL; Subbiah, V; Bako, J; Wabinga, H; Abdallah, FK; Meyerson, HJ; Whalen, CC; Lederman, MM; Black, J; Ayers, LW; Katongole-Mbidde, E; Remick, SC,期刊：Journal of clinical oncology, 页码：3480-3488 , 文章类型： Article，,卷期：2009年27-21]
- Purpose Africa is burdened by the AIDS epidemic and attendant increase in HIV/AIDS-related malignancies. Pragmatic approaches to therapeutic intervention could be of great value. Dose-modified oral chemotherapy for AIDS-...
- Prospective Randomized Multicenter Adjuvant Dermatologic Cooperative Oncology Group Trial of Low-Dose Interferon Alfa-2b With or Without a Modified High-Dose Interferon Alfa-2b Induction Phase in Patients With Lymph Node-Negative Melanoma
[作者：Hauschild, A; Weichenthal, M; Rass, K; Linse, R; Ulrich, J; Stadler, R; Volkenandt, M; Grabbe, S; Proske, U; Schadendorf, D; Brockmeyer, N; Vogt, T; Rompel, R; Kaufmann, R; Kaatz, M; Naher, H; Mohr, P; Eigentler, T; Livingstone, E; Garbe, C,期刊：Journal of clinical oncology, 页码：3496-3502 , 文章类型： Article，,卷期：2009年27-21]
- Purpose Interferon alfa (IFN-alpha) has shown clinical efficacy in the adjuvant treatment of patients with high-risk melanoma in several clinical trials, but optimal dosing and duration of treatment are still under discu...
- Blood-Brain Barrier Disruption and Intra-Arterial Methotrexate-Based Therapy for Newly Diagnosed Primary CNS Lymphoma: A Multi-Institutional Experience
[作者：Angelov, L; Doolittle, ND; Kraemer, DF; Siegal, T; Barnett, GH; Peereboom, DM; Stevens, G; McGregor, J; Jahnke, K; Lacy, CA; Hedrick, NA; Shalom, E; Ference, S; Bell, S; Sorenson, L; Tyson, RM; Haluska, M; Neuwelt, EA,期刊：Journal of clinical oncology, 页码：3503-3509 , 文章类型： Article，,卷期：2009年27-21]
- Purpose Primary CNS lymphoma (PCNSL) is confined to the CNS and/or the eyes at presentation and is usually initially treated with intravenous methotrexate-based chemotherapy and whole-brain radiotherapy (WBRT). However, ...
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