- RNA silencing in Monterey
[作者:Rissland, OS; Lai, EC,期刊:Development, 页码:3093-3102 , 文章类型: Editorial Material,,卷期:2011年138-15]
- The tenth annual Keystone Symposium on the Mechanism and Biology of Silencing convened in Monterey, California, in March 2011. Those seeking some West Coast sunshine were, unfortunately, met with incessant precipitation ...
- Enhancer-PRE communication contributes to the expansion of gene expression domains in proliferating primordia
[作者:Perez, L; Barrio, L; Cano, D; Fiuza, UM; Muzzopappa, M; Milan, M,期刊:Development, 页码:3125-3134 , 文章类型: Article,,卷期:2011年138-15]
- Trithorax-group and Polycomb-group proteins interact with chromosomal elements, termed PRE/TREs, to ensure stable heritable maintenance of the transcriptional state of nearby genes. Regulatory elements that bind both gro...
- Snail2 controls mesodermal BMP/Wnt induction of neural crest
[作者:Shi, JL; Severson, C; Yang, JX; Wedlich, D; Klymkowsky, MW,期刊:Development, 页码:3135-3145 , 文章类型: Article,,卷期:2011年138-15]
- The neural crest is an induced tissue that is unique to vertebrates. In the clawed frog Xenopus laevis, neural crest induction depends on signals secreted from the prospective dorsolateral mesodermal zone during gastrula...
- Neuregulins are essential for spermatogonial proliferation and meiotic initiation in neonatal mouse testis
[作者:Zhang, JD; Eto, K; Honmyou, A; Nakao, K; Kiyonari, H; Abe, S,期刊:Development, 页码:3159-3168 , 文章类型: Article,,卷期:2011年138-15]
- The transition from mitosis to meiosis is unique to germ cells. In murine embryonic ovaries and juvenile testes, retinoic acid (RA) induces meiosis via the stimulated by retinoic acid gene 8 (Stra8), but its molecular pa...
- LATE MERISTEM IDENTITY2 acts together with LEAFY to activate APETALA1
[作者:Pastore, JJ; Limpuangthip, A; Yamaguchi, N; Wu, MF; Sang, Y; Han, SK; Malaspina, L; Chavdaroff, N; Yamaguchi, A; Wagner, D,期刊:Development, 页码:3189-3198 , 文章类型: Article,,卷期:2011年138-15]
- The switch from producing vegetative structures (branches and leaves) to producing reproductive structures (flowers) is a crucial developmental transition that significantly affects the reproductive success of flowering ...
- The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration
[作者:Anderson, KR; Singer, RA; Balderes, DA; Hernandez-Lagunas, L; Johnson, CW; Artinger, KB; Sussel, L,期刊:Development, 页码:3213-3224 , 文章类型: Article,,卷期:2011年138-15]
- The homeodomain transcription factor Nkx2.2 is essential for pancreatic development and islet cell type differentiation. We have identified Tm4sf4, an L6 domain tetraspanin family member, as a transcriptional target of N...
- Fgf differentially controls cross-antagonism between cardiac and haemangioblast regulators
[作者:Simoes, FC; Peterkin, T; Patient, R,期刊:Development, 页码:3235-3245 , 文章类型: Article,,卷期:2011年138-15]
- Fibroblast growth factor (Fgf) has been implicated in the control of heart size during development, although whether this is by controlling cell fate, survival or proliferation has not been clear. Here, we show that Fgf,...
- Muscle force regulates bone shaping for optimal load-bearing capacity during embryogenesis
[作者:Sharir, A; Stern, T; Rot, C; Shahar, R; Zelzer, E,期刊:Development, 页码:3247-3259 , 文章类型: Article,,卷期:2011年138-15]
- The vertebrate skeleton consists of over 200 individual bones, each with its own unique shape, size and function. We study the role of intrauterine muscle-induced mechanical loads in determining the three-dimensional mor...
- Generation of mice with functional inactivation of talpid3, a gene first identified in chicken
[作者:Bangs, F; Antonio, N; Thongnuek, P; Welten, M; Davey, MG; Briscoe, J; Tickle, C,期刊:Development, 页码:3261-3272 , 文章类型: Article,,卷期:2011年138-15]
- Specification of digit number and identity is central to digit pattern in vertebrate limbs. The classical talpid(3) chicken mutant has many unpatterned digits together with defects in other regions, depending on hedgehog...
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