- ERK signaling controls blastema cell differentiation during planarian regeneration
[作者:Tasaki, J; Shibata, N; Nishimura, O; Itomi, K; Tabata, Y; Son, FY; Suzuki, N; Araki, R; Abe, M; Agata, K; Umesono, Y,期刊:Development, 页码:2417-2427 , 文章类型: Article,,卷期:2011年138-12]
- The robust regenerative ability of planarians depends on a population of somatic stem cells called neoblasts, which are the only mitotic cells in adults and are responsible for blastema formation after amputation. The mo...
- Induced stem cell neoplasia in a cnidarian by ectopic expression of a POU domain transcription factor
[作者:Millane, RC; Kanska, J; Duffy, DJ; Seoighe, C; Cunningham, S; Plickert, G; Frank, U,期刊:Development, 页码:2429-2439 , 文章类型: Article,,卷期:2011年138-12]
- The evolutionary origin of stem cell pluripotency is an unresolved question. In mammals, pluripotency is limited to early embryos and is induced and maintained by a small number of key transcription factors, of which the...
- Sequential changes at differentiation gene promoters as they become active in a stem cell lineage
[作者:Chen, X; Lu, CG; Prado, JRM; Eun, SH; Fuller, MT,期刊:Development, 页码:2441-2450 , 文章类型: Article,,卷期:2011年138-12]
- Transcriptional silencing of terminal differentiation genes by the Polycomb group (PcG) machinery is emerging as a key feature of precursor cells in stem cell lineages. How, then, is this epigenetic silencing reversed fo...
- LEUNIG and SEUSS co-repressors regulate miR172 expression in Arabidopsis flowers
[作者:Grigorova, B; Mara, C; Hollender, C; Sijacic, P; Chen, XM; Liu, ZC,期刊:Development, 页码:2451-2456 , 文章类型: Article,,卷期:2011年138-12]
- Central to the ABCE model of flower development is the antagonistic interaction between class A and class C genes. The molecular mechanisms underlying the A-C antagonism are not completely understood. In Arabidopsis thal...
- Restoring eye size in Astyanax mexicanus blind cavefish embryos through modulation of the Shh and Fgf8 forebrain organising centres
[作者:Pottin, K; Hinaux, H; Retaux, S,期刊:Development, 页码:2467-2476 , 文章类型: Article,,卷期:2011年138-12]
- The cavefish morph of the Mexican tetra (Astyanax mexicanus) is blind at adult stage, although an eye that includes a retina and a lens develops during embryogenesis. There are, however, two major defects in cavefish eye...
- Drosophila Smt3 negatively regulates JNK signaling through sequestering Hipk in the nucleus
[作者:Huang, H; Du, GP; Chen, HQ; Liang, XH; Li, CQ; Zhu, NN; Xue, L; Ma, J; Jiao, RJ,期刊:Development, 页码:2477-2485 , 文章类型: Article,,卷期:2011年138-12]
- Post-translational modification by the small ubiquitin-related modifier (SUMO) is important for a variety of cellular and developmental processes. However, the precise mechanism(s) that connects sumoylation to specific d...
- The cell adhesion molecule DdCAD-1 regulates morphogenesis through differential spatiotemporal expression in Dictyostelium discoideum
[作者:Sriskanthadevan, S; Zhu, YY; Manoharan, K; Yang, CX; Siu, CH,期刊:Development, 页码:2487-2497 , 文章类型: Article,,卷期:2011年138-12]
- During development of Dictyostelium, multiple cell types are formed and undergo a coordinated series of morphogenetic movements guided by their adhesive properties and other cellular factors. DdCAD-1 is a unique homophil...
- Tangential migration and proliferation of intermediate progenitors of GABAergic neurons in the mouse telencephalon
[作者:Wu, SX; Esumi, S; Watanabe, K; Chen, J; Nakamura, KC; Nakamura, K; Kometani, K; Minato, N; Yanagawa, Y; Akashi, K; Sakimura, K; Kaneko, T; Tamamaki, N,期刊:Development, 页码:2499-2509 , 文章类型: Article,,卷期:2011年138-12]
- In the embryonic neocortex, neuronal precursors are generated in the ventricular zone (VZ) and accumulate in the cortical plate. Recently, the subventricular zone (SVZ) of the embryonic neocortex was recognized as an add...
- RanBPM is essential for mouse spermatogenesis and oogenesis
[作者:Puverel, S; Barrick, C; Dolci, S; Coppola, V; Tessarollo, L,期刊:Development, 页码:2511-2521 , 文章类型: Article,,卷期:2011年138-12]
- RanBPM is a recently identified scaffold protein that links and modulates interactions between cell surface receptors and their intracellular signaling pathways. RanBPM has been shown to interact with a variety of functi...
- Drosophila Mon2 couples Oskar-induced endocytosis with actin remodeling for cortical anchorage of the germ plasm
[作者:Tanaka, T; Kato, Y; Matsuda, K; Hanyu-Nakamura, K; Nakamura, A,期刊:Development, 页码:2523-2532 , 文章类型: Article,,卷期:2011年138-12]
- Drosophila pole (germ) plasm contains germline and abdominal determinants. Its assembly begins with the localization and translation of oskar (osk) RNA at the oocyte posterior, to which the pole plasm must be restricted ...
- Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27(KIP1) expression and suppressing NOTCH signaling
[作者:Hammerle, B; Ulin, E; Guimera, J; Becker, W; Guillemot, F; Tejedor, FJ,期刊:Development, 页码:2543-2554 , 文章类型: Article,,卷期:2011年138-12]
- The decision of a neural precursor to stop dividing and begin its terminal differentiation at the correct place, and at the right time, is a crucial step in the generation of cell diversity in the nervous system. Here, w...
- The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10
[作者:Agarwal, P; Verzi, MP; Nguyen, T; Hu, JX; Ehlers, ML; McCulley, DJ; Xu, SM; Dodou, E; Anderson, JP; Wei, ML; Black, BL,期刊:Development, 页码:2555-2565 , 文章类型: Article,,卷期:2011年138-12]
- Waardenburg syndromes are characterized by pigmentation and autosensory hearing defects, and mutations in genes encoding transcription factors that control neural crest specification and differentiation are often associa...
|