- Identification of the molecular chaperone, heat shock protein 1 (chaperonin 10), in the reproductive tract and in capacitating spermatozoa in the male mouse
[作者:Walsh, A; Whelan, D; Bielanowicz, A; Skinner, B; Aitken, RJ; O'Bryan, MK; Nixon, B,期刊:Biology of Reproduction, 页码:983-993 , 文章类型: Article,,卷期:2008年78-6]
- Mammalian spermatozoa must undergo epididymal maturation in the male reproductive tract and capacitation in the female tract before acquiring the ability to fertilize an oocyte. Previous studies from our laboratory have ...
- Functional redundancy of TGF-beta family type receptors and receptor-smads in mediating anti-Mullerian hormone-induced Mullerian duct regression in the mouse
[作者:Orvis, GD; Jamin, SP; Kwan, KM; Mishina, Y; Kaartinen, VM; Huang, S; Roberts, AB; Umans, L; Huylebroeck, D; Zwijsen, A; Wang, D; Martin, JF; Behringer, RR,期刊:Biology of Reproduction, 页码:994-1001 , 文章类型: Article,,卷期:2008年78-6]
- Amniotes, regardless of genetic sex, develop two sets of genital ducts: the Wolffian and Mulerian ducts. For normal sexual development to occur, one duct must differentiate into its corresponding organs, and the other mu...
- Regulated expression of ADAM8 (a disintegrin and metalloprotease domain 8) in the mouse ovary: Evidence for a regulatory role of luteinizing hormone, progesterone receptor, and epidermal growth factor-like growth factors
[作者:Sriraman, V; Eichenlaub-Ritter, U; Bartsch, JW; Rittger, A; Mulders, SM; Richards, JS,期刊:Biology of Reproduction, 页码:1038-1048 , 文章类型: Article,,卷期:2008年78-6]
- ADAM8 (a disintegrin and metalloprotease domain 8) is expressed in immune, neuronal, and bone progenitor cells and is thought to be involved in the tissue-remodeling process. Microarray analyses indicate that Adam8 is a ...
- Abortion in mice with excessive erythrocytosis is due to impaired arteriogenesis of the uterine arcade
[作者:Gassmann, M; Manini, A; Stallmach, T; Saam, B; Kuhn, G; Grenacher, B; Bogdanova, AY; Vogel, J,期刊:Biology of Reproduction, 页码:1049-1057 , 文章类型: Article,,卷期:2008年78-6]
- We postulate that repeated pregnancy loss, intrauterine growth restriction, and preeclampsia are caused by impaired elevation of uterine blood flow due to disturbed arteriogenesis of the uterine arcade. This hypothesis i...
- Overexpression of SK3 channels dampens uterine contractility to prevent preterm laborin mice
[作者:Pierce, SL; Kresowik, JDK; Lamping, KG; England, SK,期刊:Biology of Reproduction, 页码:1058-1063 , 文章类型: Article,,卷期:2008年78-6]
- The mechanisms that control the timing of labor have yet to befully characterized. in a previous study, the overexpression of small conductance calcium-activated K+ channel isoform 3 in transgenic mice, Kcnn3(tm1Jpad)/Kc...
- Prm3, the fourth gene in the mouse protamine gene cluster, encodes a conserved acidic protein that affects sperm motility
[作者:Grzmil, P; Boinska, D; Kleene, KC; Adham, I; Schluter, G; Kamper, M; Buyandelger, B; Meinhardt, A; Wolf, S; Engel, W,期刊:Biology of Reproduction, 页码:958-967 , 文章类型: Article,,卷期:2008年78-6]
- The protamine gene cluster containing the Prm1, Prm2, Prm3, and Tnp2 genes is present in humans, mice, and rats. The Prm1, Prm2, and Tnp2 genes have been extensively studied, but almost nothing is known about the functio...
- Gamendazole, an orally active indazole carboxylic acid male contraceptive agent, targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and stimulates Il1a transcription in rat sertoli cells
[作者:Tash, JS; Chakrasali, R; Jakkaraj, SR; Hughes, J; Smith, SK; Hornbaker, K; Heckert, LL; Ozturk, SB; Hadden, MK; Kinzy, TG; Blagg, BSJ; Georg, GI,期刊:Biology of Reproduction, 页码:1139-1152 , 文章类型: Article,,卷期:2008年78-6]
- Gamendazole was recently identified as an orally active antispermatogenic compound with antifertility effects. The cellular mechanism(s) through which these effects occur and the molecular target(s) of gamendazole action...
- Multiple signals regulate phospholipase CBeta3 in human myometrial cells
[作者:Zhong, M; Murtazina, DA; Phillips, J; Ku, CY; Sanborn, BA,期刊:Biology of Reproduction, 页码:1007-1017 , 文章类型: Article,,卷期:2008年78-6]
- Phospholipase CB3 (PLCB3) serine(1105) (S-1105), a substrate for multiple protein kinases, represents a potential point of convergence of several signaling pathways in the myometrium. To explore this hypothesis, the regu...
- Matrix metalloproteinase 9 (MMP9) expression in preeclamptic decidua and MMP9 induction by tumor necrosis factor alpha and interleukin 1 beta in human first trimester decidual cells
[作者:Lockwood, CJ; Oner, C; Uz, YH; Kayisli, UA; Huang, SJ; Buchwalder, LF; Murk, W; Funai, EF; Schatz, F,期刊:Biology of Reproduction, 页码:1064-1072 , 文章类型: Article,,卷期:2008年78-6]
- Extravillous trophoblasts (EVTs) invade human decidua via sequential integrin-mediated binding and proteolysis of basement membrane proteins in the extracellular matrix (ECM). In preeclampsia, shallow EVT invasion impair...
- Endoglin (CD105) expression is regulated by the liver X receptor alpha (NR1H3) in human trophoblast cell line JAR
[作者:Henry-Berger, J; Mouzat, K; Baron, S; Bernabeu, C; Marceau, G; Saru, JP; Sapin, V; Lobaccaro, JMA; Caira, F,期刊:Biology of Reproduction, 页码:968-975 , 文章类型: Article,,卷期:2008年78-6]
- Human implantation involves invasion of the uterine wall and remodeling of uterine arteries by extravillous cytotrophoblasts. Defects in these early steps of placental development lead to poor placentation and are often ...
- In utero exposure to di-(2-ethylhexyl) phthalate exerts both short-term and long-lasting suppressive effects on testosterone production in the rat
[作者:Culty, M; Thuillier, R; Li, WP; Wang, Y; Martinez-Arguelles, DB; Benjamin, CG; Triantafilou, KM; Zirkin, BR; Papadopoulos, V,期刊:Biology of Reproduction, 页码:1018-1028 , 文章类型: Article,,卷期:2008年78-6]
- We examined the effects of fetal exposure to a wide range of di-(2-ethylhexyl) phthalate (DEHP) doses on fetal, neonatal, and adult testosterone production. Pregnant rats were administered DEHP from Gestational Day (GD) ...
|