- Structure of the Enterococcus faecalis EIIA(gnt) PTS component
[作者:Reinelt, S; Koch, B; Hothorn, M; Hengstenberg, W; Welti, S; Scheffzek, K,期刊:Biochemical and Biophysical Research Communications, 页码:626-629 , 文章类型: Article,,卷期:2009年388-4]
- In Eubacteria, the utilization of a number of extracellular carbohydrates is mediated by sugar specific phosphoenolepyruvate ( PEP) dependent sugar phosphotransferase systems (PTSs), which simultaneously import und phosp...
- Activity of the Enterococcus faecalis EIIA(gnt) PTS component and its strong interaction with EIIBgnt
[作者:Brockmeier, A; Skopnik, M; Koch, B; Herrmann, C; Hengstenberg, W; Welti, S; Scheffzek, K,期刊:Biochemical and Biophysical Research Communications, 页码:630-636 , 文章类型: Article,,卷期:2009年388-4]
- Eubacteria can import and simultaneously phosphorylate a range of different carbohydrates by means of sugar specific phosphoenolpyruvate (PEP) dependent sugar phosphotransferase systems (PTSs). Here, we report the bioche...
- The ER-membrane-resident Hsp40 ERj1 is a novel substrate for protein kinase CK2
[作者:Gotz, C; Muller, A; Montenarh, M; Zimmermann, R; Dudek, J,期刊:Biochemical and Biophysical Research Communications, 页码:637-642 , 文章类型: Article,,卷期:2009年388-4]
- The endoplasmic reticulum ( ER) membrane protein ERj1, a member of the Hsp40 family, was proposed to be a regulator of protein biogenesis at the ER. With its lumenal J-domain, ERj1 recruits the lumenal Hsp70-type chapero...
- Statins, fibrates and retinoic acid upregulate mitochondrial acylcarnitine carrier gene expression
[作者:Iacobazzi, V; Convertini, P; Infantino, V; Scarcia, P; Todisco, S; Palmieri, F,期刊:Biochemical and Biophysical Research Communications, 页码:643-647 , 文章类型: Article,,卷期:2009年388-4]
- In this study, we investigated the effects of statins, fibrates, 9-cis-retinoic acid and forskolin on the transcription of the mitochondrial carnitine/acylcarnitine carrier (CAC) gene. Statins, fibrates, retinoic acid an...
- Rev-erb beta regulates the Srebp-1c promoter and mRNA expression in skeletal muscle cells
[作者:Ramakrishnan, SN; Lau, P; Crowther, LM; Cleasby, ME; Millard, S; Leong, GM; Cooney, GJ; Muscat, GEO,期刊:Biochemical and Biophysical Research Communications, 页码:654-659 , 文章类型: Article,,卷期:2009年388-4]
- The nuclear hormone receptor, Rev-erb beta operates as a transcriptional silencer. We previously demonstrated that exogenous expression of Rev-erb beta Delta E in skeletal muscle cells increased Srebp-1c mRNA expression....
- The conjugated linoleic acid isomer trans-9, trans-11 is a dietary occurring agonist of liver X receptor alpha
[作者:Ecker, J; Liebisch, G; Patsch, W; Schmitz, G,期刊:Biochemical and Biophysical Research Communications, 页码:660-666 , 文章类型: Article,,卷期:2009年388-4]
- Conjugated linoleic acid (CLA) isomers are dietary fatty acids that modulate gene expression in many cell types. We have previously reported that specifically trans-9, trans-11 (t9, t11)-CLA induces expression of genes i...
- Novel protein engineering strategy for creating highly receptor-selective mutant TNFs
[作者:Nomura, T; Abe, Y; Kamada, H; Inoue, M; Kawara, T; Arita, S; Furuya, T; Yoshioka, Y; Shibata, H; Kayamuro, H; Yamashita, T; Nagano, K; Yoshikawa, T; Mukai, Y; Nakagawa, S; Taniai, M; Ohta, T; Tsunoda, S; Tsutsumi, Y,期刊:Biochemical and Biophysical Research Communications, 页码:667-671 , 文章类型: Article,,卷期:2009年388-4]
- Tumor necrosis factor (TNF) plays important roles in host defense and in preventing tumor formation by acting via its receptors, TNFR1 and TNFR2, functions of which are less understood. To this end, we have been isolatin...
- Inhibition of human P-glycoprotein transport and substrate binding using a galantamine dimer
[作者:Namanja, HA; Emmert, D; Pires, MM; Hrycyna, CA; Chmielewski, J,期刊:Biochemical and Biophysical Research Communications, 页码:672-676 , 文章类型: Article,,卷期:2009年388-4]
- The human multidrug resistance transporter P-glycoprotein (P-gp) prevents the entry of compounds into the brain by an active efflux mechanism at the blood-brain barrier (BBB). Treatment of neurodegenerative diseases, the...
- Internalization of MUC1 by anti-MUC1 antibody from cell membrane through the macropinocytotic pathway
[作者:Hisatsune, A; Kawasaki, M; Nakayama, H; Mikami, Y; Miyata, T; Isohama, Y; Katsuki, H; Kim, KC,期刊:Biochemical and Biophysical Research Communications, 页码:677-682 , 文章类型: Article,,卷期:2009年388-4]
- MUC1 is a type I transmembrane glycoprotein aberrantly overexpressed in various cancer cells. It is thought to serve as a physical barrier from the extracellular environment and also as a receptor for various extracellul...
- Analysis of the role of the HIF hydroxylase family members in erythropoiesis
[作者:Fisher, TS; Lira, PD; Stock, JL; Perregaux, DG; Brissette, WH; Ozolins, TRS; Li, BY,期刊:Biochemical and Biophysical Research Communications, 页码:683-688 , 文章类型: Article,,卷期:2009年388-4]
- HIF (hypoxia-inducible factor) hydroxylases have been implicated in EPO (erythropoietin) production and erythropoiesis. Here we examined the role of each of the three EGLN family members and the HIF asparaginyl hydroxyla...
- KAP1-independent transcriptional repression of SCAN-KRAB-containing zinc finger proteins
[作者:Itokawa, Y; Yanagawa, T; Yamakawa, H; Watanabe, N; Koga, H; Nagase, T,期刊:Biochemical and Biophysical Research Communications, 页码:689-694 , 文章类型: Article,,卷期:2009年388-4]
- The Kruppel-associated box-containing zinc finger gene family (KRAB-ZNF) is one of the largest gene families of transcriptional factors in the human genome. Although the functions of most of these genes remain to be dete...
- Bcl-2 inhibitor and apigenin worked synergistically in human malignant neuroblastoma cell lines and increased apoptosis with activation of extrinsic and intrinsic pathways
[作者:Karmakar, S; Davis, KA; Choudhury, SR; Deeconda, A; Banik, NL; Ray, SK,期刊:Biochemical and Biophysical Research Communications, 页码:705-710 , 文章类型: Article,,卷期:2009年388-4]
- Neuroblastoma is the most common extracranial solid tumor in infants and young children. Current treatments are not always effective and new therapies are needed. We examined efficacy of combination of the small molecule...
- Gene targeting in human pluripotent stem cells with adeno-associated virus vectors
[作者:Mitsui, K; Suzuki, K; Aizawa, E; Kawase, E; Suemori, H; Nakatsuji, N; Mitani, K,期刊:Biochemical and Biophysical Research Communications, 页码:711-717 , 文章类型: Article,,卷期:2009年388-4]
- Human pluripotent stem cells, such as embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs), have the ability to differentiate into various cell types, and will become a potential source of cellular ma...
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