- Full-length Escherichia coli SecA Dimerizes in a Closed Conformation in Solution as Determined by Cryo-electron Microscopy
[作者:Chen, Y; Pan, XJ; Tang, Y; Quan, S; Tai, PC; Sui, SF,期刊:Journal of Biological Chemistry, 页码:28783-28787 , 文章类型: Article,,卷期:2008年283-43]
- SecA is an obligatory component of the Escherichia coli general secretion pathway. However, the oligomeric structure of SecA and SecA conformational changes during translocation processes are still unclear. Here we obtai...
- PqsD Is Responsible for the Synthesis of 2,4-Dihydroxyquinoline, an Extracellular Metabolite Produced by Pseudomonas aeruginosa
[作者:Zhang, YM; Frank, MW; Zhu, K; Mayasundari, A; Rock, CO,期刊:Journal of Biological Chemistry, 页码:28788-28794 , 文章类型: Article,,卷期:2008年283-43]
- 2,4-Dihydroxyquinoline (DHQ) is an abundant extracellular metabolite of the opportunistic pathogen Pseudomonas aeruginosa that is secreted into growth medium in stationary phase to concentrations comparable with those of...
- The G(i)-coupled P2Y12 Receptor Regulates Diacylglycerol-mediated Signaling in Human Platelets
[作者:Guidetti, GF; Lova, P; Bernardi, B; Campus, F; Baldanzi, G; Graziani, A; Balduini, C; Torti, M,期刊:Journal of Biological Chemistry, 页码:28795-28805 , 文章类型: Article,,卷期:2008年283-43]
- Stimulation of G(q)-coupled receptors activates phospholipase C and is supposed to promote both intracellular Ca2+ mobilization and protein kinase C (PKC) activation. We found that ADP-induced phosphorylation of pleckstr...
- TDP-43 Overexpression Enhances Exon 7 Inclusion during the Survival of Motor Neuron Pre-mRNA Splicing
[作者:Bose, JK; Wang, IF; Hung, L; Tarn, WY; Shen, CKJ,期刊:Journal of Biological Chemistry, 页码:28852-28859 , 文章类型: Article,,卷期:2008年283-43]
- TDP-43 is a highly conserved, 43-kDa RNA-binding protein implicated to play a role in transcription repression, nuclear organization, and alternative splicing. More recently, this factor has been identified as the major ...
- A Novel Splicing Variant of Mouse Interleukin (IL)-24 Antagonizes IL-24-induced Apoptosis
[作者:Sahoo, A; Jung, YM; Kwon, HK; Yi, HJ; Lee, S; Chang, S; Park, ZY; Hwang, KC; Im, SH,期刊:Journal of Biological Chemistry, 页码:28860-28872 , 文章类型: Article,,卷期:2008年283-43]
- Alternative splicing of mRNA enables functionally diverse protein isoforms to be expressed from a single gene, allowing transcriptome diversification. Interleukin (IL)-24/MDA-7 is a member of the IL-10 gene family, and F...
- Cooperative Synergy between NFAT and MyoD Regulates Myogenin Expression and Myogenesis
[作者:Armand, AS; Bourajjaj, M; Martinez-Martinez, S; el Azzouzi, H; Martins, PAD; Hatzis, P; Seidler, T; Redondo, JM; De Windt, LJ,期刊:Journal of Biological Chemistry, 页码:29004-29010 , 文章类型: Article,,卷期:2008年283-43]
- Calcineurin/NFAT signaling is involved in multiple aspects of skeletal muscle development and disease. The myogenic basic helix-loop-helix transcription factors, MyoD, myogenin, Myf5, and MRF4 specify the myogenic lineag...
- The psbo1 Mutant of Arabidopsis Cannot Efficiently Use Calcium in Support of Oxygen Evolution by Photosystem II
[作者:Bricker, TM; Frankel, LK,期刊:Journal of Biological Chemistry, 页码:29022-29027 , 文章类型: Article,,卷期:2008年283-43]
- The Arabidopsis thaliana mutant psbo1 contains a point mutation in the psbO-1 gene (At5g66570) leading to the loss of expression of the PsbO-1 protein and overexpression of the PsbO-2 protein (Murakami, R., Ifuku, K., Ta...
- A Novel Protein Kinase A-independent, beta-Arrestin-1-dependent Signaling Pathway for p38 Mitogen-activated Protein Kinase Activation by beta(2)-Adrenergic Receptors
[作者:Gong, KZ; Li, ZJ; Xu, M; Du, JH; Lv, ZZ; Zhang, YY,期刊:Journal of Biological Chemistry, 页码:29028-29036 , 文章类型: Article,,卷期:2008年283-43]
- A growing body of evidence has demonstrated that p38 mitogen-activated protein kinase (MAPK) has a crucial role in various physiological and pathological processes mediated by beta(2)-adrenergic receptors (beta(2)-ARs). ...
- CDK Inhibitor p21 Is Degraded by a Proliferating Cell Nuclear Antigen-coupled Cul4-DDB1(Cdt2) Pathway during S Phase and after UV Irradiation
[作者:Nishitani, H; Shiomi, Y; Iida, H; Michishita, M; Takami, T; Tsurimoto, T,期刊:Journal of Biological Chemistry, 页码:29045-29052 , 文章类型: Article,,卷期:2008年283-43]
- Previous reports showed that chromatin-associated PCNA couples DNA replication with Cul4-DDB1(Cdt2)-dependent proteolysis of the licensing factor Cdt1. The CDK inhibitor p21, another PCNA-binding protein, is also degrade...
- Irreversible Oxidation of the Active-site Cysteine of Peroxiredoxin to Cysteine Sulfonic Acid for Enhanced Molecular Chaperone Activity
[作者:Lim, JC; Choi, HI; Park, YS; Nam, HW; Woo, HA; Kwon, KS; Kim, YS; Rhee, SG; Kim, K; Chae, HZ,期刊:Journal of Biological Chemistry, 页码:28873-28880 , 文章类型: Article,,卷期:2008年283-43]
- The thiol (-SH) of the active cysteine residue in peroxiredoxin (Prx) is known to be reversibly hyperoxidized to cysteine sulfinic acid (-SO2H), which can be reduced back to thiol by sulfiredoxin/sestrin. However, hypero...
|