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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共18条记录   Downregulation of Thrombomodulin, a Novel Target of Snail, Induces Tumorigenesis through Epithelial-Mesenchymal Transition [作者：Kao, YC; Wu, LW; Shi, CS; Chu, CH; Huang, CW; Kuo, CP; Sheu, HM; Shi, GY; Wu, HL,期刊：Molecular and Cellular Biology, 页码：4767-4785 , 文章类型： Article，,卷期：2010年30-20] The expression of thrombomodulin (TM), a calcium-dependent adhesion molecule, is frequently downregulated in various cancer types. However, the mechanism responsible for the low expression level of TM in tumorigenesis is... RhoA Phosphorylation Induces Rac1 Release from Guanine Dissociation Inhibitor alpha and Stimulation of Vascular Smooth Muscle Cell Migration [作者：Rolli-Derkinderen, M; Toumaniantz, G; Pacaud, P; Loirand, G,期刊：Molecular and Cellular Biology, 页码：4786-4796 , 文章类型： Article，,卷期：2010年30-20] Although overactivation of RhoA is recognized as a common component of vascular disorders, the molecular mechanisms regulating RhoA activity in vascular smooth muscle cells (VSMC) are still unclear. We have previously sh... The Atypical Homeodomain Transcription Factor Mohawk Controls Tendon Morphogenesis [作者：Liu, WJ; Watson, SS; Lan, Y; Keene, DR; Ovitt, CE; Liu, H; Schweitzer, R; Jiang, RL,期刊：Molecular and Cellular Biology, 页码：4797-4807 , 文章类型： Article，,卷期：2010年30-20] The Mohawk homeobox (Mkx) gene encodes a new atypical homeodomain-containing protein with transcriptional repressor activity. Mkx mRNA exhibited dynamic expression patterns during development of the palate, somite, kidne... Molecular Dissection of Telomeric Repeat-Containing RNA Biogenesis Unveils the Presence of Distinct and Multiple Regulatory Pathways [作者：Porro, A; Feuerhahn, S; Reichenbach, P; Lingner, J,期刊：Molecular and Cellular Biology, 页码：4808-4817 , 文章类型： Article，,卷期：2010年30-20] Telomeres are transcribed into telomeric repeat-containing RNA (TERRA), large, heterogeneous, non-coding transcripts which form part of the telomeric heterochromatin. Despite a large number of functions that have been as... The Transcriptional Mediator Subunit MED1/TRAP220 in Stromal Cells Is Involved in Hematopoietic Stem/Progenitor Cell Support through Osteopontin Expression [作者：Sumitomo, A; Ishino, R; Urahama, N; Inoue, K; Yonezawa, K; Hasegawa, N; Horie, O; Matsuoka, H; Kondo, T; Roeder, RG; Ito, M,期刊：Molecular and Cellular Biology, 页码：4818-4827 , 文章类型： Article，,卷期：2010年30-20] MED1/TRAP220, a subunit of the transcriptional Mediator/TRAP complex, is crucial for various biological events through its interaction with distinct activators, such as nuclear receptors and GATA family activators. In he... Replication Factor C Recruits DNA Polymerase delta to Sites of Nucleotide Excision Repair but Is Not Required for PCNA Recruitment [作者：Overmeer, RM; Gourdin, AM; Giglia-Mari, A; Kool, H; Houtsmuller, AB; Siegal, G; Fousteri, MI; Mullenders, LHF; Vermeulen, W,期刊：Molecular and Cellular Biology, 页码：4828-4839 , 文章类型： Article，,卷期：2010年30-20] Nucleotide excision repair (NER) operates through coordinated assembly of repair factors into pre- and postincision complexes. The postincision step of NER includes gap-filling DNA synthesis and ligation. However, the ex... Srs2 Plays a Critical Role in Reversible G(2) Arrest upon Chronic and Low Doses of UV Irradiation via Two Distinct Homologous Recombination-Dependent Mechanisms in Postreplication Repair-Deficient Cells [作者：Hishida, T; Hirade, Y; Haruta, N; Kubota, Y; Iwasaki, H,期刊：Molecular and Cellular Biology, 页码：4840-4850 , 文章类型： Article，,卷期：2010年30-20] Differential posttranslational modification of proliferating cell nuclear antigen (PCNA) by ubiquitin or SUMO plays an important role in coordinating the processes of DNA replication and DNA damage tolerance. Previously ... Lysine-Specific Demethylase 1 Regulates the Embryonic Transcriptome and CoREST Stability [作者：Foster, CT; Dovey, OM; Lezina, L; Luo, JL; Gant, TW; Barlev, N; Bradley, A; Cowley, SM,期刊：Molecular and Cellular Biology, 页码：4851-4863 , 文章类型： Article，,卷期：2010年30-20] Lysine-specific demethylase 1 (LSD1), which demethylates mono-and dimethylated histone H3-Lys4 as part of a complex including CoREST and histone deacetylases (HDACs), is essential for embryonic development in the mouse b... Cellular Prion Protein Promotes Regeneration of Adult Muscle Tissue [作者：Stella, R; Massimino, ML; Sandri, M; Sorgato, MC; Bertoli, A,期刊：Molecular and Cellular Biology, 页码：4864-4876 , 文章类型： Article，,卷期：2010年30-20] It is now well established that the conversion of the cellular prion protein, PrPC, into its anomalous conformer, PrPSc, is central to the onset of prion disease. However, both the mechanism of prion-related neurodegener... CD69 Association with Jak3/Stat5 Proteins Regulates Th17 Cell Differentiation [作者：Martin, P; Gomez, M; Lamana, A; Cruz-Adalia, A; Ramirez-Huesca, M; Ursa, MA; Yanez-Mo, M; Sanchez-Madrid, F,期刊：Molecular and Cellular Biology, 页码：4877-4889 , 文章类型： Article，,卷期：2010年30-20] T-cell differentiation involves the early decision to commit to a particular pattern of response to an antigen. Here, we show that the leukocyte activation antigen CD69 limits differentiation into proinflammatory help... Stimulation of Sirt1-Regulated FoxO Protein Function by the Ligand-Bound Vitamin D Receptor [作者：An, BS; Tavera-Mendoza, LE; Dimitrov, V; Wang, XF; Calderon, MR; Wang, HJ; White, JH,期刊：Molecular and Cellular Biology, 页码：4890-4900 , 文章类型： Article，,卷期：2010年30-20] Hormonal vitamin D, 1,25-dihydroxyvitamin D (1,25D), signals through the nuclear vitamin D receptor (VDR). 1,25D regulates cell proliferation and differentiation and has been identified as a cancer chemopreventive agent.... Mechanism of Hypoxia-Induced NF-kappa B [作者：Culver, C; Sundqvist, A; Mudie, S; Melvin, A; Xirodimas, D; Rocha, S,期刊：Molecular and Cellular Biology, 页码：4901-4921 , 文章类型： Article，,卷期：2010年30-20] NF-kappa B activation is a critical component in the transcriptional response to hypoxia. However, the underlying mechanisms that control its activity under these conditions are unknown. Here we report that under hypoxic... Cell-Type-Specific Activation and Repression of PU.1 by a Complex of Discrete, Functionally Specialized cis-Regulatory Elements [作者：Zarnegar, MA; Chen, J; Rothenberg, EV,期刊：Molecular and Cellular Biology, 页码：4922-4939 , 文章类型： Article，,卷期：2010年30-20] The transcription factor PU.1 is critical for multiple hematopoietic lineages, but different leukocyte types require strictly distinct patterns of PU.1 regulation. PU.1 is required early for T-cell lineage development bu... Dosage-Sensitive Regulation of Cohesin Chromosome Binding and Dynamics by Nipped-B, Pds5, and Wapl [作者：Gause, M; Misulovin, Z; Bilyeu, A; Dorsett, D,期刊：Molecular and Cellular Biology, 页码：4940-4951 , 文章类型： Article，,卷期：2010年30-20] The cohesin protein complex holds sister chromatids together to ensure proper chromosome segregation upon cell division and also regulates gene transcription. Partial loss of the Nipped-B protein that loads cohesin onto ... Regulation of Nucleolar Chromatin by B23/Nucleophosmin Jointly Depends upon Its RNA Binding Activity and Transcription Factor UBF [作者：Hisaoka, M; Ueshima, S; Murano, K; Nagata, K; Okuwaki, M,期刊：Molecular and Cellular Biology, 页码：4952-4964 , 文章类型： Article，,卷期：2010年30-20] Histone chaperones regulate the density of incorporated histone proteins around DNA transcription sites and therefore constitute an important site-specific regulatory mechanism for the control of gene expression. At pres... Tetrahymena Telomerase Protein p65 Induces Conformational Changes throughout Telomerase RNA (TER) and Rescues Telomerase Reverse Transcriptase and TER Assembly Mutants [作者：Berman, AJ; Gooding, AR; Cech, TR,期刊：Molecular and Cellular Biology, 页码：4965-4976 , 文章类型： Article，,卷期：2010年30-20] The biogenesis of the Tetrahymena telomerase ribonucleoprotein particle (RNP) is enhanced by p65, a La family protein. Single-molecule and biochemical studies have uncovered a hierarchical assembly of the RNP, wherein th...