- Endocytosis of the Aspartic Acid/Glutamic Acid Transporter Dip5 Is Triggered by Substrate-Dependent Recruitment of the Rsp5 Ubiquitin Ligase via the Arrestin-Like Protein Aly2
[作者：Hatakeyama, R; Kamiya, M; Takahara, T; Maeda, T,期刊：Molecular and Cellular Biology, 页码：5598-5607 , 文章类型： Article，,卷期：2010年30-24]
- Endocytosis of nutrient transporters is stimulated under various conditions, such as elevated nutrient availability. In Saccharomyces cerevisiae, endocytosis is triggered by ubiquitination of transporters catalyzed by th...
- Anaphase-Promoting Complex/Cyclosome Participates in the Acute Response to Protein-Damaging Stress
[作者：Ahlskog, JK; Bjork, JK; Elsing, AN; Aspelin, C; Kallio, M; Roos-Mattjus, P; Sistonen, L,期刊：Molecular and Cellular Biology, 页码：5608-5620 , 文章类型： Article，,卷期：2010年30-24]
- The ubiquitin E3 ligase anaphase-promoting complex/cyclosome (APC/C) drives degradation of cell cycle regulators in cycling cells by associating with the coactivators Cdc20 and Cdh1. Although a plethora of APC/C substrat...
- Pygo2 Associates with MLL2 Histone Methyltransferase and GCN5 Histone Acetyltransferase Complexes To Augment Wnt Target Gene Expression and Breast Cancer Stem-Like Cell Expansion
[作者：Chen, JK; Luo, QC; Yuan, YY; Huang, XL; Cai, WY; Li, C; Wei, TZ; Zhang, LD; Yang, M; Liu, QF; Ye, GD; Dai, X; Li, BA,期刊：Molecular and Cellular Biology, 页码：5621-5635 , 文章类型： Article，,卷期：2010年30-24]
- Resent studies have identified Pygopus as a core component of the beta-catenin/T-cell factor (TCF)/lymphoid-enhancing factor 1 (LEF) transcriptional activation complex required for the expression of canonical Wg/Wnt targ...
- Genome-Wide Profiling of the Core Clock Protein BMAL1 Targets Reveals a Strict Relationship with Metabolism
[作者：Hatanaka, F; Matsubara, C; Myung, J; Yoritaka, T; Kamimura, N; Tsutsumi, S; Kanai, A; Suzuki, Y; Sassone-Corsi, P; Aburatani, H; Sugano, S; Takumi, T,期刊：Molecular and Cellular Biology, 页码：5636-5648 , 文章类型： Article，,卷期：2010年30-24]
- Circadian rhythms are common to most organisms and govern much of homeostasis and physiology. Since a significant fraction of the mammalian genome is controlled by the clock machinery, understanding the genome-wide signa...
- Cytosolic Ras Supports Eye Development in Drosophila
[作者：Sung, PJ; Rodrigues, AB; Kleinberger, A; Quatela, S; Bach, EA; Philips, MR,期刊：Molecular and Cellular Biology, 页码：5649-5657 , 文章类型： Article，,卷期：2010年30-24]
- Ras proteins associate with cellular membranes as a consequence of a series of posttranslational modifications of a C-terminal CAAX sequence that include prenylation and are thought to be required for biological activity...
- CPEB4 Is a Cell Survival Protein Retained in the Nucleus upon Ischemia or Endoplasmic Reticulum Calcium Depletion
[作者：Kan, MC; Oruganty-Das, A; Cooper-Morgan, A; Jin, GA; Swanger, SA; Bassell, GJ; Florman, H; van Leyen, K; Richter, JD,期刊：Molecular and Cellular Biology, 页码：5658-5671 , 文章类型： Article，,卷期：2010年30-24]
- The RNA binding protein CPEB (cytoplasmic polyadenylation element binding) regulates cytoplasmic polyadenylation and translation in germ cells and the brain. In neurons, CPEB is detected at postsynaptic sites, as well as...
- Nbr1 Is a Novel Inhibitor of Ligand-Mediated Receptor Tyrosine Kinase Degradation
[作者：Mardakheh, FK; Auciello, G; Dafforn, TR; Rappoport, JZ; Heath, JK,期刊：Molecular and Cellular Biology, 页码：5672-5685 , 文章类型： Article，,卷期：2010年30-24]
- Neighbor of BRCA1 (Nbr1) is a highly conserved multidomain scaffold protein with proposed roles in endocytic trafficking and selective autophagy. However, the exact function of Nbr1 in these contexts has not been studied...
- The Mammalian Sin3 Proteins Are Required for Muscle Development and Sarcomere Specification
[作者：van Oevelen, C; Bowman, C; Pellegrino, J; Asp, P; Cheng, JM; Parisi, F; Micsinai, M; Kluger, Y; Chu, A; Blais, A; David, G; Dynlacht, BD,期刊：Molecular and Cellular Biology, 页码：5686-5697 , 文章类型： Article，,卷期：2010年30-24]
- The highly related mammalian Sin3A and Sin3B proteins provide a versatile platform for chromatin-modifying activities. Sin3-containing complexes play a role in gene repression through deacetylation of nucleosomes. Here, ...
- Cdk1/Cyclin B1 Controls Fas-Mediated Apoptosis by Regulating Caspase-8 Activity
[作者：Matthess, Y; Raab, M; Sanhaji, M; Lavrik, IN; Strebhardt, K,期刊：Molecular and Cellular Biology, 页码：5726-5740 , 文章类型： Article，,卷期：2010年30-24]
- Caspase activation is a hallmark of apoptosis. However, the molecular mechanisms underlying the regulation of caspase-8 activation within the extrinsic death pathway are not well understood. In this study, we demonstrate...
- cis-Regulatory Remodeling of the SCL Locus during Vertebrate Evolution
[作者：Gottgens, B; Ferreira, R; Sanchez, MJ; Ishibashi, S; Li, JA; Spensberger, D; Lefevre, P; Ottersbach, K; Chapman, M; Kinston, S; Knezevic, K; Hoogenkamp, M; Follows, GA; Bonifer, C; Amaya, E; Green, AR,期刊：Molecular and Cellular Biology, 页码：5741-5751 , 文章类型： Article，,卷期：2010年30-24]
- Development progresses through a sequence of cellular identities which are determined by the activities of networks of transcription factor genes. Alterations in cis-regulatory elements of these genes play a major role i...
- Targeted Inactivation of Mapk4 in Mice Reveals Specific Nonredundant Functions of Erk3/Erk4 Subfamily Mitogen-Activated Protein Kinases
[作者：Rousseau, J; Klinger, S; Rachalski, A; Turgeon, B; Deleris, P; Vigneault, E; Poirier-Heon, JF; Davoli, MA; Mechawar, N; El Mestikawy, S; Cermakian, N; Meloche, S,期刊：Molecular and Cellular Biology, 页码：5752-5763 , 文章类型： Article，,卷期：2010年30-24]
- Erk4 and Erk3 are atypical members of the mitogen-activated protein ( MAP) kinase family. The high sequence identity of Erk4 and Erk3 proteins and the similar organization of their genes imply that the two protein kinase...
- Sipl1 and Rbck1 Are Novel Eya1-Binding Proteins with a Role in Craniofacial Development
[作者：Landgraf, K; Bollig, F; Trowe, MO; Besenbeck, B; Ebert, C; Kruspe, D; Kispert, A; Hanel, F; Englert, C,期刊：Molecular and Cellular Biology, 页码：5764-5775 , 文章类型： Article，,卷期：2010年30-24]
- The eyes absent 1 protein (Eya1) plays an essential role in the development of various organs in both invertebrates and vertebrates. Mutations in the human EYA1 gene are linked to BOR (branchio-oto-renal) syndrome, chara...
- Requirement of the ATM/p53 Tumor Suppressor Pathway for Glucose Homeostasis
[作者：Armata, HL; Golebiowski, D; Jung, DY; Ko, HJ; Kim, JK; Sluss, HK,期刊：Molecular and Cellular Biology, 页码：5787-5794 , 文章类型： Article，,卷期：2010年30-24]
- Ataxia telangiectasia (A-T) patients can develop multiple clinical pathologies, including neuronal degeneration, an elevated risk of cancer, telangiectasias, and growth retardation. Patients with A-T can also exhibit an ...
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