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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共27条记录   Rac1 Is Essential for Basement Membrane-Dependent Epiblast Survival [作者：He, XW; Liu, J; Qi, YM; Brakebusch, C; Chrostek-Grashoff, A; Edgar, D; Yurchenco, PD; Corbett, SA; Lowry, SF; Graham, AM; Han, YL; Li, SH,期刊：Molecular and Cellular Biology, 页码：3569-3581 , 文章类型： Article，,卷期：2010年30-14] During murine peri-implantation development, the egg cylinder forms from a solid cell mass by the apoptotic removal of inner cells that do not contact the basement membrane (BM) and the selective survival of the epiblast... MOF and Histone H4 Acetylation at Lysine 16 Are Critical for DNA Damage Response and Double-Strand Break Repair [作者：Sharma, GG; So, S; Gupta, A; Kumar, R; Cayrou, C; Avvakumov, N; Bhadra, U; Pandita, RK; Porteus, MH; Chen, DJ; Cote, J; Pandita, TK,期刊：Molecular and Cellular Biology, 页码：3582-3595 , 文章类型： Article，,卷期：2010年30-14] The human MOF gene encodes a protein that specifically acetylates histone H4 at lysine 16 (H4K16ac). Here we show that reduced levels of H4K16ac correlate with a defective DNA damage response (DDR) and double-strand brea... Ror2/Frizzled Complex Mediates Wnt5a-Induced AP-1 Activation by Regulating Dishevelled Polymerization [作者：Nishita, M; Itsukushima, S; Nomachi, A; Endo, M; Wang, ZC; Inaba, D; Qiao, S; Takada, S; Kikuchi, A; Minami, Y,期刊：Molecular and Cellular Biology, 页码：3610-3619 , 文章类型： Article，,卷期：2010年30-14] The receptor tyrosine kinase Ror2 acts as a receptor or coreceptor for Wnt5a to mediate Wnt5a-induced activation of the Wnt/JNK pathway and inhibition of the beta-catenin-dependent canonical Wnt pathway. However, little ... miR-31 Functions as a Negative Regulator of Lymphatic Vascular Lineage-Specific Differentiation In Vitro and Vascular Development In Vivo [作者：Pedrioli, DML; Karpanen, T; Dabouras, V; Jurisic, G; van de Hoek, G; Shin, JW; Marino, D; Kalin, RE; Leidel, S; Cinelli, P; Schulte-Merker, S; Brandli, AW; Detmar, M,期刊：Molecular and Cellular Biology, 页码：3620-3634 , 文章类型： Article，,卷期：2010年30-14] The lymphatic vascular system maintains tissue fluid homeostasis, helps mediate afferent immune responses, and promotes cancer metastasis. To address the role microRNAs (miRNAs) play in the development and function of th... In Vivo Significance of ITK-SLP-76 Interaction in Cytokine Production [作者：Grasis, JA; Guimond, DM; Cam, NR; Herman, K; Magotti, P; Lambris, JD; Tsoukas, CD,期刊：Molecular and Cellular Biology, 页码：3596-3609 , 文章类型： Article，,卷期：2010年30-14] In vitro data have suggested that activation of the inducible T-cell kinase (ITK) requires an interaction with the adaptor protein SLP-76. One means for this interaction involves binding of the ITK SH3 domain to the poly... T-Cell Receptor Microclusters Critical for T-Cell Activation Are Formed Independently of Lipid Raft Clustering [作者：Hashimoto-Tane, A; Yokosuka, T; Ishihara, C; Sakuma, M; Kobayashi, W; Saito, T,期刊：Molecular and Cellular Biology, 页码：3421-3429 , 文章类型： Article，,卷期：2010年30-14] We studied the function of lipid rafts in generation and signaling of T-cell receptor microclusters (TCR-MCs) and central supramolecular activation clusters (cSMACs) at immunological synapse (IS). It has been suggested t... Cellular Retinol-Binding Protein Type I (CRBP-I) Regulates Adipogenesis [作者：Zizola, CF; Frey, SK; Jitngarmkusol, S; Kadereit, B; Yan, N; Vogel, S,期刊：Molecular and Cellular Biology, 页码：3412-3420 , 文章类型： Article，,卷期：2010年30-14] Adipogenesis is governed by a well-documented cascade of transcription factors. However, less is known about non-transcription factors that govern early stages of adipogenesis. Here we show that cellular retinol-binding ... Novel trans-Tail Regulation of H2B Ubiquitylation and H3K4 Methylation by the N Terminus of Histone H2A [作者：Zheng, ST; Wyrick, JJ; Reese, JC,期刊：Molecular and Cellular Biology, 页码：3635-3645 , 文章类型： Article，,卷期：2010年30-14] Chromatin is regulated by cross talk among different histone modifications, which can occur between residues within the same tail or different tails in the nucleosome. The latter is referred to as trans-tail regulation, ... KLF3 Regulates Muscle-Specific Gene Expression and Synergizes with Serum Response Factor on KLF Binding Sites [作者：Himeda, CL; Ranish, JA; Pearson, RCM; Crossley, M; Hauschka, SD,期刊：Molecular and Cellular Biology, 页码：3430-3443 , 文章类型： Article，,卷期：2010年30-14] This study identifies KLF3 as a transcriptional regulator of muscle genes and reveals a novel synergistic interaction between KLF3 and serum response factor (SRF). Using quantitative proteomics, KLF3 was identified as on... Pseudomonas Exotoxin A-Mediated Apoptosis Is Bak Dependent and Preceded by the Degradation of Mcl-1 [作者：Du, X; Youle, RJ; FitzGerald, DJ; Pastan, I,期刊：Molecular and Cellular Biology, 页码：3444-3452 , 文章类型： Article，,卷期：2010年30-14] Pseudomonas exotoxin A (PE) is a bacterial toxin that arrests protein synthesis and induces apoptosis. Here, we utilized mouse embryo fibroblasts (MEFs) deficient in Bak and Bax to determine the roles of these proteins i... FIGLA, a Basic Helix-Loop-Helix Transcription Factor, Balances Sexually Dimorphic Gene Expression in Postnatal Oocytes [作者：Hu, W; Gauthier, L; Baibakov, B; Jimenez-Movilla, M; Dean, J,期刊：Molecular and Cellular Biology, 页码：3661-3671 , 文章类型： Article，,卷期：2010年30-14] Maintenance of sex-specific germ cells requires balanced activation and repression of genetic hierarchies to ensure gender-appropriate development in mammals. Figla (factor in the germ line, alpha) encodes a germ cell-sp... Highly Specific Alternative Splicing of Transcripts Encoding BK Channels in the Chicken's Cochlea Is a Minor Determinant of the Tonotopic Gradient [作者：Miranda-Rottmann, S; Kozlov, AS; Hudspeth, AJ,期刊：Molecular and Cellular Biology, 页码：3646-3660 , 文章类型： Article，,卷期：2010年30-14] The frequency sensitivity of auditory hair cells in the inner ear varies with their longitudinal position in the sensory epithelium. Among the factors that determine the differential cellular response to sound is the res... Role of the GATA-1/FOG-1/NuRD Pathway in the Expression of Human beta-Like Globin Genes [作者：Miccio, A; Blobel, GA,期刊：Molecular and Cellular Biology, 页码：3460-3470 , 文章类型： Article，,卷期：2010年30-14] The human beta-globin genes are expressed in a developmentally controlled fashion. Studies on the molecular mechanisms underlying the stage-specific regulation of globin genes have been fueled by the clinical benefit of ... The DM Domain Transcription Factor MAB-3 Regulates Male Hypersensitivity to Oxidative Stress in Caenorhabditis elegans [作者：Inoue, H; Nishida, E,期刊：Molecular and Cellular Biology, 页码：3453-3459 , 文章类型： Article，,卷期：2010年30-14] Sex differences occur in most species and involve a variety of biological characteristics. The nematode Caenorhabditis elegans consists of two sexes, self-fertile hermaphrodites (XX) and males (XO). Males differ from her... Smad7 Regulates the Adult Neural Stem/Progenitor Cell Pool in a Transforming Growth Factor beta- and Bone Morphogenetic Protein-Independent Manner [作者：Krampert, M; Chirasani, SR; Wachs, FP; Aigner, R; Bogdahn, U; Yingling, JM; Heldin, CH; Aigner, L; Heuchel, R,期刊：Molecular and Cellular Biology, 页码：3685-3694 , 文章类型： Article，,卷期：2010年30-14] Members of the transforming growth factor beta (TGF-beta) family of proteins modulate the proliferation, differentiation, and survival of many different cell types. Neural stem and progenitor cells (NPCs) in the adult br... The POU Transcription Factor Drifter/Ventral veinless Regulates Expression of Drosophila Immune Defense Genes [作者：Junell, A; Uvell, H; Davis, MM; Edlundh-Rose, E; Antonsson, A; Pick, L; Engstrom, Y,期刊：Molecular and Cellular Biology, 页码：3672-3684 , 文章类型： Article，,卷期：2010年30-14] Innate immunity operates as a first line of defense in multicellular organisms against infections caused by different classes of microorganisms. Antimicrobial peptides (AMPs) are synthesized constitutively in barrier epi...