- An investigation of the effect of sorafenib on tumour growth and recurrence after liver cancer resection in nude mice independent of phosphorylated extracellular signal-regulated kinase levels
[作者:Wang, Z; Hu, J; Qiu, SJ; Huang, XW; Dai, Z; Tan, CJ; Zhou, J; Fan, J,期刊:Expert opinion on investigational drugs, 页码:1039-1045 , 文章类型: Article,,卷期:2011年20-8]
- Objective: The goal of this study is to investigate the effects of sorafenib on tumor growth, recurrence and metastasis after curative resection of liver cancer.Research methods: SMMC-7721 and HCCLM3 liver tumors, each w...
- Novel opioid antagonists for opioid-induced bowel dysfunction
[作者:Diego, L; Atayee, R; Helmons, P; Hsiao, G; von Gunten, CF,期刊:Expert opinion on investigational drugs, 页码:1047-1056 , 文章类型: Review,,卷期:2011年20-8]
- Introduction: Adverse effects frequently limit the therapeutic benefits of opioid analgesics. Gastrointestinal adverse effects are common, burdensome, and can compromise the quality of life. It is estimated that up to 81...
- A potential role of ruxolitinib in leukemia
[作者:Naqvi, K; Verstovsek, S; Kantarjian, H; Ravandi, F,期刊:Expert opinion on investigational drugs, 页码:1159-1166 , 文章类型: Article,,卷期:2011年20-8]
- Introduction: An increased understanding of cellular signaling pathways, like the JAK-STAT pathway, and the identification of the JAK2 V617F mutation in the classic Philadelphia chromosome-negative myeloproliferative neo...
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