- Mouse Hind Limb Transplantation: A New Composite Tissue Allotransplantation Model Using Nonsuture Supermicrosurgery
[作者:Sucher, R; Lin, CH; Zanoun, R; Atsina, KK; Weinstock, M; Pulikkotil, B; Schneeberger, S; Zheng, XX; Pratschke, J; Lee, WPA; Brandacher, G,期刊:Transplantation, 页码:1374-1380 , 文章类型: Article,,卷期:2010年90-12]
- Background. The development of microsurgical techniques has facilitated the establishment of vascularized composite tissue transplant models in small mammals. Because the mouse would be the ideal model to study various c...
- Urinary Cell Levels of mRNA for OX40, OX40L, PD-1, PD-L1, or PD-L2 and Acute Rejection of Human Renal Allografts
[作者:Afaneh, C; Muthukumar, T; Lubetzky, M; Ding, RC; Snopkowski, C; Sharma, VK; Seshan, S; Dadhania, D; Schwartz, JE; Suthanthiran, M,期刊:Transplantation, 页码:1381-1387 , 文章类型: Article,,卷期:2010年90-12]
- Background. The positive costimulatory proteins OX40 and OX40L and negative regulatory proteins programmed death (PD)-1, PD ligand 1, and PD ligand 2 have emerged as significant regulators of acute rejection in experimen...
- Islet Transplantation in Type 1 Diabetic Patients Using Calcineurin Inhibitor-Free Immunosuppressive Protocols Based on T-Cell Adhesion or Costimulation Blockade
[作者:Posselt, AM; Szot, GL; Frassetto, LA; Masharani, U; Tavakol, M; Amin, R; McElroy, J; Ramos, MD; Kerlan, RK; Fong, L; Vincenti, F; Bluestone, JA; Stock, PG,期刊:Transplantation, 页码:1595-1601 , 文章类型: Article,,卷期:2010年90-12]
- Background. The applicability of islet transplantation as treatment for type 1 diabetes is limited by long-term graft dysfunction, immunosuppressive drug toxicity, need for multiple donors, and increased risk of allosens...
- Magnetic Resonance Imaging of Pancreatic Islets Transplanted Into the Liver in Humans
[作者:Saudek, F; Jirak, D; Girman, P; Herynek, V; Dezortova, M; Kriz, J; Peregrin, J; Berkova, Z; Zacharovona, K; Hajek, M,期刊:Transplantation, 页码:1602-1606 , 文章类型: Article,,卷期:2010年90-12]
- Background. In vitro labeling of pancreatic islets by iron nanoparticles enables their detection as hypoitnense spots on serial magnetic resonance (MR) images. We report the first results of a pilot trial aiming to test ...
- Whole Blood Biomarkers of Acute Cardiac Allograft Rejection: Double-Crossing the Biopsy
[作者:Hollander, Z; Lin, D; Chen, V; Ng, R; Wilson-McManus, J; Ignaszewski, A; Freue, GC; Balshaw, R; Mui, A; McMaster, R; Keown, PA; McManus, BM,期刊:Transplantation, 页码:1388-1393 , 文章类型: Article,,卷期:2010年90-12]
- Background. Acute rejection is still a significant barrier to long-term survival of the allograft. Current acute rejection diagnostic methods are not specific enough or are invasive. There have been a number of studies t...
- CYP3A5*1 Allele: Impacts on Early Acute Rejection and Graft Function in Tacrolimus-Based Renal Transplant Recipients
[作者:Min, SI; Kim, SY; Ahn, SH; Min, SK; Kim, SH; Kim, YS; Moon, KC; Oh, JM; Kim, SJ; Ha, J,期刊:Transplantation, 页码:1394-1400 , 文章类型: Article,,卷期:2010年90-12]
- Background. Tacrolimus is a major immunosuppressant, which has a narrow therapeutic range and wide interindividual variation. The effects of genetic polymorphisms of cytochrome P450 3A (CYP3A) 5 and Adenosine triphosphat...
- Mixed Chimerism, Lymphocyte Recovery, and Evidence for Early Donor-Specific Unresponsiveness in Patients Receiving Combined Kidney and Bone Marrow Transplantation to Induce Tolerance
[作者:LoCascio, SA; Morokata, T; Chittenden, M; Preffer, FI; Dombkowski, DM; Andreola, G; Crisalli, K; Kawai, T; Saidman, SL; Spitzer, TR; Tolkoff-Rubin, N; Cosimi, AB; Sachs, DH; Sykes, M,期刊:Transplantation, 页码:1607-1615 , 文章类型: Article,,卷期:2010年90-12]
- Background. We have previously reported operational tolerance in patients receiving human leukocyte antigen-mismatched combined kidney and bone marrow transplantation (CKBMT). We now report on transient multilineage hema...
- Single-Nucleotide Polymorphisms, Acute Rejection, and Severity of Tubulitis in Kidney Transplantation, Accounting for Center-to-Center Variation
[作者:Israni, A; Leduc, R; Holmes, J; Jacobson, PA; Lamba, V; Guan, WH; Schladt, D; Chen, JB; Matas, AJ; Oetting, WS,期刊:Transplantation, 页码:1401-1408 , 文章类型: Article,,卷期:2010年90-12]
- Background. Acute rejection (AR) is associated with worse renal allograft outcomes. Therefore, this study investigated single-nucleotide polymorphisms (SNPs) to identify genetic variants associated with AR, accounting fo...
- Recombinant Phenotyping of Cytomegalovirus Sequence Variants Detected After 200 or 100 Days of Valganciclovir Prophylaxis
[作者:Chou, SW; Marousek, G; Boivin, G; Goyette, N; Farhan, M; Ives, JAL; Elston, R,期刊:Transplantation, 页码:1409-1413 , 文章类型: Article,,卷期:2010年90-12]
- Background. In a phase III controlled trial IMproved Protection Against Cytomegalovirus in Transplantation (IMPACT) comparing 200 with 100 days of valganciclovir prophylaxis in 318 cytomegalovirus D+/R - kidney transplan...
- Prolonged Prophylaxis With Valganciclovir Is Cost Effective in Reducing Posttransplant Cytomegalovirus Disease Within the United States
[作者:Blumberg, EA; Hauser, IA; Stanisic, S; Mueller, E; Berenson, K; Gahlemann, CG; Humar, A; Jardine, AG,期刊:Transplantation, 页码:1420-1426 , 文章类型: Article,,卷期:2010年90-12]
- Background. Cytomegalovirus (CMV) disease in transplant patients is known to have a substantial clinical and economic burden, and its prevention is expected to have long-term benefits. Evidence from the Improved Protecti...
- Extended Valganciclovir Prophylaxis in D+/R- Kidney Transplant Recipients is Associated With Long-Term Reduction in Cytomegalovirus Disease: Two-Year Results of the IMPACT Study
[作者:Humar, A; Limaye, AP; Blumberg, EA; Hauser, IA; Vincenti, F; Jardine, AG; Abramowicz, D; Ives, JAL; Farhan, M; Peeters, P,期刊:Transplantation, 页码:1427-1431 , 文章类型: Article,,卷期:2010年90-12]
- Background. Whether the early reduction in cytomegalovirus (CMV) disease seen at 1 year with prolongation of antiviral prophylaxis (up to 200 days) persists in the long term is unknown. Methods. This international, rando...
- Pandemic Influenza A/H1N1 Virus Infection in Solid Organ Transplant Recipients: A Multicenter Study
[作者:Smud, A; Nagel, CB; Madsen, E; Rial, MD; Barcan, LA; Gomez, AA; Martinoia, AG; Bangher, MC; Altclas, JD; Salgueira, CC; Temporiti, E; Bonvehi, PE; Enriquez, N; Efron, ED; Bibolini, JE; Lattes, R,期刊:Transplantation, 页码:1458-1462 , 文章类型: Article,,卷期:2010年90-12]
- Background. The 2009 novel influenza A/H1N1 virus pandemic did not spare solid organ transplant (SOT) recipients. We aimed to describe the behavior of pandemic influenza infection in a group of SOT recipients in Argentin...
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