- Laminar-flow immediate-overlay hepatocyte sandwich perfusion system for drug hepatotoxicity testing
[作者:Xia, L; Ng, S; Han, RB; Tuo, XY; Xiao, GF; Leo, HL; Cheng, TM; Yu, HR,期刊:BIOMATERIALS, 页码:5927-5936 , 文章类型: Article,,卷期:2009年30-30]
- Drug hepatotoxicity testing requires in vitro hepatocyte culture to maintain the long-term and stable liver specific functions. We developed a drug testing platform based on laminar-flow immediate-overlay hepatocyte sand...
- On the nature of biomaterials
[作者:Williams, DF,期刊:BIOMATERIALS, 页码:5897-5909 , 文章类型: Article,,卷期:2009年30-30]
- The situations in which biomaterials are currently used are vastly different to those of just a decade ago. Although implantable medical devices are still immensely important, medical technologies now encompass a range o...
- Bioengineering of a functional sheet of islet cells for the treatment of diabetes mellitus
[作者:Shimizu, H; Ohashi, K; Utoh, R; Ise, K; Gotoh, M; Yamato, M; Okano, T,期刊:BIOMATERIALS, 页码:5943-5949 , 文章类型: Article,,卷期:2009年30-30]
- The present study was designed to establish a novel tissue engineering approach for diabetes mellitus (DM) by fabricating a tissue sheet composed of pancreatic islet cells for in vivo transplantation. Pancreatic islet ce...
- The growth and differentiation of mesenchymal stem and progenitor cells cultured on aligned collagen matrices
[作者:Lanfer, B; Seib, FP; Freudenberg, U; Stamov, D; Bley, T; Bornhauser, M; Werner, C,期刊:BIOMATERIALS, 页码:5950-5958 , 文章类型: Article,,卷期:2009年30-30]
- Cell-matrix interactions are paramount for the successful repair and regeneration of damaged and diseased tissue. Since many tissues have an anisotropic architecture, it has been proposed that aligned extracellular matri...
- Enzymatically fabricated and degradable microcapsules for production of multicellular spheroids with well-defined diameters of less than 150 mu m
[作者:Sakai, S; Ito, S; Ogushi, Y; Hashimoto, I; Hosoda, N; Sawae, Y; Kawakami, K,期刊:BIOMATERIALS, 页码:5937-5942 , 文章类型: Article,,卷期:2009年30-30]
- Microcapsules with a single, spherical hollow core less than 150 mu m in diameter were developed to obtain multicellular spheroids with well-defined sizes of less than 150 mu m in diameter. An aqueous solution of phenoli...
- Antibiofilm activity of nanosized magnesium fluoride
[作者:Lellouche, J; Kahana, E; Elias, S; Gedanken, A; Banin, E,期刊:BIOMATERIALS, 页码:5969-5978 , 文章类型: Article,,卷期:2009年30-30]
- The ability of bacteria to develop antibiotic resistance and colonize abiotic surfaces by forming biofilms Is a major cause of medical implant-associated infections and results in prolonged hospitalization periods and pa...
- The disruption of bacterial membrane integrity through ROS generation induced by nanohybrids of silver and clay
[作者:Su, HL; Chou, CC; Hung, DJ; Lin, SH; Pao, IC; Lin, JH; Huang, FL; Dong, RX; Lin, JJ,期刊:BIOMATERIALS, 页码:5979-5987 , 文章类型: Article,,卷期:2009年30-30]
- Nanohybrids, synthesized via silver nitrate reduction in the presence of silicate clay, exhibit a high potency against bacterial growth. The plate-like clay, due to its anionic surface charges and a large surface area, s...
- Rapid three-dimensional quantification of VEGF-induced scaffold neovascularisation by microcomputed tomography
[作者:Schmidt, C; Bezuidenhout, D; Beck, M; Van der Merwe, E; Zilla, P; Davies, N,期刊:BIOMATERIALS, 页码:5959-5968 , 文章类型: Article,,卷期:2009年30-30]
- Microcomputed tomography (micro-CT) is increasingly being used to analyze the three-dimensional structure and architecture of microvascular networks. Therefore we have evaluated a micro-CT analysis of VEGF-induced vessel...
- A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer
[作者:Xiao, K; Luo, JT; Fowler, WL; Li, YP; Lee, JS; Xing, L; Cheng, RH; Wang, L; Lam, KS,期刊:BIOMATERIALS, 页码:6006-6016 , 文章类型: Article,,卷期:2009年30-30]
- Paclitaxel (PTX) is one of the most effective chemotherapeutic drugs for the treatment of a variety of cancers. However, it is associated with serious side effects caused by PTX itself and the Cremophor EL emulsifier. In...
- Cholesterol-mediated anchoring of enzyme-loaded liposomes within disulfide-stabilized polymer carrier capsules
[作者:Chandrawati, R; Stadler, B; Postma, A; Connal, LA; Chong, SF; Zelikin, AN; Caruso, F,期刊:BIOMATERIALS, 页码:5988-5998 , 文章类型: Article,,卷期:2009年30-30]
- Polymer capsules containing multiple liposomes, termed capsosomes, are a promising new concept toward the design of artificial cells. Herein, we report on the fundamental aspects underpinning the assembly of capsosomes. ...
- Synthesis, characterization, and preliminary assessment of anti-Flt1 peptide-hyaluronate conjugate for the treatment of corneal neovascularization
[作者:Oh, EJ; Park, K; Choi, JS; Joo, CK; Hahn, SK,期刊:BIOMATERIALS, 页码:6026-6034 , 文章类型: Article,,卷期:2009年30-30]
- Anti-Flt1 peptide of GNQWFI has been reported to inhibit vascular endothelial growth factor receptor 1 (VEGFR1) - mediated endothelial cell migration and tube formation. In this work, a protocol to synthesize anti-Flt1 p...
- The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes
[作者:Yang, DR; Pornpattananangkul, D; Nakatsuji, T; Chan, M; Carson, D; Huang, CM; Zhang, LF,期刊:BIOMATERIALS, 页码:6035-6040 , 文章类型: Article,,卷期:2009年30-30]
- This study evaluated the antimicrobial activity of lauric acid (LA) and its liposomal derivatives against Propionibacterium acnes (P. acnes), the bacterium that promotes inflammatory acne. First, the antimicrobial study ...
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