- Identification and expression analysis of a novel transcript of the human PRMT2 gene resulted from alternative polyadenylation in breast cancer
[作者:Zhong, J; Cao, RX; Hong, T; Yang, J; Zu, XY; Xiao, XH; Liu, JH; Wen, GB,期刊:Gene, 页码:1-9 , 文章类型: Article,,卷期:2011年487-1]
- The arginine N-methyltransferase 2 protein (PRMT2, also known as HRMT1L1) is thought to act as a coactivator of ER alpha. The present results show the occurrence of a novel transcript by alternative polyadenylation in th...
- Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population
[作者:Cardenas, CLL; Renault, N; Farce, A; Cauffiez, C; Allorge, D; Lo-Guidice, JM; Lhermitte, M; Chavatte, P; Broly, F; Chevalier, D,期刊:Gene, 页码:10-20 , 文章类型: Article,,卷期:2011年487-1]
- The CYP4A subfamily is known to omega-hydroxylate the endogenous arachidonic acid into 20-hydroxyeicosatetranoic acid, which has renovascular and tubular functions. The aim of this work was to report a comprehensive inve...
- RANTES gene mRNA expression and its-403 G/A promoter polymorphism in coronary artery disease
[作者:Tavakkoly-Bazzaz, J; Amiri, P; Tajmir-Riahi, M; Javidi, D; Khojasteh-Fard, M; Taheri, Z; Tabrizi, A; Keramatipour, M; Amoli, MM,期刊:Gene, 页码:103-106 , 文章类型: Article,,卷期:2011年487-1]
- Objective: Increased RANTES expression has been described to have a role in atherosclerosis plaque formation. Functional polymorphisms within RANTES promoter region have shown association with increased risk of coronary ...
- Pentoxifylline administration changes protein expression profile of coronary artery disease patients
[作者:Shamsara, J; Behravan, J; Falsoleiman, H; Mohammadpour, AH; Rendeirs, J; Ramezani, M,期刊:Gene, 页码:107-111 , 文章类型: Article,,卷期:2011年487-1]
- Increased level of inflammatory mediators plays a central role in the features of coronary artery diseases. As pentoxifylline could suppress the inflammatory process and has shown some promising beneficial effects in inf...
- Comparative genomic analysis of dinucleotide repeats in Tritryps
[作者:Duhagon, MA; Smircich, P; Forteza, D; Naya, H; Williams, N; Garat, B,期刊:Gene, 页码:29-37 , 文章类型: Article,,卷期:2011年487-1]
- The protozoans Trypanosoma cruzi, Trypanosoma brucei and Leishmania major (Tritryps), are evolutionarily ancient eukaryotes which cause worldwide human parasitosis. They present unique biological features. Indeed, canoni...
- Molecular characterization and tissue-specific expression of the acetyl-CoA carboxylase alpha gene from Grass carp, Ctenopharyngodon idella
[作者:Cheng, HL; Ji, NJ; Peng, YX; Shen, X; Xu, JH; Dong, ZG; Wu, CC,期刊:Gene, 页码:46-51 , 文章类型: Article,,卷期:2011年487-1]
- Acetyl-CoA carboxylase alpha (ACC1), the major regulatory enzyme of fatty acid biosynthesis, catalyzes the conversion of acetyl-CoA to malonyl-CoA. The full-length cDNA coding ACC1 isoform was cloned from liver of grass ...
- The polypyrimidine/polypurine motif in the mouse mu opioid receptor gene promoter is a supercoiling-regulatory element
[作者:Choe, CY; Kim, H; Dong, JP; van Wijnen, AJ; Law, PY; Loh, HH,期刊:Gene, 页码:52-61 , 文章类型: Article,,卷期:2011年487-1]
- The mu opioid receptor (MOR) is the principle molecular target of opioid analgesics. The polypyrimidine/polypurine (PPy/u) motif enhances the activity of the MOR gene promoter by adopting a non-B DNA conformation. Here, ...
- A simple and effective SuperBuffer for DNA agarose electrophoresis
[作者:Zhang, JH; Wang, F; Wang, TY,期刊:Gene, 页码:72-74 , 文章类型: Article,,卷期:2011年487-1]
- In the paper, we describe a unique effective electrophoresis buffer for DNA agarose electrophoresis, called SuperBuffer. Using this buffer, electrophoresis could be performed within 10 min at voltages as high as 25 V/cm....
- A simple and rapid technique for the authentication of the ginseng cultivar, Yunpoong, using an SNP marker in a large sample of ginseng leaves
[作者:Sun, H; Wang, HT; Kwon, WS; Kim, YJ; In, JG; Yang, DC,期刊:Gene, 页码:75-79 , 文章类型: Article,,卷期:2011年487-1]
- Yunpoong is an important Korean ginseng (Panax ginseng C. A. Meyer) cultivar, but no molecular marker has been available to identify Yunpoong from other cultivars. In this study, we developed a single nucleotide polymorp...
- Relation between 3435C > T multidrug resistance 1 gene polymorphism with high dose methylprednisolone treatment of childhood acute idiopathic thrombocytopenic purpura
[作者:Akin, M; Turgut, S; Ayada, C; Polat, Y; Balci, YI; Erdogan, F,期刊:Gene, 页码:80-83 , 文章类型: Article,,卷期:2011年487-1]
- The current study was conducted to assess 3435C>T multidrug resistance 1 gene polymorphism and the efficacy of high dose methylprednisolone (HDMP) in childhood acute idiopathic thrombocytopenic purpura patients. Methods:...
- Allele frequencies of 6 autosomal STR loci in the Xibo nationality with phylogenetic structure among Chinese populations
[作者:Liu, J; Li, SY; Yin, JY; Zhang, W; Gao, B; Guo, L; Qi, R,期刊:Gene, 页码:84-87 , 文章类型: Article,,卷期:2011年487-1]
- In the present study, we investigated the genetic polymorphisms of 6 autosomal STR loci Hum-CSF1PO, D13S317, D5S818, D16S539, TH01, and TPOX in the Xibo population of Liaoning, northeastern China as well as its genetic r...
- Serum paraoxonase-1 (PON1) activities (PONase/AREase) and polymorphisms in patients with type 2 diabetes mellitus in a North-West Indian population
[作者:Gupta, N; Binukumar, BK; Singh, S; Sunkaria, A; Kandimalla, R; Bhansali, A; Gill, KD,期刊:Gene, 页码:88-95 , 文章类型: Article,,卷期:2011年487-1]
- Objective: Paraoxonase-1 (PON1), an HDL-C associated enzyme, protects lipoproteins from oxidation. There is evidence that PON1 enzyme activity is reduced in the patients with type 2 diabetes mellitus (T2DM). North-West I...
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