- An Alternative Kaposi's Sarcoma-Associated Herpesvirus Replication Program Triggered by Host Cell Apoptosis
[作者:Prasad, A; Lu, M; Lukac, DM; Zeichner, SL,期刊:Journal of virology, 页码:4404-4419 , 文章类型: Article,,卷期:2012年86-8]
- Kaposi's sarcoma-associated herpesvirus (KSHV) is linked to several neoplastic diseases: Kaposi's sarcoma, primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD). KSHV replicates actively, via a cont...
- The UL36 Tegument Protein of Herpes Simplex Virus 1 Has a Composite Binding Site at the Capsid Vertices
[作者:Cardone, G; Newcomb, WW; Cheng, NQ; Wingfield, PT; Trus, BL; Brown, JC; Steven, AC,期刊:Journal of virology, 页码:4058-4064 , 文章类型: Article,,卷期:2012年86-8]
- Herpesviruses have an icosahedral nucleocapsid surrounded by an amorphous tegument and a lipoprotein envelope. The tegument comprises at least 20 proteins destined for delivery into the host cell. As the tegument does no...
- Effect of gamma 34.5 Deletions on Oncolytic Herpes Simplex Virus Activity in Brain Tumors
[作者:Kanai, R; Zaupa, C; Sgubin, D; Antoszczyk, SJ; Martuza, RL; Wakimoto, H; Rabkin, SD,期刊:Journal of virology, 页码:4420-4431 , 文章类型: Article,,卷期:2012年86-8]
- The ICP34.5 protein of herpes simplex virus (HSV) is involved in many aspects of viral pathogenesis; promoting neurovirulence, inhibiting interferon-induced shutoff of protein synthesis, interacting with PCNA and TBK1, i...
- Nonstructural Proteins 7 and 8 of Feline Coronavirus Form a 2:1 Heterotrimer That Exhibits Primer-Independent RNA Polymerase Activity
[作者:Xiao, YB; Ma, QJ; Restle, T; Shang, WF; Svergun, DI; Ponnusamy, R; Sczakiel, G; Hilgenfeld, R,期刊:Journal of virology, 页码:4444-4454 , 文章类型: Article,,卷期:2012年86-8]
- Nonstructural proteins 7 and 8 of severe acute respiratory syndrome coronavirus (SARS-CoV) have previously been shown by X-ray crystallography to form an 8:8 hexadecamer. In addition, it has been demonstrated that N-term...
- Superior Induction of T Cell Responses to Conserved HIV-1 Regions by Electroporated Alphavirus Replicon DNA Compared to That with Conventional Plasmid DNA Vaccine
[作者:Knudsen, ML; Mbewe-Mvula, A; Rosario, M; Johansson, DX; Kakoulidou, M; Bridgeman, A; Reyes-Sandoval, A; Nicosia, A; Ljungberg, K; Hanke, T; Liljestrom, P,期刊:Journal of virology, 页码:4082-4090 , 文章类型: Article,,卷期:2012年86-8]
- Vaccination using "naked" DNA is a highly attractive strategy for induction of pathogen-specific immune responses; however, it has been only weakly immunogenic in humans. Previously, we constructed DNA-launched Semliki F...
- The Human Cytomegalovirus-Specific UL1 Gene Encodes a Late-Phase Glycoprotein Incorporated in the Virion Envelope
[作者:Shikhagaie, M; Merce-Maldonado, E; Isern, E; Muntasell, A; Alba, MM; Lopez-Botet, M; Hengel, H; Angulo, A,期刊:Journal of virology, 页码:4091-4101 , 文章类型: Article,,卷期:2012年86-8]
- We have investigated the previously uncharacterized human cytomegalovirus (HCMV) UL1 open reading frame (ORF), a member of the rapidly evolving HCMV RL11 family. UL1 is HCMV specific; the absence of UL1 in chimpanzee cyt...
- Residue Y161 of Influenza Virus Hemagglutinin Is Involved in Viral Recognition of Sialylated Complexes from Different Hosts
[作者:Wang, MX; Tscherne, DM; McCullough, C; Caffrey, M; Garcia-Sastre, A; Rong, LJ,期刊:Journal of virology, 页码:4455-4462 , 文章类型: Article,,卷期:2012年86-8]
- Influenza A virus glycoprotein hemagglutinin (HA) binds to host cell surface sialic acid (SA)-terminated sugars in glycoproteins to initiate viral entry. It is thought that avian influenza viruses preferentially bind to ...
- Herpes B Virus Utilizes Human Nectin-1 but Not HVEM or PILR alpha for Cell-Cell Fusion and Virus Entry
[作者:Fan, Q; Amen, M; Harden, M; Severini, A; Griffiths, A; Longnecker, R,期刊:Journal of virology, 页码:4468-4476 , 文章类型: Article,,卷期:2012年86-8]
- To investigate the requirements of herpesvirus entry and fusion, the four homologous glycoproteins necessary for herpes simplex virus (HSV) fusion were cloned from herpes B virus (BV) (or macacine herpesvirus 1, previous...
- Restoration of TLR3-Activated Myeloid Dendritic Cell Activity Leads to Improved Natural Killer Cell Function in Chronic Hepatitis B Virus Infection
[作者:Tjwa, ETTL; van Oord, GW; Biesta, PJ; Boonstra, A; Janssen, HLA; Woltman, AM,期刊:Journal of virology, 页码:4102-4109 , 文章类型: Article,,卷期:2012年86-8]
- There is increasing evidence that the function of NK cells in patients with chronic hepatitis B (CHB) infection is impaired. The underlying mechanism for the impaired NK cell function is still unknown. Since myeloid dend...
- Bovine Type III Interferon Significantly Delays and Reduces the Severity of Foot-and-Mouth Disease in Cattle
[作者:Perez-Martin, E; Weiss, M; Segundo, FDS; Pacheco, JM; Arzt, J; Grubman, MJ; de los Santos, T,期刊:Journal of virology, 页码:4477-4487 , 文章类型: Article,,卷期:2012年86-8]
- Interferons (IFNs) are the first line of defense against viral infections. Although type I and II IFNs have proven effective to inhibit foot-and-mouth disease virus (FMDV) replication in swine, a similar approach had onl...
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