- Generation of an HIV-1-Resistant Immune System with CD34(+) Hematopoietic Stem Cells Transduced with a Triple-Combination Anti-HIV Lentiviral Vector
[作者:Walker, JE; Chen, RX; McGee, J; Nacey, C; Pollard, RB; Abedi, M; Bauer, G; Nolta, JA; Anderson, JS,期刊:Journal of virology, 页码:5719-5729 , 文章类型: Article,,卷期:2012年86-10]
- HIV gene therapy has the potential to offer an alternative to the use of current small-molecule antiretroviral drugs as a treatment strategy for HIV-infected individuals. Therapies designed to administer HIV-resistant st...
- The Second Receptor Binding Site of the Globular Head of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Activates the Stalk of Multiple Paramyxovirus Receptor Binding Proteins To Trigger Fusion
[作者:Porotto, M; Salah, Z; DeVito, I; Talekar, A; Palmer, SG; Xu, R; Wilson, IA; Moscona, A,期刊:Journal of virology, 页码:5730-5741 , 文章类型: Article,,卷期:2012年86-10]
- The hemagglutinin-neuraminidase (HN) protein of paramyxoviruses carries out three distinct activities contributing to the ability of HN to promote viral fusion and entry: receptor binding, receptor cleavage (neuraminidas...
- Retroviral Cyclin Enhances Cyclin-Dependent Kinase-8 Activity
[作者:Rovnak, J; Brewster, CD; Quackenbush, SL,期刊:Journal of virology, 页码:5742-5751 , 文章类型: Article,,卷期:2012年86-10]
- Alterations in the functional levels of cyclin-dependent kinase-8 (CDK8) or its partner, cyclin C, have been clearly associated with cancers, including colon cancer, melanoma, and osteosarcoma. Walleye dermal sarcoma vir...
- Cold-Adapted Pandemic 2009 H1N1 Influenza Virus Live Vaccine Elicits Cross-Reactive Immune Responses against Seasonal and H5 Influenza A Viruses
[作者:Jang, YH; Byun, YH; Lee, YJ; Lee, YH; Lee, KH; Seong, BL,期刊:Journal of virology, 页码:5953-5958 , 文章类型: Article,,卷期:2012年86-10]
- The rapid transmission of the pandemic 2009 H1N1 influenza virus (pH1N1) among humans has raised the concern of a potential emergence of reassortment between pH1N1 and highly pathogenic influenza strains, especially the ...
- Structure of the Fab-Labeled "Breathing" State of Native Poliovirus
[作者:Lin, J; Lee, LY; Roivainen, M; Filman, DJ; Hogle, JM; Belnap, DM,期刊:Journal of virology, 页码:5959-5962 , 文章类型: Article,,卷期:2012年86-10]
- At 37 degrees C, the structure of poliovirus is dynamic, and internal polypeptides VP4 and N terminus of VP1 (residues 1 to 53) externalize reversibly. An Fab fragment of a monospecific antibody, which binds to residues ...
- Complete Genome Sequence of the Rearranged Porcine Circovirus Type 2
[作者:Wen, LB; He, KW; Ni, YX; Zhang, XH; Li, B; Wang, XM; Guo, RL; Yu, ZY; Mao, AH; Zhou, JM; Lv, LX; Jiang, JY,期刊:Journal of virology, 页码:5963-5963 , 文章类型: Article,,卷期:2012年86-10]
- We first report here the genome sequences of 4 rearranged porcine circovirus type 2 strains, JSTZ, ZJQDH1, ZJQDH2, and JSHM, isolated from porcine sera in China. The complete circular genomes of these isolates are 578, 4...
- Complete Genome Sequences of a Korean Virulent Porcine Epidemic Diarrhea Virus and Its Attenuated Counterpart
[作者:Park, SJ; Kim, HK; Song, DS; An, DJ; Park, BK,期刊:Journal of virology, 页码:5964-5964 , 文章类型: Article,,卷期:2012年86-10]
- A virulent porcine epidemic diarrhea virus (PEDV) strain, DR13, was obtained from suckling pigs suspected of having porcine epidemic diarrhea in 1999 in Korea, and its attenuated counterpart was derived from virulent str...
- Complete Genomic Sequence of Chinese Virulent Duck Enteritis Virus
[作者:Wu, Y; Cheng, AC; Wang, MS; Yang, Q; Zhu, DK; Jia, RY; Chen, S; Zhou, Y; Wang, XY; Chen, XY,期刊:Journal of virology, 页码:5965-5965 , 文章类型: Article,,卷期:2012年86-10]
- The Chinese virulent (CHv) strain of duck enteritis virus (DEV) has a genome of approximately 162,175 nucleotides with a GC content of 44.89%. Here we report the complete genomic sequence and annotation of DEV CHv, which...
- Identification of Host-Chromosome Binding Sites and Candidate Gene Targets for Kaposi's Sarcoma-Associated Herpesvirus LANA
[作者:Lu, F; Tsai, K; Chen, HS; Wikramasinghe, P; Davuluri, RV; Showe, L; Domsic, J; Marmorstein, R; Lieberman, PM,期刊:Journal of virology, 页码:5752-5762 , 文章类型: Article,,卷期:2012年86-10]
- LANA is essential for tethering the Kaposi's sarcoma-associated herpesvirus (KSHV) genome to metaphase chromosomes and for modulating host-cell gene expression, but the binding sites in the host-chromosome remain unknown...
- Targeting of Dicer-2 and RNA by a Viral RNA Silencing Suppressor in Drosophila Cells
[作者:Qi, N; Zhang, L; Qiu, Y; Wang, ZW; Si, J; Liu, YX; Xiang, X; Xie, JZ; Qin, CF; Zhou, X; Hu, YY,期刊:Journal of virology, 页码:5763-5773 , 文章类型: Article,,卷期:2012年86-10]
- RNA interference (RNAi) is a eukaryotic gene-silencing mechanism that functions in antiviral immunity in diverse organisms. To combat RNAi-mediated immunity, viruses encode viral suppressors of RNA silencing (VSRs) that ...
- Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes
[作者:Hai, R; Krammer, F; Tan, GS; Pica, N; Eggink, D; Maamary, J; Margine, I; Albrecht, RA; Palese, P,期刊:Journal of virology, 页码:5774-5781 , 文章类型: Article,,卷期:2012年86-10]
- The influenza virus hemagglutinin molecule possesses a globular head domain that mediates receptor binding and a stalk domain at the membrane-proximal region. We generated functional influenza viruses expressing chimeric...
- Attenuated Influenza Virus Construct with Enhanced Hemagglutinin Protein Expression
[作者:Maamary, J; Pica, N; Belicha-Villanueva, A; Chou, YY; Krammer, F; Gao, QS; Garcia-Sastre, A; Palese, P,期刊:Journal of virology, 页码:5782-5790 , 文章类型: Article,,卷期:2012年86-10]
- Influenza A viruses encoding an altered viral NS1 protein have emerged as promising live attenuated vaccine platforms. A carboxy-terminal truncation in the NS1 protein compromises its interferon antagonism activity, maki...
- Complete Genome Sequence of Canine Papillomavirus Type 9
[作者:Yuan, H; Luff, J; Zhou, D; Wang, JG; Affolter, V; Moore, P; Schlegel, R,期刊:Journal of virology, 页码:5966-5966 , 文章类型: Article,,卷期:2012年86-10]
- Papillomaviruses are nonenveloped, double-stranded DNA viruses that are associated with both benign and malignant tumors in animals and humans. We report the complete genome sequence of canine papillomavirus type 9 isola...
- The Genome Sequence of Bluetongue Virus Type 2 from India: Evidence for Reassortment between Eastern and Western Topotype Field Strains
[作者:Maan, NS; Maan, S; Nomikou, K; Guimera, M; Pullinger, G; Singh, KP; Belaganahalli, MN; Mertens, PPC,期刊:Journal of virology, 页码:5967-5968 , 文章类型: Article,,卷期:2012年86-10]
- Bluetongue virus type 2, isolated in India in 1982 (IND1982/01), was obtained from the Orbivirus Reference Collection at IAH Pirbright (http://www.reoviridae.org/dsRNA_virus_proteins/ReoID/btv-2.htm#IND1982/01). Full gen...
- Complete Genome Sequences of Newcastle Disease Virus Strains Circulating in Chicken Populations of Indonesia
[作者:Xiao, S; Paldurai, A; Nayak, B; Samuel, A; Bharoto, EE; Prajitno, TY; Collins, PL; Samal, SK,期刊:Journal of virology, 页码:5969-5970 , 文章类型: Article,,卷期:2012年86-10]
- Eight highly virulent Newcastle disease virus (NDV) strains were isolated from vaccinated commercial chickens in Indonesia during outbreaks in 2009 and 2010. The complete genome sequences of two NDV strains and the seque...
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