- Evolutionary Dynamics of Local Pandemic H1N1/2009 Influenza Virus Lineages Revealed by Whole-Genome Analysis
[作者:Baillie, GJ; Galiano, M; Agapow, PM; Myers, R; Chiam, R; Gall, A; Palser, AL; Watson, SJ; Hedge, J; Underwood, A; Platt, S; McLean, E; Pebody, RG; Rambaut, A; Green, J; Daniels, R; Pybus, OG; Kellam, P; Zambon, M,期刊:Journal of virology, 页码:11-18 , 文章类型: Article,,卷期:2012年86-1]
- Virus gene sequencing and phylogenetics can be used to study the epidemiological dynamics of rapidly evolving viruses. With complete genome data, it becomes possible to identify and trace individual transmission chains o...
- Latent HIV-1 Infection of Resting CD4(+) T Cells in the Humanized Rag2(-/-) gamma(-/-)(c) Mouse
[作者:Choudhary, SK; Archin, NM; Cheema, M; Dahl, NP; Garcia, JV; Margolis, DM,期刊:Journal of virology, 页码:114-120 , 文章类型: Article,,卷期:2012年86-1]
- Persistent human immunodeficiency virus type 1 (HIV-1) infection of resting CD4(+) T cells, unaffected by antiretroviral therapy (ART), provides a long-lived reservoir of HIV infection. Therapies that target this viral r...
- Amino Acid Changes in Hemagglutinin Contribute to the Replication of Oseltamivir-Resistant H1N1 Influenza Viruses
[作者:Ginting, TE; Shinya, K; Kyan, Y; Makino, A; Matsumoto, N; Kaneda, S; Kawaoka, Y,期刊:Journal of virology, 页码:121-127 , 文章类型: Article,,卷期:2012年86-1]
- Oseltamivir-resistant H1N1 influenza viruses emerged in 2007 to 2008 and have subsequently circulated widely. However, prior to 2007 to 2008, viruses possessing the neuraminidase (NA) H274Y mutation, which confers oselta...
- Engineering, Expression, Purification, and Characterization of Stable Clade A/B Recombinant Soluble Heterotrimeric gp140 Proteins
[作者:Sellhorn, G; Kraft, Z; Caldwell, Z; Ellingson, K; Mineart, C; Seaman, MS; Montefiori, DC; Lagerquist, E; Stamatatos, L,期刊:Journal of virology, 页码:128-142 , 文章类型: Article,,卷期:2012年86-1]
- The envelope glycoprotein (Env) of human immunodeficiency virus type 1 (HIV-1) is composed of two noncovalently associated subunits: an extracellular subunit (gp120) and a transmembrane subunit (gp41). The functional uni...
- Requirements for Mouse Mammary Tumor Virus Rem Signal Peptide Processing and Function
[作者:Byun, H; Halani, N; Gou, YQ; Nash, AK; Lozano, MM; Dudley, JP,期刊:Journal of virology, 页码:214-225 , 文章类型: Article,,卷期:2012年86-1]
- Mouse mammary tumor virus (MMTV) encodes a Rev-like protein, Rem, which is involved in the nuclear export and expression of viral RNA. Previous data have shown that all Rev-like functions are localized to the 98-amino-ac...
- Down-Modulation of CD8 alpha beta Is a Fundamental Activity of Primate Lentiviral Nef Proteins
[作者:Heigele, A; Schindler, M; Gnanadurai, CW; Leonard, JA; Collins, KL; Kirchhoff, F,期刊:Journal of virology, 页码:36-48 , 文章类型: Article,,卷期:2012年86-1]
- It is well established that the Nef proteins of human and simian immunodeficiency viruses (HIV and SIV) modulate major histocompatibility complex class I (MHC-I) cell surface expression to protect infected cells against ...
- Cathepsin Cleavage Potentiates the Ebola Virus Glycoprotein To Undergo a Subsequent Fusion-Relevant Conformational Change
[作者:Brecher, M; Schornberg, KL; Delos, SE; Fusco, ML; Saphire, EO; White, JM,期刊:Journal of virology, 页码:364-372 , 文章类型: Article,,卷期:2012年86-1]
- Cellular entry of Ebola virus (EBOV), a deadly hemorrhagic fever virus, is mediated by the viral glycoprotein (GP). The receptor-binding subunit of GP must be cleaved (by endosomal cathepsins) in order for entry and infe...
- Apparent Expression of Varicella-Zoster Virus Proteins in Latency Resulting from Reactivity of Murine and Rabbit Antibodies with Human Blood Group A Determinants in Sensory Neurons
[作者:Zerboni, L; Sobel, RA; Lai, M; Triglia, R; Steain, M; Abendroth, A; Arvina, A,期刊:Journal of virology, 页码:578-583 , 文章类型: Article,,卷期:2012年86-1]
- Analyses of varicella-zoster virus (VZV) protein expression during latency have been discordant, with rare to many positive neurons detected. We show that ascites-derived murine and rabbit antibodies specific for VZV pro...
- Length Variations in the NA Stalk of an H7N1 Influenza Virus Have Opposite Effects on Viral Excretion in Chickens and Ducks
[作者:Hoffmann, TW; Munier, S; Larcher, T; Soubieux, D; Ledevin, M; Esnault, E; Tourdes, A; Croville, G; Guerin, JL; Quere, P; Volmer, R; Naffakh, N; Marc, D,期刊:Journal of virology, 页码:584-588 , 文章类型: Article,,卷期:2012年86-1]
- A deletion of similar to 20 amino acids in the stalk of neuraminidase is frequently observed upon transmission of influenza A viruses from waterfowl to domestic poultry. A pair of recombinant H7N1 viruses bearing either ...
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