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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共22条记录   June bloom in Maratea [作者：Parcy, F; Lohmann, JU,期刊：Development, 页码：4335-4340 , 文章类型： Editorial Material，,卷期：2011年138-20] The International Workshop on Molecular Mechanisms Controlling Flower Development took place in the secluded southern Italian village of Maratea in June 2011. This meeting, which takes place biennially, gathers researche... Maintaining embryonic stem cell pluripotency with Wnt signaling [作者：Sokol, SY,期刊：Development, 页码：4341-4350 , 文章类型： Review，,卷期：2011年138-20] Wnt signaling pathways control lineage specification in vertebrate embryos and regulate pluripotency in embryonic stem (ES) cells, but how the balance between progenitor self-renewal and differentiation is achieved durin... ApoE is required for maintenance of the dentate gyrus neural progenitor pool [作者：Yang, CP; Gilley, JA; Zhang, G; Kernie, SG,期刊：Development, 页码：4351-4362 , 文章类型： Article，,卷期：2011年138-20] Many genes regulating adult neurogenesis have been identified and are known to play similar roles during early neuronal development. We recently identified apolipoprotein E (ApoE) as a gene the expression of which is ess... Temporally controlled modulation of FGF/ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells [作者：Jaeger, I; Arber, C; Risner-Janiczek, JR; Kuechler, J; Pritzsche, D; Chen, IC; Naveenan, T; Ungless, MA; Li, M,期刊：Development, 页码：4363-4374 , 文章类型： Article，,卷期：2011年138-20] Effective induction of midbrain-specific dopamine (mDA) neurons from stem cells is fundamental for realizing their potential in biomedical applications relevant to Parkinson's disease. During early development, the Otx2-... Cell shape and Wnt signaling redundantly control the division axis of C. elegans epithelial stem cells [作者：Wildwater, M; Sander, N; de Vreede, G; van den Heuvel, S,期刊：Development, 页码：4375-4385 , 文章类型： Article，,卷期：2011年138-20] Tissue-specific stem cells combine proliferative and asymmetric divisions to balance self-renewal with differentiation. Tight regulation of the orientation and plane of cell division is crucial in this process. Here, we ... A regulatory program for excretory system regeneration in planarians [作者：Scimone, ML; Srivastava, M; Bell, GW; Reddien, PW,期刊：Development, 页码：4387-4398 , 文章类型： Article，,卷期：2011年138-20] Planarians can regenerate any missing body part, requiring mechanisms for the production of organ systems in the adult, including their prominent tubule-based filtration excretory system called protonephridia. Here, we i... Prdm1a and miR-499 act sequentially to restrict Sox6 activity to the fast-twitch muscle lineage in the zebrafish embryo [作者：Wang, XG; Ono, Y; Tan, SC; Chai, RJ; Parkin, C; Ingham, PW,期刊：Development, 页码：4399-4404 , 文章类型： Article，,卷期：2011年138-20] Sox6 has been proposed to play a conserved role in vertebrate skeletal muscle fibre type specification. In zebrafish, sox6 transcription is repressed in slow-twitch progenitors by the Prdm1a transcription factor. Here we... Two additional midline barriers function with midline lefty1 expression to maintain asymmetric Nodal signaling during left-right axis specification in zebrafish [作者：Lenhart, KF; Lin, SY; Titus, TA; Postlethwait, JH; Burdine, RD,期刊：Development, 页码：4405-4410 , 文章类型： Article，,卷期：2011年138-20] Left-right (L/R) patterning is crucial for the proper development of all vertebrates and requires asymmetric expression of nodal in the lateral plate mesoderm (LPM). The mechanisms governing asymmetric initiation of noda... Dynamic localization of C. elegans TPR-GoLoco proteins mediates mitotic spindle orientation by extrinsic signaling [作者：Werts, AD; Roh-Johnson, M; Goldstein, B,期刊：Development, 页码：4411-4422 , 文章类型： Article，,卷期：2011年138-20] Cell divisions are sometimes oriented by extrinsic signals, by mechanisms that are poorly understood. Proteins containing TPR and GoLoco-domains (C. elegans GPR-1/2, Drosophila Pins, vertebrate LGN and AGS3) are candidat... Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis [作者：Grosse, AS; Pressprich, MF; Curley, LB; Hamilton, KL; Margolis, B; Hildebrand, JD; Gumucio, DL,期刊：Development, 页码：4423-4432 , 文章类型： Article，,卷期：2011年138-20] The cellular mechanisms that drive growth and remodeling of the early intestinal epithelium are poorly understood. Current dogma suggests that the murine fetal intestinal epithelium is stratified, that villi are formed b... UNC-6/netrin and its receptors UNC-5 and UNC-40/DCC modulate growth cone protrusion in vivo in C. elegans [作者：Norris, AD; Lundquist, EA,期刊：Development, 页码：4433-4442 , 文章类型： Article，,卷期：2011年138-20] The UNC-6/netrin guidance cue functions in axon guidance in vertebrates and invertebrates, mediating attraction via UNC-40/DCC family receptors and repulsion via by UNC-5 family receptors. The growth cone reads guidance ... Individual axons regulate the myelinating potential of single oligodendrocytes in vivo [作者：Almeida, RG; Czopka, T; Ffrench-Constant, C; Lyons, DA,期刊：Development, 页码：4443-4450 , 文章类型： Article，,卷期：2011年138-20] The majority of axons in the central nervous system (CNS) are eventually myelinated by oligodendrocytes, but whether the timing and extent of myelination in vivo reflect intrinsic properties of oligodendrocytes, or are r... Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis [作者：Stenzel, D; Lundkvist, A; Sauvaget, D; Busse, M; Graupera, M; van der Flier, A; Wijelath, ES; Murray, J; Sobel, M; Costell, M; Takahashi, S; Fassler, R; Yamaguchi, Y; Gutmann, DH; Hynes, RO; Gerhardt, H,期刊：Development, 页码：4451-4463 , 文章类型： Article，,卷期：2011年138-20] Fibronectin (FN) is a major component of the extracellular matrix and functions in cell adhesion, cell spreading and cell migration. In the retina, FN is transiently expressed and assembled on astrocytes (ACs), which gui... Islet1-mediated activation of the beta-catenin pathway is necessary for hindlimb initiation in mice [作者：Kawakami, Y; Marti, M; Kawakami, H; Itou, J; Quach, T; Johnson, A; Sahara, S; O'Leary, DDM; Nakagawa, Y; Lewandoski, M; Pfaff, S; Evans, SM; Belmonte, JCI,期刊：Development, 页码：4465-4473 , 文章类型： Article，,卷期：2011年138-20] The transcriptional basis of vertebrate limb initiation, which is a well-studied system for the initiation of organogenesis, remains elusive. Specifically, involvement of the beta-catenin pathway in limb initiation, as w... MIG-15 and ERM-1 promote growth cone directional migration in parallel to UNC-116 and WVE-1 [作者：Teuliere, J; Gally, C; Garriga, G; Labouesse, M; Georges-Labouesse, E,期刊：Development, 页码：4475-4485 , 文章类型： Article，,卷期：2011年138-20] Neurons require precise targeting of their axons to form a connected network and a functional nervous system. Although many guidance receptors have been identified, much less is known about how these receptors signal to ... Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development [作者：Wang, BP; Harrison, W; Overbeek, PA; Zheng, H,期刊：Development, 页码：4487-4497 , 文章类型： Article，,卷期：2011年138-20] Correct development of the cerebellum requires coordinated sonic hedgehog (Shh) signaling from Purkinje to granule cells. How Shh expression is regulated in Purkinje cells is poorly understood. Using a novel tyrosinase m...