- A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells
[作者：Marchetto, MCN; Carromeu, C; Acab, A; Yu, D; Yeo, GW; Mu, YL; Chen, G; Gage, FH; Muotri, AR,期刊：Cell, 页码：527-539 , 文章类型： Article，,卷期：2010年143-4]
- Autism spectrum disorders (ASD) are complex neurodevelopmental diseases in which different combinations of genetic mutations may contribute to the phenotype. Using Rett syndrome (RTT) as an ASD genetic model, we develope...
- RNA Polymerase II Subunits Link Transcription and mRNA Decay to Translation
[作者：Harel-Sharvit, L; Eldad, N; Haimovich, G; Barkai, O; Duek, L; Choder, M,期刊：Cell, 页码：552-563 , 文章类型： Article，,卷期：2010年143-4]
- Little is known about crosstalk between the eukaryotic transcription and translation machineries that operate in different cell compartments. The yeast proteins Rpb4p and Rpb7p represent one such link as they form a hete...
- A Family of Protein-Deglutamylating Enzymes Associated with Neurodegeneration
[作者：Rogowski, K; van Dijk, J; Magiera, MM; Bosc, C; Deloulme, JC; Bosson, A; Peris, L; Gold, ND; Lacroix, B; Grau, MB; Bec, N; Larroque, C; Desagher, S; Holzer, M; Andrieux, A; Moutin, MJ; Janke, C,期刊：Cell, 页码：564-578 , 文章类型： Article，,卷期：2010年143-4]
- Polyglutamylation is a posttranslational modification that generates glutamate side chains on tubulins and other proteins. Although this modification has been shown to be reversible, little is known about the enzymes cat...
- Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter
[作者：Victora, GD; Schwickert, TA; Fooksman, DR; Kamphorst, AO; Meyer-Hermann, M; Dustin, ML; Nussenzweig, MC,期刊：Cell, 页码：592-605 , 文章类型： Article，,卷期：2010年143-4]
- The germinal center (GC) reaction produces high-affinity antibodies by random mutation and selective clonal expansion of B cells with high-affinity receptors. The mechanism by which B cells are selected remains unclear, ...
- Epiblast Stem Cell Subpopulations Represent Mouse Embryos of Distinct Pregastrulation Stages
[作者：Han, DW; Tapia, N; Joo, JY; Greber, B; Arauzo-Bravo, MJ; Bernemann, C; Ko, K; Wu, GM; Stehling, M; Do, JT; Scholer, HR,期刊：Cell, 页码：617-627 , 文章类型： Article，,卷期：2010年143-4]
- Embryonic stem cells (ESCs) comprise at least two populations of cells with divergent states of pluripotency. Here, we show that epiblast stem cells (EpiSCs) also comprise two distinct cell populations that can be distin...
- A Genome-wide Drosophila Screen for Heat Nociception Identifies alpha 2 delta 3 as an Evolutionarily Conserved Pain Gene
[作者：Neely, GG; Hess, A; Costigan, M; Keene, AC; Goulas, S; Langeslag, M; Griffin, RS; Belfer, I; Dai, F; Smith, SB; Diatchenko, L; Gupta, V; Xia, CP; Amann, S; Kreitz, S; Heindl-Erdmann, C; Wolz, S; Ly, CV; Arora, S; Sarangi, R; Dan, D; Novatchkova, M; Rosenzweig, M; Gibson, DG; Truong, D; Schramek, D; Zoranovic, T; Cronin, SJF; Angjeli, B; Brune, K; Dietzl, G; Maixner, W; Meixner, A; Thomas, W; Pospisilik, JA; Alenius, M; Kress, M; Subramaniam, S; Garrity, PA; Bellen, HJ; Woolf, CJ; Penninger, JM,期刊：Cell, 页码：628-638 , 文章类型： Article，,卷期：2010年143-4]
- Worldwide, acute, and chronic pain affects 20% of the adult population and represents an enormous financial and emotional burden. Using genome-wide neuronal-specific RNAi knockdown in Drosophila, we report a global scree...
- Extensive In Vivo Metabolite-Protein Interactions Revealed by Large-Scale Systematic Analyses
[作者：Li, XY; Gianoulis, TA; Yip, KY; Gerstein, M; Snyder, M,期刊：Cell, 页码：639-650 , 文章类型： Article，,卷期：2010年143-4]
- Natural small compounds comprise most cellular molecules and bind proteins as substrates, products, cofactors, and ligands. However, a large-scale investigation of in vivo protein-small metabolite interactions has not be...
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