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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共7条记录   A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion [作者：Kahyo, T; Iwaizumi, M; Shinmura, K; Matsuura, S; Nakamura, T; Watanabe, Y; Yamada, H; Sugimura, H,期刊：Oncogene, 页码：4453-4463 , 文章类型： Article，,卷期：2011年30-44] Mitosis is the most conspicuous cell cycle phase, because it is the phase in which the dynamic physical distributions of cellular components into the two daughter cells occur. The separation of sister chromatids is espec... A novel interplay between oncogenic PFTK1 protein kinase and tumor suppressor TAGLN2 in the control of liver cancer cell motility [作者：Leung, WKC; Ching, AKK; Chan, AWH; Poon, TCW; Mian, H; Wong, AST; To, KF; Wong, N,期刊：Oncogene, 页码：4464-4475 , 文章类型： Article，,卷期：2011年30-44] The PFTK1 gene encodes a cdc2-related serine/threonine protein kinase that has been shown to confer cell migratory properties in hepatocellular carcinoma (HCC). However, the prognostic value and biological mechanism by w... p53 promotes cellular survival in a context-dependent manner by directly inducing the expression of haeme-oxygenase-1 [作者：Nam, SY; Sabapathy, K,期刊：Oncogene, 页码：4476-4486 , 文章类型： Article，,卷期：2011年30-44] A variety of cellular insults activate the tumour suppressor p53, leading generally to cell-cycle arrest or apoptosis. However, it is not inconceivable that cellular protective mechanisms may be required to keep cells al... Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt [作者：Hiraoka, D; Okumura, E; Kishimoto, T,期刊：Oncogene, 页码：4487-4497 , 文章类型： Article，,卷期：2011年30-44] Akt, also known as protein kinase B, has a central role in various signaling pathways that regulate cellular processes such as metabolism, proliferation and survival. On stimulation, phosphorylation of the activation loo... IRX1 influences peritoneal spreading and metastasis via inhibiting BDKRB2-dependent neovascularization on gastric cancer [作者：Jiang, J; Liu, W; Guo, X; Zhang, R; Zhi, Q; Ji, J; Zhang, J; Chen, X; Li, J; Zhang, J; Gu, Q; Liu, B; Zhu, Z; Yu, Y,期刊：Oncogene, 页码：4498-4508 , 文章类型： Article，,卷期：2011年30-44] The overexpression of IRX1 gene correlates with the growth arrest in gastric cancer. Furthermore, overexpression of IRX1 gene suppresses peritoneal spreading and long distance metastasis. To explore the precise mechanism... Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR [作者：Rosner, M; Hengstschlager, M,期刊：Oncogene, 页码：4509-4522 , 文章类型： Article，,卷期：2011年30-44] The tuberous sclerosis complex gene 2 (TSC2)/mammalian target of rapamycin (mTOR) pathway controls many cellular functions via phosphorylation of ribosomal protein S6 kinases (S6Ks). Alternative splicing and translation ... GLI1-dependent transcriptional repression of CYLD in basal cell carcinoma [作者：Kuphal, S; Shaw-Hallgren, G; Eberl, M; Karrer, S; Aberger, F; Bosserhoff, AK; Massoumi, R,期刊：Oncogene, 页码：4523-4530 , 文章类型： Article，,卷期：2011年30-44] CYLD is a deubiquitination enzyme that regulates different cellular processes, such as cell proliferation and cell survival. Mutation and loss of heterozygosity of the CYLD gene causes development of cylindromatosis, a b...