- Design, synthesis, and in vitro antiprotozoal, antimycobacterial activities of N-{2-[(7-chloroquinolin-4-yl)amino]ethyl}ureas
[作者:NAVAZUAZO CARLOS; ESTRADASOTO SAMUEL; GUERREROALVAREZ JORGE; LEONRIVERA ISMAEL; MARIA MOLINASALINAS GLORIA; SAIDFERNANDEZ SALVADOR; JESUS CHANBACAB MANUEL; CEDILLORIVERA ROBERTO; MOOPUC ROSA; MIRONLOPEZ GUMERSINDO; NAVARRETEVAZQUEZ GABRIEL,期刊:Bioorganic & Medicinal Chemistry, 页码:6398-6403 , 文章类型: Article,,卷期:2010年18-17]
- We have synthesized a new series of quinoline tripartite hybrids from chloroquine, ethambutol, and isoxyl drugs, using a short synthetic route. Compounds 1-8 were tested in vitro against five protozoa (Giardia intestinal...
- Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors
[作者:KANG IOUJIUN; WANG LIWEN; YEH TENGKUANG; LEE CHUNGCHI; LEE YENCHUN; HSU SHENGJU; WU YENSHIAN; WANG JINGCHYI; CHAO YUSHENG; YUEH ANDREW; CHERN JYHHAUR,期刊:Bioorganic & Medicinal Chemistry, 页码:6414-6421 , 文章类型: Article,,卷期:2010年18-17]
- A series of novel conformationally-restricted thiourea analogs were designed, synthesized, and evaluated for their anti-HCV activity. Herein we report the synthesis, structure-activity relationships (SARs), and pharmacok...
- New 4H-chromen-4-one and 2H-chromene derivatives as anti-picornavirus capsid-binders
[作者:CONTI CINZIA; DESIDERI NICOLETTA,期刊:Bioorganic & Medicinal Chemistry, 页码:6480-6488 , 文章类型: Article,,卷期:2010年18-17]
- Substituted (E)-3-styryl-4H-chromen-4-ones 1a-d, 3-[(1E,3E)-4-phenylbuta-1,3-dienyl]-4H-chromen-4-ones 2a-d, (E)-3-styryl-2H-chromenes 3a-d and 3-[(1E, 3E)-4-phenylbuta-1,3-dienyl]-2H-chromenes 4a-d were designed and syn...
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