- 1,6-Conjugate Addition of Nucleophiles to alpha,beta,gamma,delta-Diunsaturated Systems
[作者:SILVA EDUARDA M P; SILVA ARTUR M S,期刊:Synthesis, 页码:3109-3128 , 文章类型: Review,,卷期:2012年44-20]
- Herein, an overview of the most important developments and concepts related to the 1,6-conjugate addition reactions are reviewed. 1 Introduction 2 Transition-Metal-Catalyzed 1,6-Conjugate Additions 2.1 Copper-Mediated Re...
- Efficient Synthesis of 4-Amino-2-methoxy-7,8-dihydropyrido[4,3-d]pyrimidin-5-ones: Practical Access to a Novel Chemotype in the Development of DGAT-1 Inhibitors
[作者:BAHNCK KEVIN B; SHAVNYA ANDREI; TAO YONG; LILLEY SUSAN C; ANDREWS MELISSA P; ASPNES GARY E; BERNHARDSON DAVID J; BILL DAVID R; BUNDESMANN MARK W; DOW ROBERT L; KARKI KAPIL; LE TUNG; LI QIFANG; MUNCHHOF MICHAEL J; NEMATALLA ASAAD; NIHLAWI MOHAMMED; PATEL LEENA; PERREAULT CHRISTIAN; WALDO MICHAEL,期刊:Synthesis, 页码:3152-3157 , 文章类型: Article,,卷期:2012年44-20]
- A practical access to an unprecedented, fused bicyclic 4-amino-2-alkoxy-7,8-dihydropyrido[4,3-d]pyrimidin-5-one scaffold is developed. The synthesis of the potent inhibitor, 2-{4-[4-amino-2-methoxy-5-oxo-7,8-dihydropyrid...
- Synthesis of 2,4,6-Triazidopyridine and Its 3,5-Diiodo Derivative
[作者:CHAPYSHEV SERGEI V; CHERNYAK ALEXANDER V,期刊:Synthesis, 页码:3158-3160 , 文章类型: Article,,卷期:2012年44-20]
- 2,4,6-Trifluoropyridine was diiodinated with a mixture of potassium iodide and periodic acid in sulfuric acid at 55 degrees C to give 2,4,6-trifluoro-3,5-diiodopyridine in 85% yield. Both the starting trifluoropyridine a...
- Convenient Methods to Access Chiral Camphanyl Amine Derivatives by Sodium Borohydride Reduction of D-(-)-Camphorquinone Imines
[作者:PERIASAMY MARIAPPAN; SANJEEVAKUMAR NALLURI; REDDY POLIMERA OBULA,期刊:Synthesis, 页码:3185-3190 , 文章类型: Article,,卷期:2012年44-20]
- D-(-)-Camphorquinone imines prepared using methanolic ammonia, ethanol amine, exo-(-)-bornylamine, ethylene diamine, propylene diamine, and trans-(R, R)-1,2-diaminocyclohexane, upon reduction using sodium borohydride in ...
- Development of Tartaric Acid Derived Hydrogen-Bond Donors
[作者:LAUBER MARKUS BORIS; FROEHLICH ROLAND; PARADIES JAN,期刊:Synthesis, 页码:3209-3215 , 文章类型: Article,,卷期:2012年44-20]
- A flexible synthesis of bifunctional thiourea derivatives based on the TADDOL framework is described. Hydroxy as well as primary, secondary, and tertiary amino-substituted bifunctional hydrogen-bond donors were synthesiz...
- Palladium-Catalyzed Synthesis of Substituted Pyrido[2,3-d]pyridazines at Positions 5 and 8
[作者:IBRAHIM MOHAMED A; BLAISE EMILIE; LOZACH OLIVIER; SZALATA CLAUDE; SCHMITT MARTINE; ELETRAWY ABDALLAH S; ELAGAWANY MOHAMED; ELFEKY SAID A; ABDELSAMII ZAKRAIA K; MEIJER LAURENT; BOURGUIGNON JEANJACQUES; BIHEL FREDERIC,期刊:Synthesis, 页码:3216-3224 , 文章类型: Article,,卷期:2012年44-20]
- Several synthetic strategies were developed for the preparation of highly substituted pyrido[2,3-d]pyridazines. We particularly focused on the impact of the pyridine nitrogen atom on pyridazine ring reactivity toward aro...
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