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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共11条记录   Erythropoietin receptor contributes to melanoma cell survival in vivo [作者：Kumar, SM; Zhang, G; Bastian, BC; Arcasoy, MO; Karande, P; Pushparajan, A; Acs, G; Xu, X,期刊：Oncogene, 页码：1649-1660 , 文章类型： Article，,卷期：2012年31-13] Erythropoietin (Epo) is widely used clinically to treat anemia associated with various clinical conditions including cancer. Data from several clinical trials suggest significant adverse effect of Epo treatment on cancer... Efficacy of CHK inhibitors as single agents in MYC-driven lymphoma cells [作者：Ferrao, PT; Bukczynska, EP; Johnstone, RW; McArthur, GA,期刊：Oncogene, 页码：1661-1672 , 文章类型： Article，,卷期：2012年31-13] CHK1 and CHK2 function as effectors of cell cycle checkpoint arrest following DNA damage. Small molecule inhibitors of CHK proteins are under clinical evaluation in combination with chemotherapeutic agents known to induc... CAPC negatively regulates NF-kappa B activation and suppresses tumor growth and metastasis [作者：Liu, XF; Xiang, L; Zhang, Y; Becker, KG; Bera, TK; Pastan, I,期刊：Oncogene, 页码：1673-1682 , 文章类型： Article，,卷期：2012年31-13] CAPC, also known as LRRC26, is expressed in normal prostate and salivary gland. We developed a mAb to CAPC and used it to characterize the protein and study its function. CAPC protein was detected in normal prostate and ... Acceleration of clear cell renal cell carcinoma growth in mice following bevacizumab/Avastin treatment: the role of CXCL cytokines [作者：Grepin, R; Guyot, M; Jacquin, M; Durivault, J; Chamorey, E; Sudaka, A; Serdjebi, C; Lacarelle, B; Scoazec, JY; Negrier, S; Simonnet, H; Pages, G,期刊：Oncogene, 页码：1683-1694 , 文章类型： Article，,卷期：2012年31-13] The anti-VEGF targeted antibody bevacizumab (BVZ) has been approved for treating renal cell carcinomas (RCCs). Although BVZ increases the progression-free survival of patients with metastatic RCC, the effect on overall s... Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts [作者：Perna, D; Faga, G; Verrecchia, A; Gorski, MM; Barozzi, I; Narang, V; Khng, J; Lim, KC; Sung, WK; Sanges, R; Stupka, E; Oskarsson, T; Trumpp, A; Wei, CL; Muller, H; Amati, B,期刊：Oncogene, 页码：1695-1709 , 文章类型： Article，,卷期：2012年31-13] The transition from quiescence to proliferation is a key regulatory step that can be induced by serum stimulation in cultured fibroblasts. The transcription factor Myc is directly induced by serum mitogens and drives a s... Insulin-like growth factor-binding protein-1 (IGFBP-1) regulates human schwannoma proliferation, adhesion and survival [作者：Ammoun, S; Schmid, MC; Zhou, L; Ristic, N; Ercolano, E; Hilton, DA; Perks, CM; Hanemann, CO,期刊：Oncogene, 页码：1710-1722 , 文章类型： Article，,卷期：2012年31-13] Merlin is a tumour suppressor involved in the development of a variety of tumours including mesotheliomas. Neurofibromatosis type 2 (NF2), a dominantly inherited tumour disease, is also caused by loss of merlin. NF2 pati... Pancreatic beta-cells activate a JunB/ATF3-dependent survival pathway during inflammation [作者：Gurzov, EN; Barthson, J; Marhfour, I; Ortis, F; Naamane, N; Igoillo-Esteve, M; Gysemans, C; Mathieu, C; Kitajima, S; Marchetti, P; Orntoft, TF; Bakiri, L; Wagner, EF; Eizirik, DL,期刊：Oncogene, 页码：1723-1732 , 文章类型： Article，,卷期：2012年31-13] Destruction of insulin-producing pancreatic beta-cells by local autoimmune inflammation is a hallmark of type 1 diabetes. Histochemical analysis of pancreases from non-obese diabetic mice indicated activation of the tran... Targeting activation-induced cytidine deaminase prevents colon cancer development despite persistent colonic inflammation [作者：Takai, A; Marusawa, H; Minaki, Y; Watanabe, T; Nakase, H; Kinoshita, K; Tsujimoto, G; Chiba, T,期刊：Oncogene, 页码：1733-1742 , 文章类型： Article，,卷期：2012年31-13] Inflammatory bowel disease (IBD) is an important etiologic factor in the development of colorectal cancer. However, the mechanism underlying carcinogenesis through chronic inflammation is still unknown. Activation-induce... DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer [作者：Lopez-Serra, P; Esteller, M,期刊：Oncogene, 页码：1609-1622 , 文章类型： Review，,卷期：2012年31-13] MicroRNAs (miRNAs) are recognized as being central players in many biological processes and cellular pathways. Their roles in disease have been highlighted first by observation of their aberrant expression profiles in hu... MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression [作者：Oneyama, C; Morii, E; Okuzaki, D; Takahashi, Y; Ikeda, J; Wakabayashi, N; Akamatsu, H; Tsujimoto, M; Nishida, T; Aozasa, K; Okada, M,期刊：Oncogene, 页码：1623-1635 , 文章类型： Article，,卷期：2012年31-13] The tyrosine kinase c-Src is upregulated in various human cancers; however, the molecular mechanisms underlying c-Src-mediated tumor progression remain unclear. Here we show that downregulation of microRNA (miR)-542-3p i... A role for caveolin-1 in desmoglein binding and desmosome dynamics [作者：Brennan, D; Peltonen, S; Dowling, A; Medhat, W; Green, KJ; Wahl, JK; Del Galdo, F; Mahoney, MG,期刊：Oncogene, 页码：1636-1648 , 文章类型： Article，,卷期：2012年31-13] Desmoglein-2 (Dsg2) is a desmosomal cadherin that is aberrantly expressed in human skin carcinomas. In addition to its well-known role in mediating intercellular desmosomal adhesion, Dsg2 regulates mitogenic signaling th...