- Integrating developmental signals: a Hippo in the (path) way
[作者：Mauviel, A; Nallet-Staub, F; Varelas, X,期刊：Oncogene, 页码：1743-1756 , 文章类型： Review，,卷期：2012年31-14]
- The Hippo pathway, a signaling cascade that controls cell cycle progression, apoptosis and cell differentiation, has emerged as a fundamental regulator of many physiological and pathological processes. Recent studies hav...
- HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs
[作者：Zhang, H; Wong, CCL; Wei, H; Gilkes, DM; Korangath, P; Chaturvedi, P; Schito, L; Chen, J; Krishnamachary, B; Winnard, PT; Raman, V; Zhen, L; Mitzner, WA; Sukumar, S; Semenza, GL,期刊：Oncogene, 页码：1757-1770 , 文章类型： Article，,卷期：2012年31-14]
- Most cases of breast cancer (BrCa) mortality are due to vascular metastasis. BrCa cells must intravasate through endothelial cells (ECs) to enter a blood vessel in the primary tumor and then adhere to ECs and extravasate...
- Promotion of cytoplasmic mislocalization of p27 by Helicobacter pylori in gastric cancer
[作者：Wen, S; So, Y; Singh, K; Slingerland, JM; Resnick, MB; Zhang, S; Ruiz, V; Moss, SF,期刊：Oncogene, 页码：1771-1780 , 文章类型： Article，,卷期：2012年31-14]
- The cyclin-dependent kinase (CDK) inhibitor p27 has an important role in cell cycle regulation. Reduced expression of p27 is commonly associated with poor prognosis in many malignancies, including gastric cancer. Cytopla...
- Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells
[作者：Dawson, JC; Timpson, P; Kalna, G; Machesky, LM,期刊：Oncogene, 页码：1781-1793 , 文章类型： Article，,卷期：2012年31-14]
- Mtss1 is located within chromosomal region 8q23-24, which is one of the three most commonly amplified regions in head and neck squamous cell carcinoma (HNSCC). Mtss1 is lost in metastatic cells, but confusingly is common...
- Pim1 kinase is required to maintain tumorigenicity in MYC-expressing prostate cancer cells
[作者：Wang, J; Anderson, PD; Luo, W; Gius, D; Roh, M; Abdulkadir, SA,期刊：Oncogene, 页码：1794-1803 , 文章类型： Article，,卷期：2012年31-14]
- PIM1 kinase and MYC are commonly co-expressed in human prostate cancer and synergize to induce rapidly progressing prostate cancer in mouse models. Deficiency of the Pim kinase genes is well tolerated in vivo, suggesting...
- c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression
[作者：Ganguly, SS; Fiore, LS; Sims, JT; Friend, JW; Srinivasan, D; Thacker, MA; Cibull, ML; Wang, C; Novak, M; Kaetzel, DM; Plattner, R,期刊：Oncogene, 页码：1804-1816 , 文章类型： Article，,卷期：2012年31-14]
- Despite 35 years of clinical trials, there is little improvement in 1-year survival rates for patients with metastatic melanoma, and the disease is essentially untreatable if not cured surgically. The paucity of chemothe...
- A 19S proteasomal subunit cooperates with an ERK MAPK-regulated degron to regulate accumulation of Fra-1 in tumour cells
[作者：Pakay, JL; Diesch, J; Gilan, O; Yip, YY; Sayan, E; Kolch, W; Mariadason, JM; Hannan, RD; Tulchinsky, E; Dhillon, AS,期刊：Oncogene, 页码：1817-1824 , 文章类型： Article，,卷期：2012年31-14]
- Fos-related antigen-1 (Fra-1) is a member of the Activator Protein-1 (AP-1) transcription factor superfamily that is overexpressed in a variety of cancers, including colon, breast, lung, bladder and brain. High Fra-1 lev...
- Rack1 protects N-terminal phosphorylated c-Jun from Fbw7-mediated degradation
[作者：Zhang, J; Zhu, F; Li, X; Dong, Z; Xu, Y; Peng, C; Li, S; Cho, YY; Yao, K; Zykova, TA; Bode, AM; Dong, Z,期刊：Oncogene, 页码：1835-1844 , 文章类型： Article，,卷期：2012年31-14]
- The c-Jun transcription factor is a highly unstable oncoprotein. Several ubiquitin ligases mediate c-Jun degradation. However, c-Jun can be stabilized once it is phosphorylated at the N-terminus by c-Jun N-terminal kinas...
- FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer
[作者：Karadedou, CT; Gomes, AR; Chen, J; Petkovic, M; Ho, KK; Zwolinska, AK; Feltes, A; Wong, SY; Chan, KYK; Cheung, YN; Tsang, JWH; Brosens, JJ; Khoo, US; Lam, EWF,期刊：Oncogene, 页码：1845-1858 , 文章类型： Article，,卷期：2012年31-14]
- Vascular endothelial growth factor (VEGF) has a central role in breast cancer development and progression, but the mechanisms that control its expression are poorly understood. Breast cancer tissue microarrays revealed a...
- Loss of LIN9, a member of the DREAM complex, cooperates with SV40 large T antigen to induce genomic instability and anchorage-independent growth
[作者：Hauser, S; Ulrich, T; Wurster, S; Schmitt, K; Reichert, N; Gaubatz, S,期刊：Oncogene, 页码：1859-1868 , 文章类型： Article，,卷期：2012年31-14]
- The DREAM complex is an important regulator of mitotic gene expression during the cell cycle. Here we report that inactivation of LIN9, a subunit of DREAM, results in premature senescence, which can be overcome by the SV...
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