- Four proteins governing overangiogenic endothelial cell phenotype in patients with multiple myeloma are plausible therapeutic targets
[作者：Berardi, S; Caivano, A; Ria, R; Nico, B; Savino, R; Terracciano, R; De Tullio, G; Ferrucci, A; De Luisi, A; Moschetta, M; Mangialardi, G; Catacchio, I; Basile, A; Guarini, A; Zito, A; Ditonno, P; Musto, P; Dammacco, F; Ribatti, D; Vacca, A,期刊：Oncogene, 页码：2258-2269 , 文章类型： Article，,卷期：2012年31-18]
- Bone marrow (BM) angiogenesis has an important role in the initiation and progression of multiple myeloma (MM). We looked at novel mechanisms of vessel formation in patients with MM through a comparative proteomic analys...
- Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas
[作者：Basu-Roy, U; Seo, E; Ramanathapuram, L; Rapp, TB; Perry, JA; Orkin, SH; Mansukhani, A; Basilico, C,期刊：Oncogene, 页码：2270-2282 , 文章类型： Article，,卷期：2012年31-18]
- Tumors are thought to be sustained by a reservoir of self-renewing cells, termed tumor-initiating cells or cancer stem cells. Osteosarcomas are high-grade sarcomas derived from osteoblast progenitor cells and are the mos...
- Non-canonical HIF-2 alpha function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop
[作者：Stiehl, DP; Bordoli, MR; Abreu-Rodriguez, I; Wollenick, K; Schraml, P; Gradin, K; Poellinger, L; Kristiansen, G; Wenger, RH,期刊：Oncogene, 页码：2283-2297 , 文章类型： Article，,卷期：2012年31-18]
- Tumor progression is intrinsically tied to the clonal selection of tumor cells with acquired phenotypes allowing to cope with a hostile microenvironment. Hypoxia-inducible factors (HIFs) master the transcriptional respon...
- MTSS1, a novel target of DNA methyltransferase 3B, functions as a tumor suppressor in hepatocellular carcinoma
[作者：Fan, H; Chen, L; Zhang, F; Quan, Y; Su, X; Qiu, X; Zhao, Z; Kong, KL; Dong, S; Song, Y; Chan, THM; Guan, XY,期刊：Oncogene, 页码：2298-2308 , 文章类型： Article，,卷期：2012年31-18]
- DNA methyltransferase 3B (DNMT3B) mediates gene silencing via epigenetic mechanisms during hepatocellular carcinoma (HCC) progression. We aimed to identify novel targets of DNMT3B and their potential regulatory mechanism...
- Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells
[作者：Yue, P; Zhang, X; Paladino, D; Sengupta, B; Ahmad, S; Holloway, RW; Ingersoll, SB; Turkson, J,期刊：Oncogene, 页码：2309-2322 , 文章类型： Article，,卷期：2012年31-18]
- We present evidence that the cisplatin-resistant human ovarian cancer lines, A2780S/CP1 (S/CP1), A2780S/CP3 (S/CP3) and A2780S/CP5 (S/CP5), derived by subjecting the sensitive A2780S ovarian cancer line to multiple round...
- Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2
[作者：Garcia, CB; Shaffer, CM; Alfaro, MP; Smith, AL; Sun, J; Zhao, Z; Young, PP; VanSaun, MN; Eid, JE,期刊：Oncogene, 页码：2323-2334 , 文章类型： Article，,卷期：2012年31-18]
- Cell identity is determined by its gene expression programs. The ability of a cell to change its identity and produce cell types outside its lineage is achieved by the activity of transcription controllers capable of rep...
- The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription
[作者：Hsu, CH; Peng, KL; Jhang, HC; Lin, CH; Wu, SY; Chiang, CM; Lee, SC; Yu, WCY; Juan, LJ,期刊：Oncogene, 页码：2335-2349 , 文章类型： Article，,卷期：2012年31-18]
- Expression of viral proteins causes important epigenetic changes leading to abnormal cell growth. Whether viral proteins directly target histone methyltransferases (HMTs), a key family enzyme for epigenetic regulation, a...
- Differential roles for the p101 and p84 regulatory subunits of PI3K gamma in tumor growth and metastasis
[作者：Brazzatti, JA; Klingler-Hoffmann, M; Haylock-Jacobs, S; Harata-Lee, Y; Niu, M; Higgins, MD; Kochetkova, M; Hoffmann, P; McColl, SR,期刊：Oncogene, 页码：2350-2361 , 文章类型： Article，,卷期：2012年31-18]
- Phosphoinositide 3-kinase gamma (PI3K gamma) consists of a catalytic subunit p110 gamma, which forms mutually exclusive dimers with one of the regulatory subunits called p101 and p84/p87(PIKAP). Recently, PI3K gamma emer...
- A role for collagen XXIII in cancer cell adhesion, anchorage-independence and metastasis
[作者：Spivey, KA; Chung, I; Banyard, J; Adini, I; Feldman, HA; Zetter, BR,期刊：Oncogene, 页码：2362-2372 , 文章类型： Article，,卷期：2012年31-18]
- Collagen XXIII is a transmembrane collagen previously shown to be upregulated in metastatic prostate cancer that has been used as a tissue and fluid biomarker for non-small cell lung cancer and prostate cancer. To determ...
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