- Separating genetic and hemodynamic defects in neuropilin 1 knockout embryos
[作者:Jones, EAV; Yuan, L; Breant, C; Watts, RJ; Eichmann, A,期刊:Development, 页码:2479-2488 , 文章类型: Article,,卷期:2008年135-14]
- Targeted inactivation of genes involved in murine cardiovascular development frequently leads to abnormalities in blood flow. As blood fluid dynamics play a crucial role in shaping vessel morphology, the presence of flow...
- dmd-3, a doublesex-related gene regulated by tra-1, governs sex-specific morphogenesis in C. elegans
[作者:Mason, DA; Rabinowitz, JS; Portman, DS,期刊:Development, 页码:2373-2382 , 文章类型: Article,,卷期:2008年135-14]
- Although sexual dimorphism is ubiquitous in animals, the means by which sex determination mechanisms trigger specific modifications to shared structures is not well understood. In C. elegans, tail tip morphology is highl...
- Patterns of cell signaling pathway activation that characterize mammary development
[作者:Andrechek, ER; Mori, S; Rempel, RE; Chang, JT; Nevins, JR,期刊:Development, 页码:2403-2413 , 文章类型: Article,,卷期:2008年135-14]
- Previous work has detailed the histological and biochemical changes associated with mammary development and remodeling. We have now made use of gene expression profiling, and in particular of the previously described sig...
- Placental rescue reveals a sole requirement for c-Myc in embryonic erythroblast survival and hematopoietic stem cell function
[作者:Dubois, NC; Adolphe, C; Ehninger, A; Wang, RA; Robertson, EJ; Trumpp, A,期刊:Development, 页码:2455-2465 , 文章类型: Article,,卷期:2008年135-14]
- The c-Myc protein has been implicated in playing a pivotal role in regulating the expression of a large number of genes involved in many aspects of cellular function. Consistent with this view, embryos lacking the c-myc ...
- c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo
[作者:He, C; Hu, HQ; Braren, R; Fong, SY; Trumpp, A; Carlson, TR; Wang, RA,期刊:Development, 页码:2467-2477 , 文章类型: Article,,卷期:2008年135-14]
- The c-myc proto-oncogene, which is crucial for the progression of many human cancers, has been implicated in key cellular processes in diverse cell types, including endothelial cells that line the blood vessels and are c...
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