- The Ecdysone-inducible zinc-finger transcription factor Crol regulates Wg transcription and cell cycle progression in Drosophila
[作者:Mitchell, N; Cranna, N; Richardson, H; Quinn, L,期刊:Development, 页码:2707-2716 , 文章类型: Article,,卷期:2008年135-16]
- The steroid hormone Ecdysone is crucial for developmental cell death, proliferation and morphogenesis in Drosophila. Herein, we delineate a molecular pathway linking Ecdysone signalling to cell cycle regulation in the Dr...
- Hedgehog signaling is involved in development of the neocortex
[作者:Komada, M; Saitsu, H; Kinboshi, M; Miura, T; Shiota, K; Ishibashi, M,期刊:Development, 页码:2717-2727 , 文章类型: Article,,卷期:2008年135-16]
- Sonic hedgehog (Shh) function is essential for patterning and cell fate specification, particularly in ventral regions of the central nervous system. It is also a crucial mitogen for cerebellar granule neuron precursors ...
- Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development
[作者:Wan, LB; Pan, H; Hannenhalli, S; Cheng, Y; Ma, J; Fedoriw, A; Lobanenkov, V; Latham, KE; Schultz, RM; Bartolomei, MS,期刊:Development, 页码:2729-2738 , 文章类型: Article,,卷期:2008年135-16]
- CTCF is a multifunctional nuclear factor involved in epigenetic regulation. Despite recent advances that include the systematic discovery of CTCF-binding sites throughout the mammalian genome, the in vivo roles of CTCF i...
- The C-elegans F-spondin family protein SPON-1 maintains cell adhesion in neural and non-neural tissues
[作者:Woo, WM; Berry, EC; Hudson, ML; Swale, RE; Goncharov, A; Chisholm, AD,期刊:Development, 页码:2747-2756 , 文章类型: Article,,卷期:2008年135-16]
- The F-spondin family of extracellular matrix proteins has been implicated in axon outgrowth, fasciculation and neuronal cell migration, as well as in the differentiation and proliferation of non-neuronal cells. In screen...
- Conditional ablation of Notch signaling in pancreatic development
[作者:Nakhai, H; Siveke, JT; Klein, B; Mendoza-Torres, L; Mazur, PK; Algul, H; Radtke, F; Strobl, L; Zimber-Strobl, U; Schmid, RM,期刊:Development, 页码:2757-2765 , 文章类型: Article,,卷期:2008年135-16]
- The role of the Notch signaling members Notch1, Notch2 and Rbpj in exocrine pancreatic development is not well defined. We therefore analyzed conditional pancreas-specific Rbpj and combined Notch1/Notch2 knockout mice us...
- Crucial role of vHNF1 in vertebrate hepatic specification
[作者:Lokmane, L; Haumaitre, C; Garcia-Villalba, P; Anselme, I; Schneider-Maunoury, S; Cereghini, S,期刊:Development, 页码:2777-2786 , 文章类型: Article,,卷期:2008年135-16]
- Mouse liver induction occurs via the acquisition of ventral endoderm competence to respond to inductive signals from adjacent mesoderm, followed by hepatic specification. Little is known about the regulatory circuit invo...
- Cell-type-specific transcription of prospero is controlled by combinatorial signaling in the Drosophila eye
[作者:Hayashi, T; Xu, CY; Carthew, RW,期刊:Development, 页码:2787-2796 , 文章类型: Article,,卷期:2008年135-16]
- In Drosophila, Notch and Egfr signaling regulate the determination of many cell types, and yet how these common signals generate cell-specific transcription is not well understood. In the compound eye, prospero ( pros) i...
- BMP2 and BMP7 play antagonistic roles in feather induction
[作者:Michon, F; Forest, L; Collomb, E; Demongeot, J; Dhouailly, D,期刊:Development, 页码:2797-2805 , 文章类型: Article,,卷期:2008年135-16]
- Feathers, like hairs, first appear as primordia consisting of an epidermal placode associated with a dermal condensation that is necessary for the continuation of their differentiation. Previously, the BMPs have been pro...
- Origin and shaping of the laterality organ in zebrafish
[作者:Oteiza, P; Koeppen, M; Concha, ML; Heisenberg, CP,期刊:Development, 页码:2807-2813 , 文章类型: Article,,卷期:2008年135-16]
- Handedness of the vertebrate body plan critically depends on transient embryonic structures/ organs that generate cilia-dependent leftward fluid flow within constrained extracellular environments. Although the function o...
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