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  • The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
    [作者:Alvarez, JI; Dodelet-Devillers, A; Kebir, H; Ifergan, I; Fabre, PJ; Terouz, S; Sabbagh, M; Wosik, K; Bourbonniere, L; Bernard, M; van Horssen, J; de Vries, HE; Charron, F; Prat, A,期刊:Science, 页码:1727-1731 , 文章类型: Article,,卷期:2011年334-6063]
  • The blood-brain barrier (BBB) is composed of tightly bound endothelial cells (ECs) and perivascular astrocytes that regulate central nervous system (CNS) homeostasis. We showed that astrocytes secrete Sonic hedgehog and ...
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