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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共8条记录   Dengue vaccines: state of the art [作者：Swaminathan, S; Batra, G; Khanna, N,期刊：Expert Opinion on Therapeutic Patents, 页码：819-835 , 文章类型： Review，,卷期：2010年20-6] Importance of the field: Dengue is a significant public health problem transcending geographical boundaries to place nearly 50% of the global population at risk. A vaccine to prevent dengue is an unmet need that should b... Novel substituted heteroaromatic compounds as inhibitors of stearoyl-CoA desaturase [作者：Dobrzyn, P; Dobrzyn, A,期刊：Expert Opinion on Therapeutic Patents, 页码：849-853 , 文章类型： Article，,卷期：2010年20-6] Stearoyl-CoA desaturase 1 (SCD1) has been implicated as a novel therapeutic target for the treatment of a variety of metabolic diseases, including diabetes, obesity, hepatic steatosis, atherosclerosis and cardiovascular ... Epstein-Barr virus: novel patented therapeutics [作者：De Paoli, P,期刊：Expert Opinion on Therapeutic Patents, 页码：807-818 , 文章类型： Review，,卷期：2010年20-6] Importance of the field: Therapeutic strategies against Epstein-Barr virus (EBV) infection and associated cancers are still limited. Due to the primary role of this virus in the pathogenesis of these diseases, molecules ... 5-HT7 receptor modulators: a medicinal chemistry survey of recent patent literature (2004-2009) [作者：Leopoldo, M; Lacivita, E; Berardi, F; Perrone, R,期刊：Expert Opinion on Therapeutic Patents, 页码：739-754 , 文章类型： Review，,卷期：2010年20-6] Importance of the field: The 5-HT7 receptors are discretely localized within the CNS (thalamus, hypothalamus, limbic and cortical regions). The 5-HT7 receptors are also present in smooth muscle cells from blood vessels a... Sodium channel blockers for neuropathic pain [作者：Zuliani, V; Rivara, M; Fantini, M; Costantino, G,期刊：Expert Opinion on Therapeutic Patents, 页码：755-779 , 文章类型： Review，,卷期：2010年20-6] Importance of the field: The voltage-gated sodium channels (VGSCs) play a fundamental role in controlling cellular excitability and their abnormal activity is related to several pathological processes, including cardiac ... Analysis of patents on anti-allergic therapies issued in China from 1988 to 2008 [作者：Zhang, S; Zeng, XN; Wei, JF; Li, S; He, SH,期刊：Expert Opinion on Therapeutic Patents, 页码：727-737 , 文章类型： Article，,卷期：2010年20-6] Background: The prevalence of allergic diseases has increased dramatically in recent decades. Therefore, there is a pressing need for the development of effective anti-allergic services worldwide. However, little is know... Selectin inhibitors: a patent review [作者：Bedard, PW; Kaila, N,期刊：Expert Opinion on Therapeutic Patents, 页码：781-793 , 文章类型： Review，,卷期：2010年20-6] Importance of the field: Selectins play a significant and well-documented role in inflammation and immune response. They initiate tethering and rolling of blood borne leukocytes leading to their activation, adhesion and ... Carbonic anhydrase inhibition as a cancer therapy: a review of patent literature, 2007-2009 [作者：Poulsen, SA,期刊：Expert Opinion on Therapeutic Patents, 页码：795-806 , 文章类型： Review，,卷期：2010年20-6] Importance of the field: The functional contribution of membrane-bound extracellular carbonic anhydrases (CAs) to hypoxic tumor growth and progression has long been hypothesized; however, recent convergent evidence from ...