- Characterization of Self-Association and Heteroassociation of Bacterial Cell Division Proteins FtsZ and ZipA in Solution by Composition Gradient-Static Light Scattering
[作者:Martos, A; Alfonso, C; Lopez-Navajas, P; Ahijado-Guzman, R; Mingorance, J; Minton, AP; Rivas, G,期刊:Biochemistry, 页码:10780-10787 , 文章类型: Article,,卷期:2010年49-51]
- We have characterized the self-association of FtsZ in its GDP-bound state (GDP-FtsZ) and the heteroassociation of FtsZ and a soluble recombinant ZipA (sZipA) lacking the N-terminal transmembrane domain by means of compos...
- Identification and Characterization of a Luciferase Isotype in the Japanese Firefly, Luciola cruciata, Involving in the Dim Glow of Firefly Eggs
[作者:Oba, Y; Mori, N; Yoshida, M; Inouye, S,期刊:Biochemistry, 页码:10788-10795 , 文章类型: Article,,卷期:2010年49-51]
- We isolated the cDNA of a luciferase isotype (LcLuc2) from the Japanese firefly, Luciola cruciata (Lampyridae, Coleoptera). The gene product of LcLuc2 (LcLuc2) showed 59% amino acid identity with firefly luciferase LcLuc...
- Stability and Membrane Orientation of the Fukutin Transmembrane Domain: A Combined Multiscale Molecular Dynamics and Circular Dichroism Study
[作者:Holdbrook, DA; Leung, YM; Piggot, TJ; Marius, P; Williamson, PTF; Khalid, S,期刊:Biochemistry, 页码:10796-10802 , 文章类型: Article,,卷期:2010年49-51]
- The N-terminal domain of fukutin-I has been implicated in the localization of the protein in the endoplasmic reticulum and Golgi Apparatus. It has been proposed to mediate this through its interaction with the thinner li...
- Role of Zinc in Isoform-Selective Inhibitor Binding to Neuronal Nitric Oxide Synthase
[作者:Delker, SL; Xue, FT; Li, HY; Jamal, J; Silverman, RB; Poulos, TL,期刊:Biochemistry, 页码:10803-10810 , 文章类型: Article,,卷期:2010年49-51]
- In previous studies [Delker, S. L., et al. (2010), J. Am. Chem. Soc. 132, 5437-5442], we determined the crystal structures of neuronal nitric oxide synthase (nNOS) in complex with nNOS-selective chiral pyrrolidine inhibi...
- Conformational Dynamics of the Anthrax Lethal Factor Catalytic Center
[作者:Dalkas, GA; Chasapis, CT; Gkazonis, PV; Bentrop, D; Spyroulias, GA,期刊:Biochemistry, 页码:10767-10769 , 文章类型: Article,,卷期:2010年49-51]
- Anthrax lethal factor (LF) is a zinc-metalloprotease that together with the protective antigen constitutes anthrax lethal toxin, which is the most prominent virulence factor of the anthrax disease. The solution nuclear m...
- A Rewired Green Fluorescent Protein: Folding and Function in a Nonsequential, Noncircular GFP Permutant
[作者:Reeder, PJ; Huang, YM; Dordick, JS; Bystroff, C,期刊:Biochemistry, 页码:10773-10779 , 文章类型: Article,,卷期:2010年49-51]
- The sequential order of secondary structural elements in proteins affects the folding and activity to an unknown extent. To test the dependence on sequential connectivity, we reconnected secondary structural elements by ...
- NMR Studies of the Stability, Protonation States, and Tautomerism of C-13- and N-15-Labeled Aldimines of the Coenzyme Pyridoxal 5 '-Phosphate in Water
[作者:Chan-Huot, M; Sharif, S; Tolstoy, PM; Toney, MD; Limbach, HH,期刊:Biochemistry, 页码:10818-10830 , 文章类型: Article,,卷期:2010年49-51]
- We have measured the pH-dependent H-1, C-13, and N-15 NMR spectra of pyridoxal 5'-phosphate (C-13(2)-PLP) mixed with equal amounts of either doubly N-15-labeled diaminopropane, N-15(alpha)-labeled. L-lysine, or N-15(epsi...
- Ligand-Induced Formation of a Transient Tryptophan Synthase Complex with alpha beta beta Subunit Stoichiometry
[作者:Ehrmann, A; Richter, K; Busch, F; Reimann, J; Albers, SV; Sterner, R,期刊:Biochemistry, 页码:10842-10853 , 文章类型: Article,,卷期:2010年49-51]
- The prototypical tryptophan synthases form a stable heterotetrameric alpha beta beta alpha complex in which the constituting TrpA and TrpB1 subunits activate each other in a bidirectional manner. The hyperthermophilic ar...
- Bombyx Adipokinetic Hormone Receptor Activates Extracellular Signal-Regulated Kinase 1 and 2 via G Protein-Dependent PKA and PKC but beta-Arrestin-Independent Pathways
[作者:Huang, HS; He, XB; Deng, XY; Li, G; Ying, GY; Sun, Y; Shi, LG; Benovic, JL; Zhou, NM,期刊:Biochemistry, 页码:10862-10872 , 文章类型: Article,,卷期:2010年49-51]
- Neuropeptides of the adipokinetic hormone (AKH) family are among the best studied hormone peptides. They play important roles in insect hemolymph sugar homeostasis, larval lipolysis, and storage-fat mobilization. Mechani...
- Molecular Basis for the Differences in Lipid and Lipoprotein Binding Properties of Human Apolipoproteins E3 and E4
[作者:Nguyen, D; Dhanasekaran, P; Nickel, M; Nakatani, R; Saito, H; Phillips, MC; Lund-Katz, S,期刊:Biochemistry, 页码:10881-10889 , 文章类型: Article,,卷期:2010年49-51]
- Human apolipoprotein (apo) E4 binds preferentially to very low-density lipoproteins (VLDLs), whereas apoE3 binds preferentially to high-density lipoproteins (HDLs), resulting in different plasma cholesterol levels for th...
- Allosteric Regulation of Glycogen Synthase Kinase 3 beta: A Theoretical Study
[作者:Buch, I; Fishelovitch, D; London, N; Raveh, B; Wolfson, HJ; Nussinov, R,期刊:Biochemistry, 页码:10890-10901 , 文章类型: Article,,卷期:2010年49-51]
- Glycogen synthase kinase 3 beta (GSK-3 beta) is a serine-threonine kinase belonging to the CMGC family that plays a key role in many biological processes, such as glucose metabolism, cell cycle regulation, and proliferat...
|